Cancers, Vol. 16, Pages 1611: An Overview of the Spices Used for the Prevention and Potential Treatment of Gastric Cancer
We present the potential molecular mechanisms responsible for the effectivity of a given seasoning substance and their impact on GC cells. We discuss their potential effects on proliferation, apoptosis, and migration. For most of the spices discussed, we also outline the unavailability and side effects of their use. (Source: Cancers)
Source: Cancers - April 22, 2024 Category: Cancer & Oncology Authors: Katarzyna Kostelecka Łukasz Bryliński Olga Komar Justyna Michalczyk Agata Mi łosz Jan Bi łogras Filip Woli ński Alicja Forma Jacek Baj Tags: Review Source Type: research

Transcriptomic data reveals the dynamics of terpenoids biosynthetic pathway of fenugreek
Medicinal plants are rich sources for treating various diseases due their bioactive secondary metabolites. Fenugreek (Trigonella foenum-graecum) is one of the medicinal plants traditionally used in human nutritio... (Source: BMC Genomics)
Source: BMC Genomics - April 22, 2024 Category: Genetics & Stem Cells Authors: Sara Lamei Javan, Arman Beyraghdar Kashkooli, AbdolAli Shojaeiyan and Sina Majidian Tags: Research Source Type: research

Withania somnifera and Trigonella foenum-graecum as ingredients of testosterone-boosting supplements: Possible clinical implications
Adv Clin Exp Med. 2024 Apr 17. doi: 10.17219/acem/185743. Online ahead of print.ABSTRACTThis narrative review provides an overview of scientific studies on dietary supplements that may affect circulating testosterone (T) levels to explore which substances are scientifically proven to increase T concentration. We also review the scientific literature for their potential mechanisms and laboratory test changes triggered by their use. Based on the analysis of existing data on substances used to increase endogenous T levels, especially double-blind placebo-controlled randomized clinical trials, we selected 2 herbal extracts wit...
Source: Adv Data - April 17, 2024 Category: Epidemiology Authors: Monika Skrzypiec-Spring Andrzej Pokrywka Justyna Kuliczkowska-P łaksej Adam Szel ąg Marek Bolanowski Source Type: research

Withania somnifera and Trigonella foenum-graecum as ingredients of testosterone-boosting supplements: Possible clinical implications
Adv Clin Exp Med. 2024 Apr 17. doi: 10.17219/acem/185743. Online ahead of print.ABSTRACTThis narrative review provides an overview of scientific studies on dietary supplements that may affect circulating testosterone (T) levels to explore which substances are scientifically proven to increase T concentration. We also review the scientific literature for their potential mechanisms and laboratory test changes triggered by their use. Based on the analysis of existing data on substances used to increase endogenous T levels, especially double-blind placebo-controlled randomized clinical trials, we selected 2 herbal extracts wit...
Source: Adv Data - April 17, 2024 Category: Epidemiology Authors: Monika Skrzypiec-Spring Andrzej Pokrywka Justyna Kuliczkowska-P łaksej Adam Szel ąg Marek Bolanowski Source Type: research

Variability in genome size of Trigonella foenum-graecum, Trigonella corniculata and Trigonella caerulea as estimated by flow cytometry indicates complex evolutionary history of fenugreek
CONCLUSIONS: The differences observed in the genome sizes of the three species provide conclusive evidence of their genetic divergence. Additionally, the information about the genome size would provide an impetus to the structural and functional genomics-based research in this crop.PMID:38578370 | DOI:10.1007/s11033-024-09417-5 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 5, 2024 Category: Molecular Biology Authors: Sheel Yadav Ratna Kumari Parimalan Rangan Ambika Baldev Gaikwad Source Type: research

Variability in genome size of Trigonella foenum-graecum, Trigonella corniculata and Trigonella caerulea as estimated by flow cytometry indicates complex evolutionary history of fenugreek
CONCLUSIONS: The differences observed in the genome sizes of the three species provide conclusive evidence of their genetic divergence. Additionally, the information about the genome size would provide an impetus to the structural and functional genomics-based research in this crop.PMID:38578370 | DOI:10.1007/s11033-024-09417-5 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 5, 2024 Category: Molecular Biology Authors: Sheel Yadav Ratna Kumari Parimalan Rangan Ambika Baldev Gaikwad Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research

Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research