Perception of herbs use in treating diabetes among patients attending specialized polyclinics of National Guard Health Affairs, Jeddah
CONCLUSION: This study concluded that herbs are commonly used among diabetic patients and the majority of patients perceive herbs as a cofactor in controlling diabetes.PMID:37091011 | PMC:PMC10114559 | DOI:10.4103/jfmpc.jfmpc_1155_22 (Source: Primary Care)
Source: Primary Care - April 24, 2023 Category: Primary Care Authors: Mahmoud A Alzahrani Khulood A Alsiary Muhammad A Khan Adeeb Bushnaq Bassam Alzahrani Marwan Salama Nawaf S Alamri Source Type: research

[ASAP] Biosurfactant Derived from Fenugreek Seeds and Its Impact on Wettability Alteration, Oil Recovery, and Effluent Treatment of a Rock System of Mixed Composition
Energy& FuelsDOI: 10.1021/acs.energyfuels.3c00105 (Source: Energy and Fuels)
Source: Energy and Fuels - April 17, 2023 Category: Chemistry Authors: Alpana Singh, Tushar Sharma, Ravi Shankar Kumar, and Muhammad Arif Source Type: research

Effects of < em > Trigonella foenum graecum < /em > (Fenugreek) on Rheumatoid Arthritis: A Systematic Review
CONCLUSION: Current review provides potent evidences about the efficacy of fenugreek in RA and elucidates the significance of more clinical investigations.Highlights*Fenugreek had favorable effects in rheumatoid arthritis and could control this disease via attenuating inflammation, suppressing oxidative stress, and displaying anti-arthritic activity.PMID:37039783 | DOI:10.1080/08923973.2023.2202298 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - April 11, 2023 Category: Allergy & Immunology Authors: Zeinab Faghfoori Zeinab Javadivala Yeganeh Khalili Aida Malek Mahdavi Source Type: research

Effects of < em > Trigonella foenum graecum < /em > (fenugreek) on rheumatoid arthritis: a systematic review
CONCLUSION: Current review provides potent evidences about the efficacy of fenugreek in RA and elucidates the significance of more clinical investigations. HighlightsFenugreek had favorable effects in rheumatoid arthritis and could control this disease via attenuating inflammation, suppressing oxidative stress, and displaying anti-arthritic activity.PMID:37039783 | DOI:10.1080/08923973.2023.2202298 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - April 11, 2023 Category: Allergy & Immunology Authors: Zeinab Faghfoori Zeinab Javadivala Yeganeh Khalili Aida Malek Mahdavi Source Type: research

Ultrasonic-assisted extraction of fenugreek flavonoids and its geographical-based comparative evaluation using green UHPLC-DAD analysis
CONCLUSION: The samples were effectively evaluated and standardized in terms of flavonoid amount suggesting a significant variation in fenugreek quality.PMID:37031535 | DOI:10.1016/j.ultsonch.2023.106382 (Source: Ultrasonics Sonochemistry)
Source: Ultrasonics Sonochemistry - April 9, 2023 Category: Chemistry Authors: Rizwan Ahmad Aljawharah Alqathama Mohammed Aldholmi Muhammad Riaz Sayed M Eldin Mohammad Mahtab Alam Shaimaa A M Abdelmohsen Source Type: research

Ultrasonic-assisted extraction of fenugreek flavonoids and its geographical-based comparative evaluation using green UHPLC-DAD analysis
CONCLUSION: The samples were effectively evaluated and standardized in terms of flavonoid amount suggesting a significant variation in fenugreek quality.PMID:37031535 | DOI:10.1016/j.ultsonch.2023.106382 (Source: Ultrasonics Sonochemistry)
Source: Ultrasonics Sonochemistry - April 9, 2023 Category: Chemistry Authors: Rizwan Ahmad Aljawharah Alqathama Mohammed Aldholmi Muhammad Riaz Sayed M Eldin Mohammad Mahtab Alam Shaimaa A M Abdelmohsen Source Type: research

Ultrasonic-assisted extraction of fenugreek flavonoids and its geographical-based comparative evaluation using green UHPLC-DAD analysis
CONCLUSION: The samples were effectively evaluated and standardized in terms of flavonoid amount suggesting a significant variation in fenugreek quality.PMID:37031535 | DOI:10.1016/j.ultsonch.2023.106382 (Source: Ultrasonics Sonochemistry)
Source: Ultrasonics Sonochemistry - April 9, 2023 Category: Chemistry Authors: Rizwan Ahmad Aljawharah Alqathama Mohammed Aldholmi Muhammad Riaz Sayed M Eldin Mohammad Mahtab Alam Shaimaa A M Abdelmohsen Source Type: research

Diosgenin reduces bone loss through the regulation of gut microbiota in ovariectomized rats
This study aimed to investigate the effects of DIO on the gut microbiota (GM) of ovariectomized (OVX) osteoporotic rats. Female Sprague-Dawley rats were randomly divided into sham operation (sham + vehicle group) or ovariectomy. For 12 weeks, OVX rats were treated using a vehicle (OVX + vehicle group) and DIO (OVX + DIO group). Subsequently, ELISA was conducted to determine serum estradiol levels, micro-CT scanning was performed to evaluate bone quality, and feces were collected for metagenomics sequencing to examine the structure and function of GM. Raw reads were filtered to remove chimera sequences. Operational taxonomi...
Source: Gene - March 31, 2023 Category: Genetics & Stem Cells Authors: Changheng Song Yujie Ma Yuhan Wang Pei Li Yanjing Chen Haixia Liu Zhiguo Zhang Source Type: research

Diosgenin reduces bone loss through the regulation of gut microbiota in ovariectomized rats
This study aimed to investigate the effects of DIO on the gut microbiota (GM) of ovariectomized (OVX) osteoporotic rats. Female Sprague-Dawley rats were randomly divided into sham operation (sham + vehicle group) or ovariectomy. For 12 weeks, OVX rats were treated using a vehicle (OVX + vehicle group) and DIO (OVX + DIO group). Subsequently, ELISA was conducted to determine serum estradiol levels, micro-CT scanning was performed to evaluate bone quality, and feces were collected for metagenomics sequencing to examine the structure and function of GM. Raw reads were filtered to remove chimera sequences. Operational taxonomi...
Source: Gene - March 31, 2023 Category: Genetics & Stem Cells Authors: Changheng Song Yujie Ma Yuhan Wang Pei Li Yanjing Chen Haixia Liu Zhiguo Zhang Source Type: research

Anticancer Activity of Diosgenin and Its Molecular Mechanism
This article aims to provide an overview of thein vivo, in vitro, and clinical studies reporting the diosgenin ’s anticancer effects. Preclinical studies have shown promising effects of diosgenin on inhibiting tumor cell proliferation and growth, promoting apoptosis, inducing differentiation and autophagy, inhibiting tumor cell metastasis and invasion, blocking cell cycle, regulating immunity and improving gut microbiome. Clinical investigations have revealed clinical dosage and safety property of diosgenin. Furthermore, in order to improve the biological activity and bioavailability of diosgenin, this review focuses on ...
Source: Chinese Journal of Integrative Medicine - March 20, 2023 Category: Internal Medicine Source Type: research