How Some Generic Drugs Could Do More Harm Than Good

For the 16 years that Dr. Brian Westerberg, a Canadian surgeon, worked volunteer missions at the Mulago National Referral Hospital in Kampala, Uganda, scarcity was the norm. The patients usually exceeded the 1,500 allotted beds. Running water was once cut off when the debt-ridden hospital was unable to pay its bills. On some of his early trips, Westerberg even brought over drugs from Canada in order to treat patients. But as low-cost generics made in India and China became widely available through Uganda’s government and international aid agencies in the early 2000s, it seemed at first like the supply issue had been solved. Then on February 7, 2013, Westerberg examined a feverish 13-year-old boy who had fluid oozing from an ear infection. He suspected bacterial meningitis, though he couldn’t confirm his diagnosis because the CT scanner had broken down. The boy was given intravenous ceftriaxone, a broad-spectrum antibiotic that Westerberg believed would cure him. But after four days of treatment, the ear had only gotten worse. As Westerberg prepared to operate, the boy had a seizure. With the CT scanner working again, Westerberg ordered an urgent scan, which revealed small abscesses in the boy’s skull, likely caused by the infection. When a hospital neurosurgeon looked at the images and confidently declared that surgery was unnecessary and the swelling and abscesses would abate with effective antibiotic treatment, Westerberg was confused. They had already tr...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized generic drugs medication medicine Source Type: news

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Just went to a skills lab and they divided us into small groups. Before beginning each skills session, when asked what your primary specialty was, if the person teaching the skill was from an anesthesiology background, more times than not if you answered something other than anesthesia, the proctor would say something similar to "Well I guess you didn't get any training in this in residency". This included a session on suturing after procedures such as SCS or pumps. Not saying all those... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Conclusions Higher cardiovascular endurance may mitigate the relationship between poorer subjective sleep quality and lower EC thickness. Future longitudinal studies should examine the interactive effects of sleep and fitness on brain health among older and more vulnerable populations.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
Conclusions In conclusion, using contemporary methods to assess muscle architecture and calculate EFFPCSA did not enhance the muscle strength–size association. For understanding/monitoring muscle size, the major determinant of strength, these findings support the assessment of muscle volume, which is independent of architecture measurements and was most highly correlated with strength.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
AbstractKey messagesThe pathogenesis of subretinal neovascularization (SRNV) due to macular telengiectasia (MacTel 2) has not fully elucidated. This optical coherence tomography (OCT)-based method can provide better understanding of the pathogenesis of SRNV due to MacTel 2.PurposeTo evaluate the choroidal vascular index (CVI) through optical coherence tomography (OCT) on eyes with proliferative macular telangiectasia type 2 (MacTel 2) or non-proliferative MacTel 2, and in healthy individuals.MethodsMacular enhanced depth imaging OCT scans on 42 eyes of 21 patients with non-proliferative MacTel 2, on 32 eyes of 20 patients ...
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Ontario's proof-of-vaccination policy, set to take effect on Wednesday, treads into new territory for businesses. But Health Minister Christine Elliott has said she doesn't expect non-compliance to be an issue.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Toronto Source Type: news
September 19, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced a new analysis from the CHRYSALIS (NCT02609776) study evaluating RYBREVANT® (amivantamab-vmjw) monotherapy and a combination regimen with lazertinib in advanced non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations who progressed after osimertinib.[1] The analysis showed higher activity and longer duration of response (DOR) in patients treated with the combination therapy, demonstrating the potential benefit of targeting the extracellular (outer) and cataly...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Battling cancer is never easy but for Grande Prairie resident David Taylor, COVID-19 has delayed treatments, cancelled surgeries, allowed the disease to spread — and now it's stealing his last hope.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Edmonton Source Type: news
so i know the cdc published some data that you're 2.34x more likely to get covid from natural immunity than being vaccinated. Kentucky residents who were not vaccinated had 2.34 times the odds of reinfection compared with those who were fully vaccinated (odds ratio [OR] = 2.34; 95% confidence interval [CI] = 1.58–3.47). Not the greatest evidence to prove the point but hey i will believe that you have a higher chance of testing positive if youve previously had covid vs previous... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums
Exclusive: NHS launching large trial of approach that could boost number of transplants and their success rateThousands of lives could be saved globally by giving patients a 10p statin before transplants, doctors have said, as the NHS launches the world ’s largest clinical trial in organ donors.The medical breakthrough is predicted to dramatically increase the supply of organs for transplant. Currently, demand for organs vastly exceeds the number available. Every year thousands of people die waiting for a transplant, including hundreds in Britain.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Organ donation Statins Medical research NHS Health Society Science UK news Source Type: news
Well, maybe. In the KJV, the Philistines are afflicted with hemorrhoids. (Actually it uses the archaic word emorods, but that's what it means.) In verse 9, they specifically had emorods in their " secret parts. " Hey, it isn't funny -- Preparation H had yet to be invented.However, later translators have decided that the Hebrew word has a more general meaning, and most translate it as tumors. One hypothesis is that this is intended as a reference to bubonic plague. A footnote in the New International Version, which I'm giving here, says that the Septuagint has rats appearing in the land in verse 5, which would sup...
Source: Stayin' Alive - Category: American Health Source Type: blogs
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