Comparison of intermittent screening (using ultra-sensitive malaria rapid diagnostic test) and treatment (using a newly registered antimalarial pyronaridine-artesunate —PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas: ULTRAPYRAPREG
This study aims to compare the non-inferiority of ISTp using us-RDTs and Pyramax ® versus IPTp-SP on malaria in pregnancy through a randomized clinical trial performed in Kisenso, Kinshasa, the Democratic Republic of the Congo, a malaria perennial transmission area.DiscussionThe results will be essential for the National Malaria Control Program to update the malaria prevention policy in pregnant women in the Democratic Republic of the Congo.Trial registrationClinicalTrials.gov NCT04783051 (Source: Trials)
Source: Trials - November 28, 2022 Category: Research Source Type: clinical trials
Atea Pharmaceuticals Announces U.S. FDA Fast Track Designation Granted to AT-752 for Treatment of Dengue
Dengue is the most prevalent mosquito-borne viral disease; endemic to 100 countries worldwide, with more than half the world’s populations at-risk
AT-752 is a novel, orally administered, direct-acting antiviral in Phase 2 development for... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - September 26, 2022 Category: Pharmaceuticals Source Type: clinical trials
Pfizer and Valneva Initiate Phase 3 Study of Lyme Disease Vaccine Candidate VLA15
Approximately 6,000 participants 5 years of age and older will be enrolled in Lyme disease-endemic regions in Europe and the U.S.
NEW YORK& SAINT-HERBLAIN, France--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) and Valneva SE (Nasdaq: VALN;... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - August 8, 2022 Category: Pharmaceuticals Source Type: clinical trials
Triage UltraSound in Tb Endemic Regions
Conditions: Tuberculosis; Lower Resp Tract Infection; Pneumonia Intervention: Diagnostic Test: POCUS Sponsors: Centre Hospitalier Universitaire Vaudois; National University Hospital for tuberculosis, Cotonou, Benin; Ecole Polytechnique Fédérale de Lausanne; University of Witwatersrand, South Africa; National University Hospital (CNHU point G), Bamako, Mali Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 21, 2022 Category: Research Source Type: clinical trials
