What a Year! | Pandemic Teaching & More | A Reflection | TAPP 86
Discussions that matter. In our private space, we can have the vulnerability needed for authentic, deep discussions. Discussions not limited to a sentence or two at a time.No ads. No spam. No fake news. No thoughtless re-shares. Just plain old connection with others who do what you do!Privacy. The A&P Professor community has the connectivity of Facebook and Twitter, but the security of a private membership site. None of your information can be shared outside the community, so you can share what you like without it being re-shared to the world. Like your dean, for instance. In our community, you can share your frustrati...
Source: The A and P Professor - January 27, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
What a Year! | Pandemic Teaching & More | A Reflection | TAPP 86
Discussions that matter. In our private space, we can have the vulnerability needed for authentic, deep discussions. Discussions not limited to a sentence or two at a time.No ads. No spam. No fake news. No thoughtless re-shares. Just plain old connection with others who do what you do!Privacy. The A&P Professor community has the connectivity of Facebook and Twitter, but the security of a private membership site. None of your information can be shared outside the community, so you can share what you like without it being re-shared to the world. Like your dean, for instance. In our community, you can share your frustrati...
Source: The A and P Professor - January 27, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
A little less nervous about Covid
The rare and potentially lethal neurological disorder, Guillain-Barré syndrome, is not triggered by Covid nor by vaccination against Covid, recent research suggests.
There was concern during the early months of the Covid pandemic based on anecdotal evidence that there had been an increase in the incidence of a potentially lethal neurological disorder known as Guillain-Barré syndrome (GBS). In this disease, the body’s own immune system attacks peripheral nerves causing numbness, pain, and paralysis. It can be fatal if not treated promptly.
Pain and numbness often spread upwards from the soles of the feet or the hand...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 21, 2021 Category: Science Authors: David Bradley Tags: COVID-19 Source Type: blogs
Responding to Misinformation
By John Halamka and Paul CerratoThe singer/songwriter Paul Simon once penned the lyrics: A man hears what he wants to hear and disregards the rest (The Boxer). If that ’s the case, how do we respond to misinformation that contradicts the data/evidence guiding development of treatment and cures? If the only audience willing to read such articles are already critical thinkers, perhaps we are just preaching to the choir. And if by chance, a person who believes in controversial ideas does read articles based on real world evidence, will they consider them a one-sided discussion by the “medical-industrial es...
Source: Life as a Healthcare CIO - January 14, 2021 Category: Information Technology Source Type: blogs
Diminishing Religious Liberties: COVID Under the First Amendment
Daniel Figueroa (University of Massachusetts), Diminishing Religious Liberties: COVID Under the First Amendment, SSRN: The coronavirus has caused an unprecedented shutdown of biblical proportions. As the world manages a pandemic, of similarities of the 1918 Influenza, that has caused a... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - January 14, 2021 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
3 simple steps to jump-start your heart health this year
In 2020, the terrible toll of the COVID-19 pandemic largely overshadowed the affliction that remains the leading cause of death in this country: heart disease. In the United States last year, at least twice as many people died from cardiovascular causes as those who died from complications from SARS-CoV-2, the novel coronavirus.
While the challenges from the virus are new, experts have been studying heart disease for decades — and everyone can benefit from that knowledge. “The lifestyle habits that keep your heart healthy may also leave you less vulnerable to serious complications from infections such as COVID-19 and i...
Source: Harvard Health Blog - January 12, 2021 Category: Consumer Health News Authors: Julie Corliss Tags: Exercise and Fitness Health Healthy Eating Heart Health Source Type: blogs
Fight Aging! Newsletter, January 11th 2021
This study demonstrates the potential of a natural (o-Vanillin) and a synthetic (RG-7112) senolytic compounds to remove senescent IVD cells, decrease SASP factors release, reduce the inflammatory environment and enhance the IVD matrix production. Removal of senescent cells, using senolytics drugs, could lead to improved therapeutic interventions and ultimately decrease pain and a provide a better quality of life of patients living with intervertebral disc degeneration and low back pain.
From Ying Ann Chiao of Oklahoma Medical Research Foundation: Mitochondrial dysfunction plays a central role in aging and cardiovasc...
Source: Fight Aging! - January 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Frail Older Individuals Exhibit a Worse Response to Vaccination
Frailty is usually accompanied by greater immune dysfunction, given that chronic inflammation is a strong component of both immune aging and the various dysfunctions of frailty. Thus frail individuals exhibit a worse response to vaccinations intended to prevent infectious disease. This is unfortunate, as this is the population in greatest need of the defense of vaccination. This is illustrated every year by the toll of deaths due to influenza, and particularly this year by the ongoing COVID-19 pandemic. A great deal of effort goes into attempts to improve vaccine efficiency (Source: Fight Aging!)
Source: Fight Aging! - January 4, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, January 4th 2021
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - January 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Look Back at 2020: Progress Towards the Treatment of Aging as a Medical Condition
While I suspect that COVID-19 will feature prominently in most retrospectives on 2020, I'll say only a little on it. The data on mortality by year end, if taken at face value, continues to suggest that the outcome will fall at the higher end of the early estimates of a pandemic three to six times worse than a bad influenza year, ten times worse than a normal influenza year. The people who die are near entirely the old, the co-morbid, and the immunocompromised. They die because they are suffering the damage and dysfunction of aging. Yet the societal conversation and the actions of policy makers ignore this.
There is ...
Source: Fight Aging! - December 31, 2020 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
Last Christmas – a short story
Last Christmas by David Bradley (PDF/Kindle version here)
Funnily enough, it was four years to the day since the fourth variant had emerged. So, it was Christmas Day. Four years since the death toll passed 200 million. What a gift. Four years since the last dying embers of the theory of herd immunity had burned out and even the rich and the beyond-rich were suffering.
Four years. It’s hard to believe. What started as a very localised outbreak, with a mere handful of hospitalisations had quickly thrown the global community into panic and ultimately pandemic. The present that keeps on giving. Each genetic mutation unwrappi...
Source: David Bradley Sciencebase - Songs, Snaps, Science - December 29, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs
Last Christmas – a Xmas Gothic
Last Christmas by David Bradley (PDF/Kindle version here)
Funnily enough, it was four years to the day since the fourth variant had emerged. So, it was Christmas Day. Four years since the death toll passed 200 million. What a gift. Four years since the last dying embers of the theory of herd immunity had burned out and even the rich and the beyond-rich were suffering.
Four years. It’s hard to believe. What started as a very localised outbreak, with a mere handful of hospitalisations had quickly thrown the global community into panic and ultimately pandemic. The present that keeps on giving. Each genetic mutation unwrappi...
Source: David Bradley Sciencebase - Songs, Snaps, Science - December 29, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs
Fight Aging! Newsletter, December 28th 2020
In conclusion, our study demonstrated that the molecular processes of aging are relatively subtle in their progress, and the aging process of every tissue depends on the tissue's specialized function and environment. Hence, individual gene or process alone cannot be described as the key of aging in the whole organism.
Mouse Age Matters: How Age Affects the Murine Plasma Metabolome
A large part of metabolomics research relies on experiments involving mouse models, which are usually 6 to 20 weeks of age. However, in this age range mice undergo dramatic developmental changes. Even small age differences may l...
Source: Fight Aging! - December 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
ECMO – Extracorporeal membrane oxygenation
ECMO – extracorporeal membrane oxygenation
ECMO – Extracorporeal membrane oxygenation – has been in use for the past four decades to support persons who are unlikely to survive with mechanical ventilation. ECMO is used in both adult and pediatric practice, though in the initial years, use of ECMO was restricted to pediatric intensive care. The enthusiasm for use of ECMO in adults have been triggered by the beneficial effect noted during the last H1N1 influenza pandemic [1]. In contrast from cardiopulmonary bypass which is used for a short period during cardiac surgery, ECMO is used to support for a ...
Source: Cardiophile MD - December 26, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiac Surgery Source Type: blogs
Data for COVID-19 Mortality in Older People in the US
The general consensus on mortality due to COVID-19 is that it falls most heavily on people who are more impacted by aging: poor immune function when it comes to defense against pathogens; high levels of chronic inflammation that create a greater susceptibility to the way in which SARS-CoV-2 kills people; existing chronic disease; and a mortality rate that is already high even setting aside the pandemic. When younger people die due to the virus, in much smaller numbers, it is where they share these characteristics of inflammation, deficient immune systems, and chronic disease. This level of morbidity is unusual in younger i...
Source: Fight Aging! - December 23, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
