TWiV 938: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin reviews the public health response to poliovirus in New York, impact of mandatory influenza vaccination, monkeypox in a young infant, health care worker exposure to monkeypox virus, monkeypox testing delays, transmission potential of monkeypox virus, TPOXX trial for monkeypox, detection of SARS-CoV-2 subgenomic mRNA, mucosal IgA against SARS-CoV-2, BNT262b2 against Omicron, awareness and use of SARS-CoV-2 antivirals, comparable outcomes for Bebtelovimab and Nirmatrelvir, and COVID-19 and Alzheimer's disease. (Source: virology blog)
Source: virology blog - September 24, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs
Face Mask Detects Respiratory Viruses, Alerts User
Scientists at Shanghai Tongji University in China have created a face mask that can alert the wearer to the presence of respiratory viruses in the surrounding environment, including the viruses behind COVID-19 and influenza. The mask includes aptamers, which are short sequences of DNA or RNA that can bind to protein targets. When viral particles bind to the aptamers, ion-gated transistors boost the signal so that the mask can sensitively detect small amounts of virus. The mask sends a message to the wearer’s smartphone within 10 minutes of detecting the virus. The technology could be very valuable for healthcare staff or...
Source: Medgadget - September 22, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Public Health Source Type: blogs
TWiV 936: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses detection of a highly divergent type 3 vaccine-derived poliovirus in a child with a severe primary immunodeficiency disorder, severe respiratory illnesses associated with rhinoviruses and/or enteroviruses including EV-D68, effects of vaccination and previous infection on Omicron infections in children, COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years or older in 13 US states, effectiveness of COVID-19 vaccines over time prior to Omicron emergence in Ontario, Canada, nasal IgA wanes 9 months after hospitalization with COVID-19 an...
Source: virology blog - September 17, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
September 08, 2022 Edition-----In the US we are seeing the outcomes of Climate Change really of and running with droughts and fires etc. Biden amped up the partisan divide with a fiery anti-Republican speech!In Russia the last leader of Soviet Russia died.In the UK we have a new PM while in Europe the energy crisis is just getting worse.In OZ we have survived the Jobs and Skills Summit with 36 prearranged outcomes. Stage management +++ in action. The GP crisis is not being addressed fully and worries regarding the Global Economy - esp. China - worsen.-----Major Issues.-----https://www.afr.com/work-and-careers/educati...
Source: Australian Health Information Technology - September 8, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Commentators and Journalists Weigh In On Digital Health And Related Privacy, Safety, Social Media And Security Matters. Lots Of Interesting Perspectives - August 23, 2022.
-----This weekly blog is to explore the news around the larger issues around Digital Health, data security, data privacy, AI / ML. technology, social media and related matters.I will also try to highlightADHA Propagandawhen I come upon it.Just so we keep count, the latest Notes from the ADHA Board were dated 6 December, 2018 and we have seen none since! It ’s pretty sad!Note: Appearance here is not to suggest I see any credibility or value in what follows. I will leave it to the reader to decide what is worthwhile and what is not! The point is to let people know what is being said / published that I have come upon.-----h...
Source: Australian Health Information Technology - August 23, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
The Nihilistic AAP Bronchiolitis Guidelines
Not only has the COVID-19 pandemic killed millions of people, but it has also caused disruptions in every imaginable aspect of our lives. One has been the seasonality of other diseases like influenza and respiratory syncytial virus infection. RSV infection is typically a winter disease, but here we are in the summer months and our pediatric emergency department is flooded with infants infected with RSV.I expressed concern about the 2014 American Academy of Pediatrics bronchiolitis guidelines three years ago. (EMN. 2019;41[1]:31; http://bit.ly/2TlwNj9.) Those comments have proven to have real-life clinical releva...
Source: M2E Too! Mellick's Multimedia EduBlog - August 5, 2022 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Weekly Australian Health IT Links – 1 August, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----Quite a lot this week – especially regarding the NBN and Labor trying to regain control of what it is actually for – service provision – and not making a huge profit – in their view. Love the new Minister has ambitions to be maximally photogenic and not a ‘techie’!Otherwise all sorts of fun things!-----https://www.ausd...
Source: Australian Health Information Technology - August 1, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Flu Is Making Comeback. Here ’s What We Can Do About It
Jeffrey A. SingerAfter being nearly absent in 2020 and 2021, influenza cases are making a comeback. In fact, cases are up ‐tickingunusually late in the year. The Centers for Disease Control and Prevention (CDC)reported on April 15 that the majority of cases are H3N2, “antigenically different from the vaccine reference viruses.” This explains why the latest flu vaccine is only16 percent effective in reducing the chances of a moderate to severe infection. As of April 15, the CDC reported at least 4.3 million flu illnesses, 42,000 hospitalizations, and 2,500 deaths from the flu.Public health experts attribu...
Source: Cato-at-liberty - April 18, 2022 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs
TWiV 887: Bonfire of the monocytes
TWiV explains why this season's influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19. (Source: virology blog)
Source: virology blog - April 10, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antibody dependent enhancement coronavirus COVID-19 Fc receptor fucosylation glycosylation H3N2 inflammation influenza vaccine pandemic SARS-CoV-22 viral viruses Source Type: blogs
Lymphoid Follicle Chip Models Complex Immune Responses
Researchers at the Harvard Wyss Institute have created a microfluidic chip that contains lymphoid follicle-like structures, allowing them to model complex immune responses to various pathogens and vaccines. The breakthrough could let scientists to more comprehensively probe the complex workings of the immune system.
Lymphoid follicles are found in lymph nodes, and are the site of complex immune reactions which have not been easy to model in the lab to date. The new chip, called the LF chip, contains human B and T cells, and the Wyss researchers discovered that the cells would spontaneously form lymphoid follicle-like s...
Source: Medgadget - March 23, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Pathology Public Health Source Type: blogs
Whither Covid?
I recommend this Twitter thread by John Burn-Murdoch, as most Americans and their political leaders have apparently decided that the pandemic is over. It isn ' t, although here in the U.S. we are in a better place than we were a year ago. In a nutshell, new cases and hospitalizations are rising in much of the world, including much of Europe. This isn ' t so much because of loosened mitigation measures, but because of the emergence of a new variant, Omicron B.A2 which is evidently even more contagious than the original Omicron and perhaps a bit better at getting around existing immunity. It ' s just starting to show up...
Source: Stayin' Alive - March 18, 2022 Category: American Health Source Type: blogs
The (sort of, partial) Father mRNA Vaccines Who Now Spreads Vaccine Misinformation (Part 2)
By DAVID WARMFLASH, MD
This is part 2 of David Warmlash’s takedown of Robert W. Malone’s appearance (transcript) on the Rogan podcast. Part 1 is here
Menstruation and Fertility
Much more than the line about reproductive damage in the Wisconsin News clip that we used to open the story, Malone used the Rogan interview to dive more deeply into the topic, starting with:
…there’s a huge number of dysmenorrhea and menometrorrhagia…
By that, he meant excessive menstrual cramping and very heavy, often irregular, bleeding, which he followed up with:
…they DENY it…
Judging by other parts ...
Source: The Health Care Blog - March 18, 2022 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Health Policy antivaxxer COVID-19 vaccine David Warmflash Joe Rogan Robert Malone Source Type: blogs
Microfluidic Device for Quick and Accurate SARS-CoV-2 Testing
Researchers at the Institute of Photonic Sciences in Barcelona, Spain, have created a microfluidic chip that can detect the SARS-CoV-2 virus in less than 30 minutes, and with a similar level of accuracy as the current gold-standard test, PCR. The technology combines the speed of antigen tests with the accuracy of PCR and may be useful for point-of-care testing. The technique involves combining a few drops of saliva with fluorescent antibodies against the virus. Then, the saliva sample is passed through a microfluidic channel, where a laser illuminates bound fluorescent antibodies and an optical detector rapidly assesses if...
Source: Medgadget - March 1, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Public Health Source Type: blogs
‘Just Follow the Science’ Shows Some Improvement
Peter Van DorenDuring summer 2020 I wrote anessay about what science can and cannot do and the role it can play in public policy decisions including those pertaining to the COVID-19 pandemic. I concluded that science explains relationships between cause and effect: no more and no less. No normative conclusions about individual or collective decisions follow directly from science. Instead, costs, benefits, and other values properly enter both individual and collective decisions.I have writtenthreetimessince then about gradual recognition of this argument among medical professionals as well as journalists. I a...
Source: Cato-at-liberty - February 16, 2022 Category: American Health Authors: Peter Van Doren Source Type: blogs
Fight Aging! Newsletter, January 17th 2022
In conclusion, fibroblasts in monolayers cultured with soluble pentosidine and tridimensional in vitro skin constructs exposed to the combination of AGEs and UVA promote an inflammatory state and an alteration of the dermal compartment in relation to an elastosis-like environment. (Source: Fight Aging!)
Source: Fight Aging! - January 16, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
