'Street valium' deaths prompt public health warning
A drug that's 10 times more toxic than Valium and is often mixed with powerful opioids has killed at least five people this year in Ontario, and public health officials worry there may be more deaths. (Source: CBC | Health)
Source: CBC | Health - October 17, 2019 Category: Consumer Health News Tags: News/Canada/Ottawa Source Type: news
‘Sticky’ gene may help Valium calm nerves
NIH mouse study could prompt scientists to rethink how benzodiazepines work. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - October 10, 2019 Category: American Health Source Type: news
Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions
The function and pharmacology of -aminobutyric acid type A receptors (GABAARs) are of great physiological and clinical importance and have long been thought to be determined by the channel pore–forming subunits. We discovered that Shisa7, a single-passing transmembrane protein, localizes at GABAergic inhibitory synapses and interacts with GABAARs. Shisa7 controls receptor abundance at synapses and speeds up the channel deactivation kinetics. Shisa7 also potently enhances the action of diazepam, a classic benzodiazepine, on GABAARs. Genetic deletion of Shisa7 selectively impairs GABAergic transmission and diminishes t...
Source: ScienceNOW - October 9, 2019 Category: Science Authors: Han, W., Li, J., Pelkey, K. A., Pandey, S., Chen, X., Wang, Y.-X., Wu, K., Ge, L., Li, T., Castellano, D., Liu, C., Wu, L.-G., Petralia, R. S., Lynch, J. W., McBain, C. J., Lu, W. Tags: Neuroscience reports Source Type: news
Houston TX Man Sentenced to 27 Months for Shipping Misbranded Prescription Drugs to Oldham County
Dhaval Jerambhai Dholaria, Houston TX, zolpidem tartrate, Ambien, Schedule IV controlled substance, tramadol, opioid, diazepam, Valium, zolpidem tartrate, clonazepam, Klonopin, Soma, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - October 9, 2019 Category: Medical Law Authors: DOJ Source Type: news
Emergent lands $20M contract to develop chemical weapon antidote
Gaithersburg ’s Emergent BioSolutions Inc. just added another task to its ever-growing to-do list: Develop a device to stop seizures caused by chemical weapons.
The company, which has two manufacturing sites in Baltimore, has secured about $20 million from the Department of Defense to design an auto-injector — a shot that can be given easily without medical training — to administer seizure drug diazepam, Emergent (NYSE: EBS) announced Thursday.
The product would reverse the effects of nerve… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 27, 2019 Category: Pharmaceuticals Authors: Sara Gilgore Source Type: news
Dishing out more drugs won ’t stop the pain. Doctors need new tools | Ann Robinson
As a GP, I know opioids have their place. But we shouldn ’t be complacent about a US-style crisis happening in BritainGrowing concern about the prescription of drugs that cause dependence has been backed up by a recent report from Public Health England (PHE). The agencydiscovered that in 2017-18, 13% of adults in England received at least one prescription for opioids such as morphine or oxycodone (although this represented a slight downturn in prescribing after a long upward trend). Other drug classes were implicated too, with 25% of adults prescribed one or more of the following drugs: benzodiazepines (such as Valium), ...
Source: Guardian Unlimited Science - September 15, 2019 Category: Science Authors: Ann Robinson Tags: Opioids GPs NHS Doctors Health Society Drugs policy Politics Science UK news Source Type: news
Houston, TX Man Pleads Guilty to Mailing Misbranded Prescription Drugs to Oldham County
Dhaval Jerambhai Dholaria, Houston, Texas, zolpidem tartrate, Ambien, Oldham County, Kentucky, India, tramadol, diazepam, Valium, zolpidem tartrate, clonazepam, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - August 16, 2019 Category: Medical Law Authors: DOJ Source Type: news
Too Few U.S. Opioid Users Are Getting OD Antidote
The new CDC report finds that too few doctors are prescribing naloxone as recommended to patients taking high-dose opioids or opioids plus benzodiazepines (such as Valium and Xanax), or to those with a substance use disorder. (Source: WebMD Health)
Source: WebMD Health - August 6, 2019 Category: Consumer Health News Source Type: news
Valium (diazepam) vs. Ambien (zolpidem)
Title: Valium (diazepam) vs. Ambien (zolpidem)Category: MedicationsCreated: 8/5/2019 12:00:00 AMLast Editorial Review: 8/5/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - August 5, 2019 Category: Drugs & Pharmacology Source Type: news
What Makes Consumers Satisfied?
Dear Dr. Jeff: Our facility administrator has asked all the “providers” to participate in a chain-wide program to boost “consumer satisfaction.” Our medical team would be happy to participate in quality improvement projects. But most of us object to the paradigm where our patients become consumers of medical care and we become short order cooks in a medical fast food chain, selling drugs on demand while wearing smile buttons. Good care often requires saying “no” to antipsychotics used as sleeping pills, excessive opioids, siderails, antibiotics for foul-smelling urine, Valium prescriptions for 90-year-olds, and...
Source: Caring for the Ages - July 30, 2019 Category: Health Management Authors: Jeffrey Nichols Tags: Dear Dr Jeff Source Type: news
The Rise of Intranasal Treatments in Epilepsy The Rise of Intranasal Treatments in Epilepsy
Dr Andrew Wilner speaks with Dr R. Edward Hogan about the rationale, evidence, and promise behind nasal formulations of diazepam and midazolam.Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - July 11, 2019 Category: Neurology Tags: Neurology & Neurosurgery Expert Interview Source Type: news
Valium (diazepam) vs. midazolam
Title: Valium (diazepam) vs. midazolamCategory: MedicationsCreated: 6/19/2019 12:00:00 AMLast Editorial Review: 6/19/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - June 19, 2019 Category: Drugs & Pharmacology Source Type: news
Cyclobenzaprine vs. Valium (diazepam)
Title: Cyclobenzaprine vs. Valium (diazepam)Category: MedicationsCreated: 6/6/2019 12:00:00 AMLast Editorial Review: 6/6/2019 12:00:00 AM (Source: MedicineNet Exercise and Fitness General)
Source: MedicineNet Exercise and Fitness General - June 6, 2019 Category: Podiatry Source Type: news
How Some Generic Drugs Could Do More Harm Than Good
For the 16 years that Dr. Brian Westerberg, a Canadian surgeon, worked volunteer missions at the Mulago National Referral Hospital in Kampala, Uganda, scarcity was the norm. The patients usually exceeded the 1,500 allotted beds. Running water was once cut off when the debt-ridden hospital was unable to pay its bills. On some of his early trips, Westerberg even brought over drugs from Canada in order to treat patients. But as low-cost generics made in India and China became widely available through Uganda’s government and international aid agencies in the early 2000s, it seemed at first like the supply issue had been ...
Source: TIME: Health - May 17, 2019 Category: Consumer Health News Authors: Katherine Eban Tags: Uncategorized generic drugs medication medicine Source Type: news
Doctors, Patients Struggle with Benzodiazepine Use
Along with Xanax, benzodiazepines include familiar brand names like the tranquilizer Valium (diazepam) and another anti-anxiety medication, Klonopin (clonazepam). (Source: WebMD Health)
Source: WebMD Health - May 16, 2019 Category: Consumer Health News Source Type: news
