Fight Aging! Newsletter, February 26th 2024
In conclusion, mTORC1 signaling contributes to the ISC fate decision, enabling regional control of intestinal cell differentiation in response to nutrition. « Back to Top Reviewing the Development of Senotherapeutics to Treat Aging https://www.fightaging.org/archives/2024/02/reviewing-the-development-of-senotherapeutics-to-treat-aging/ Senescent cells accumulate with age and contribute meaningfully to chronic inflammation and degenerative aging. Destroying these cells produces rapid and sizable reversal of age-related diseases in mice, demonstrating that the presence of senescence cells ...
Source: Fight Aging! - February 25, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Why ICDs are less effective in Non Ischemic DCM ?
We wish, our understanding about cardiac contractile physiology is deep and nearly complete. Heart is an irreversibly coupled electro-mechanical organ , right from the fetal days until the final heart beat. In myocardial pathology, the genesis and sustainability of ventricular arrhythmia are intricately related to the degree of LV dysfunction of any cause. SCD is the leading cause of mortality in heart failure. Tackling SCD was in God’s domain, until the brilliance of Dr. Michel Mirowski shrunk the defibrillator and implanted it under the chest in 1980. (Dr. MM’s s a unique and inspiring story, from Poland a...
Source: Dr.S.Venkatesan MD - February 20, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized crt device crt-p vs crt-d danish trial ischemic dcm madit trial non ischemic dcm Source Type: blogs

To What Degree is Alzheimer's Disease a Modern Phenomenon?
Here find an interesting commentary on what might be gleaned of the prevalence of Alzheimer's disease in antiquity from the body of ancient writings on the topic of aging, memory, and health. The consensus is that Alzheimer's disease is a creation of modernity, some combination of a longer life expectancy for a greater fraction of the population coupled with increased calorie intake and less active lives. Yet unlike type 2 diabetes, risk of Alzheimer's risk doesn't correlate well with the usual suspect lifestyle choices that raise the risk of age-related disease and lower life expectancy. This line of thinking has l...
Source: Fight Aging! - February 19, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Purdue Pharma, The Sackler Family, and The U.S. Opioid Epidemic
Lawrence J. Trautman (Prairie View A&M University), Larry D. Foster, II (Prairie View A&M University), Purdue Pharma, The Sackler Family, and The U.S. Opioid Epidemic (2023): During recent years, the continued outbreak of addiction in the United States has reached... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - February 13, 2024 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

The opioid addiction epidemic and its impact on health care costs
The opioid addiction crisis has escalated into a formidable challenge within the U.S. health care system, causing widespread devastation. The opioid epidemic has not only devastated communities and individual lives but has also inflicted a substantial economic toll on the health care system. The opioid epidemic has led to a surge in health care costs, Read more… The opioid addiction epidemic and its impact on health care costs originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 5, 2024 Category: General Medicine Authors: Tags: Conditions Emergency Medicine Pain Management Source Type: blogs

Vita Health Announces $22.5M Series A Funding Round
Supports National Expansion of Critical Mission to Address Suicide Epidemic Vita Health, the first provider of clinically validated suicide prevention through innovative care management, announced today the close of a $22.5M Series A funding round. The funding will support the rapid expansion of life-saving services targeting youth and adults nationwide. The Vita behavioral health care pathways are based on the founding team’s successful clinical trials published in JAMA, The American Journal of Psychiatry, and thousands of patient encounters demonstrating reductions in suicide attempts by more than 60% and deaths by up ...
Source: EMR and HIPAA - January 26, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Athyrium Capital Management Connecticut Innovations CU Healthcare Innovation Fund CVS Health Ventures Flare Capital Partners Health IT Funding Health IT Fundings Health IT Investment HopeLab LFE Capita Source Type: blogs

How one family ’ s hero ended a pandemic [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Shan Liu, an emergency physician and co-author of Masked Hero: How Wu-Lien Teh Invented the Mask and Ended an Epidemic. Discover the journey of Wu Lien-teh, Shan’s great-grandfather, who played a pivotal role in ending a devastating plague in China in 1911. We’ll Read more… How one family’s hero ended a pandemic [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 26, 2024 Category: General Medicine Authors: Tags: Podcast COVID Infectious Disease Source Type: blogs

Zombie Viruses of the Permafrost
By KIM BELLARD We’ve had some cold weather here lately, as has much of the nation. Not necessarily record-breaking, but uncomfortable for millions of people. It’s the kind of weather that causes climate change skeptics to sneer “where’s the global warming now?” This despite 2023 being the warmest year on record — “by far” — and the fact that the ten warmest years since 1850 have all been in the last decade, according to NOAA. One of the parts of the globe warming the fastest is the Arctic, which is warming four times as fast as the rest of the planet. That sounds like good news if you run a ...
Source: The Health Care Blog - January 24, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Climate Change Kim Bellard Viruses Source Type: blogs

Healthcare AI – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  In fact, we got so many that we had to narrow them down to just the best and most interesting.  Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. All of this year’s 2024 health IT predictions (updated as they’re shared): John and ...
Source: EMR and HIPAA - January 19, 2024 Category: Information Technology Authors: John Lynn Tags: AI/Machine Learning Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System LTPAC 2024 Health IT Predictions Authenticx Availity Cara Brant care.ai Carenet Health Chakri Toleti Christopher Rogers Source Type: blogs

Health IT – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  In fact, we got so many that we had to narrow them down to just the best and most interesting.  Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. All of this year’s 2024 health IT predictions (updated as they’re shared): John and ...
Source: EMR and HIPAA - January 18, 2024 Category: Information Technology Authors: John Lynn Tags: Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System LTPAC 2024 Health IT Predictions Aasim Saeed Amenities Health Andrew Harding Ankit Gupta Anthony Hare Ash Wellness Availity Bicycle Health Source Type: blogs

Patients – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  In fact, we got so many that we had to narrow them down to just the best and most interesting.  Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. All of this year’s 2024 health IT predictions (updated as they’re shared): John and ...
Source: EMR and HIPAA - January 16, 2024 Category: Information Technology Authors: John Lynn Tags: Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System LTPAC 2024 Health IT Predictions ABOUT ABOUT Healthcare Amanda Bury Amit Kapoor Cedar Chris Blackley Christian Hardahl Clarify Health Clin Source Type: blogs

knownwell Raises $20M Series A From A16Z to Scale the First Patient-Centered Healthcare Home For Those With Overweight and Obesity
Building on This Mission, the Company is Launching an Adolescent Metabolic Health Program to Combat Rising Child Obesity Rates knownwell, an in-person and virtual, weight-inclusive primary care and metabolic health company, today announced that it has raised a $20 million Series A funding round led by a16z with participation from existing investors including Flare Capital Partners. This brings knownwell’s total funding to $24.5 million and highlights a growing demand for weight-inclusive care companies focusing on whole-person treatment approaches to obesity beyond just short-term approaches like GLP-1 utilization organi...
Source: EMR and HIPAA - January 15, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT a16z Brooke Boyarsky Pratt Dr. Angela Fitch Flare Capital Partners Health IT Funding Health IT Fundings Health IT Investment knownwell Vineeta Agarwala Source Type: blogs

CMV: the silent epidemic expectant mothers need to know about [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Megan Nix, a writer and author of Remedies for Sorrow: An Extraordinary Child, a Secret Kept from Pregnant Women, and a Mother’s Pursuit of the Truth. Megan shares her deeply personal journey and research into congenital CMV, shedding light on the importance of Read more… CMV: the silent epidemic expectant mothers need to know about [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 3, 2024 Category: General Medicine Authors: Tags: Podcast Infectious Disease Source Type: blogs

AI enforcement in health care: Unpacking the DEA ’ s approach to the opioid epidemic
In 2017, Attorney General Jeff Sessions became convinced that the opioid crisis was not the fault of cartels smuggling fentanyl across porous American checkpoints. And it wasn’t due to pharmaceutical companies corrupting drug approval officials and DEA administrators by hiring them as consultants after making decisions in the company’s favor. No. The opioid crisis was Read more… AI enforcement in health care: Unpacking the DEA’s approach to the opioid epidemic originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 2, 2024 Category: General Medicine Authors: Tags: Meds Pain Management Source Type: blogs

Lifestyle Matters: Let ’s optimize cognition, health and life in 2024
Welcome to a new edition of SharpBrains e‑newsletter, featuring fascinating research findings on lifestyle, protective brain structures, Internet access, mental health, brain imaging, and more. #1. Lifestyle matters: What we can do in 2024 to optimize cognition and life, delaying cognitive problems even dementia “Actor Chris Hemsworth…watched his grandfather live with Alzheimer’s and is making lifestyle changes after learning he has two copies of the APOE4 gene. This gene is a risk factor for Alzheimer’s, and having two copies significantly increases his risk of developing the same condition.” (Smart move reg...
Source: SharpBrains - December 27, 2023 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health SharpBrains Monthly eNewsletter Technology & Innovation adhd Alzheimer’s APOE4 gene Brain-Imaging dementia symptoms frontotemporal dementia lifestyle Neurophet Source Type: blogs