History of learning disorders is associated with worse cognitive and functional outcomes in schizophrenia: results from the multicentric FACE-SZ cross-sectional dataset
AbstractSchizophrenia is associated with early neurodevelopmental disorders, including most frequently learning disorders (LD), among them dyslexia and dyspraxia. Despite the demonstrated links between schizophrenia and LD, specific clinical patterns of the schizophrenia with a history of LD subgroup remain unknown. The aim of the present study was to investigate cognitive impairment, symptoms and functional outcome associated with a history of LD in a large cross-sectional, multicentric, sample of schizophrenia subjects. 492 community-dwelling subjects with schizophrenia (75.6% male, mean age 30.8 years) were consecutiv...
Source: European Archives of Psychiatry and Clinical Neuroscience - December 30, 2022 Category: Neuroscience Source Type: research
IJERPH, Vol. 19, Pages 5509: The Role of Motor Coordination, ADHD-Related Characteristics and Temperament among Mothers and Infants in Exclusive Breastfeeding: A Cohort Prospective Study
it Bart
Although exclusive breastfeeding is recommended for the first 6 months of life, breastfeeding rates are low. Motor skills and ADHD-related characteristics have not yet been examined as breastfeeding barriers. The aim of this study was to explore whether mothers’ and infants’ motor skills, mothers’ ADHD-related characteristics and infants’ temperament are associated with exclusive breastfeeding at 6 months after birth. Participants were 164 mothers and their infants recruited 2 days after birth. Mothers completed a demographic and delivery information quest...
Source: International Journal of Environmental Research and Public Health - May 1, 2022 Category: Environmental Health Authors: Adi Freund-Azaria Tami Bar-Shalita Rivka Regev Orit Bart Tags: Article Source Type: research
Novel Biallelic Variant in the BRAT1 Gene Caused Nonprogressive Cerebellar Ataxia Syndrome
Recessive mutations in BRAT1 cause lethal neonatal rigidity and multifocal seizure syndrome (RMFSL), a phenotype characterized by neonatal microcephaly, hypertonia, and refractory epilepsy with premature death. Recently, attenuated disease variants have been described, suggesting that a wider clinical spectrum of BRAT1-associated neurodegeneration exists than was previously thought. Here, we reported a 10-year-old girl with severe intellectual disability, rigidity, ataxia or dyspraxia, and cerebellar atrophy on brain MRI; two BRAT1 variants in the trans configuration [c.1014A > C (p.Pro338 = ); c.706delC (p.Leu236Cysfs*...
Source: Frontiers in Genetics - March 10, 2022 Category: Genetics & Stem Cells Source Type: research
Prenatal Diagnosis and Neurodevelopmental Outcome in Isolated Cerebellar Hypoplasia of Suspected Hemorrhagic Etiology: a Retrospective Cohort Study
Cerebellum. 2021 Nov 20. doi: 10.1007/s12311-021-01341-9. Online ahead of print.ABSTRACTData about the neurological prognosis of isolated cerebellar hypoplasia in utero are scant and inconsistent. In this monocentric retrospective study, we describe the neurodevelopmental outcomes in a series of children with isolated cerebellar hypoplasia of presumably hemorrhagic origin prenatally detected with fetal magnetic resonance imaging (fMRI). We retrospectively reviewed the charts of all the pregnant women who were referred for a neurological consultation, diagnosed with fetal encephalic malformation/disruption between 2010 and ...
Source: Cerebellum - November 20, 2021 Category: Neuroscience Authors: Barbara Scelsa Gianni Cutillo Mariano Matteo Lanna Andrea Righini Marina Antonella Balestriero Valeria Brazzoduro Stefania Zambrano Cecilia Parazzini Enrico Alfei Mariangela Rustico Source Type: research
Prenatal Diagnosis and Neurodevelopmental Outcome in Isolated Cerebellar Hypoplasia of Suspected Hemorrhagic Etiology: a Retrospective Cohort Study
Cerebellum. 2021 Nov 20. doi: 10.1007/s12311-021-01341-9. Online ahead of print.ABSTRACTData about the neurological prognosis of isolated cerebellar hypoplasia in utero are scant and inconsistent. In this monocentric retrospective study, we describe the neurodevelopmental outcomes in a series of children with isolated cerebellar hypoplasia of presumably hemorrhagic origin prenatally detected with fetal magnetic resonance imaging (fMRI). We retrospectively reviewed the charts of all the pregnant women who were referred for a neurological consultation, diagnosed with fetal encephalic malformation/disruption between 2010 and ...
Source: Cerebellum - November 20, 2021 Category: Neuroscience Authors: Barbara Scelsa Gianni Cutillo Mariano Matteo Lanna Andrea Righini Marina Antonella Balestriero Valeria Brazzoduro Stefania Zambrano Cecilia Parazzini Enrico Alfei Mariangela Rustico Source Type: research
Prenatal Diagnosis and Neurodevelopmental Outcome in Isolated Cerebellar Hypoplasia of Suspected Hemorrhagic Etiology: a Retrospective Cohort Study
Cerebellum. 2021 Nov 20. doi: 10.1007/s12311-021-01341-9. Online ahead of print.ABSTRACTData about the neurological prognosis of isolated cerebellar hypoplasia in utero are scant and inconsistent. In this monocentric retrospective study, we describe the neurodevelopmental outcomes in a series of children with isolated cerebellar hypoplasia of presumably hemorrhagic origin prenatally detected with fetal magnetic resonance imaging (fMRI). We retrospectively reviewed the charts of all the pregnant women who were referred for a neurological consultation, diagnosed with fetal encephalic malformation/disruption between 2010 and ...
Source: Cerebellum - November 20, 2021 Category: Neuroscience Authors: Barbara Scelsa Gianni Cutillo Mariano Matteo Lanna Andrea Righini Marina Antonella Balestriero Valeria Brazzoduro Stefania Zambrano Cecilia Parazzini Enrico Alfei Mariangela Rustico Source Type: research
Prenatal Diagnosis and Neurodevelopmental Outcome in Isolated Cerebellar Hypoplasia of Suspected Hemorrhagic Etiology: a Retrospective Cohort Study
Cerebellum. 2021 Nov 20. doi: 10.1007/s12311-021-01341-9. Online ahead of print.ABSTRACTData about the neurological prognosis of isolated cerebellar hypoplasia in utero are scant and inconsistent. In this monocentric retrospective study, we describe the neurodevelopmental outcomes in a series of children with isolated cerebellar hypoplasia of presumably hemorrhagic origin prenatally detected with fetal magnetic resonance imaging (fMRI). We retrospectively reviewed the charts of all the pregnant women who were referred for a neurological consultation, diagnosed with fetal encephalic malformation/disruption between 2010 and ...
Source: Cerebellum - November 20, 2021 Category: Neuroscience Authors: Barbara Scelsa Gianni Cutillo Mariano Matteo Lanna Andrea Righini Marina Antonella Balestriero Valeria Brazzoduro Stefania Zambrano Cecilia Parazzini Enrico Alfei Mariangela Rustico Source Type: research
Prenatal Diagnosis and Neurodevelopmental Outcome in Isolated Cerebellar Hypoplasia of Suspected Hemorrhagic Etiology: a Retrospective Cohort Study
AbstractData about the neurological prognosis of isolated cerebellar hypoplasia in utero are scant and inconsistent. In this monocentric retrospective study, we describe the neurodevelopmental outcomes in a series of children with isolated cerebellar hypoplasia of presumably hemorrhagic origin prenatally detected with fetal magnetic resonance imaging (fMRI). We retrospectively reviewed the charts of all the pregnant women who were referred for a neurological consultation, diagnosed with fetal encephalic malformation/disruption between 2010 and 2020 in the Fetal Therapy Unit of our institution. Fetal MRI (fMRI) was performe...
Source: The Cerebellum - November 20, 2021 Category: Neurology Source Type: research
Early diagnosis of the learning disabilities in kids using a computer game-based solution
Disabil Rehabil Assist Technol. 2021 Nov 16:1-9. doi: 10.1080/17483107.2021.2003454. Online ahead of print.ABSTRACTPURPOSE: Learning disabilities or learning disorders are umbrella terms used for wide variety of learning problems like Dyslexia, Dyscalculia, Dysgraphia, and Dyspraxia. These disabilities are due to the neurological disorders which affects brain functions. Early diagnosis of these disabilities in kids from age 3 to 6 will help to start early medical treatments and get them back to the normal condition.MATERIAL AND METHOD: we developed a software-based Learning Disability Evaluation Kit called YALU with comput...
Source: Disability and Rehabilitation. Assistive Technology. - November 16, 2021 Category: Rehabilitation Authors: N R Samarasinghe A H M G B Abeyasinghe Source Type: research
Predictive value of brain MRI at term-equivalent age in extremely preterm children on neurodevelopmental outcome at school-age
This study ’s objective was to correlate the abnormalities in brain MRIs performed at corrected-term age for minor or moderate neurocognitive disorders in children school-age born extremely premature (EPT) and without serious sequelae such as autism, cerebral palsy, mental impairment. Data were issued from a cross-sectional multicenter study (GP-Qol study, number NCT01675726). Clinical examination and psychometric assessments were performed when the children were between 7 and 10 years old during a day-long evaluation. Term-equivalent age brain MRIs on EPT were analyzed with a standardized scoring sys tem. There were 11...
Source: Brain Imaging and Behavior - October 18, 2021 Category: Neurology Source Type: research
IJERPH, Vol. 18, Pages 9965: Prenatal Exposure to Diethylstilbestrol and Multigenerational Psychiatric Disorders: An Informative Family
Conclusions: To our knowledge, the high prevalence of psychiatric disorders of various severities in two, and likely three generations, including DES-free pregnancies and DES-exposed pregnancies from the same family, has never been reported. This work strengthens the hypothesis that in utero exposure to DES contributes to the pathogenesis of psychiatric disorders. It also highlights a multigenerational, and possibly transgenerational, effect of DES in neurodevelopment and psychiatric disorders. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - September 22, 2021 Category: Environmental Health Authors: Marie-Odile Soyer-Gobillard Laura Gaspari Fran çoise Paris Nicolas Kalfa Samir Hamamah Philippe Courtet Charles Sultan Tags: Case Report Source Type: research
IJERPH, Vol. 18, Pages 9344: The Impact of the COVID-19 Pandemic on Students ’ Mental Health and Sleep in Saudi Arabia
Conclusion: This study has provided evidence that a lower level of psychological resilience and insomnia were associated with mental health problems among undergraduate students in Saudi Arabia, thus enhancing psychological resilience and interventions to support sleep and mental health are vital to support student well-being outcomes throughout the pandemic. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - September 4, 2021 Category: Environmental Health Authors: Azizah Alyoubi Elizabeth J. Halstead Zoe Zambelli Dagmara Dimitriou Tags: Article Source Type: research
