New feline coronavirus blamed for thousands of cat deaths in Cyprus
When thousands of cats started to die this year on the Mediterranean island of Cyprus, nicknamed the “island of cats” for its 1-million-strong feline population, the crisis made international news. The animals had fevers, swollen bellies, and lethargy—symptoms that pointed to feline infectious peritonitis (FIP), a common condition caused by a type of cat coronavirus. But scientists struggled to explain the apparent explosion in cases. Now, researchers have identified a possible culprit: a new strain of feline coronavirus that has coopted key RNA sequences from a highly virulent dog pathogen cal...
Source: Science of Aging Knowledge Environment - November 14, 2023 Category: Geriatrics Source Type: research

Clinical research advances of CFHR5 nephropathy: a recent review
Eur Rev Med Pharmacol Sci. 2023 Oct;27(20):9987-10000. doi: 10.26355/eurrev_202310_34179.ABSTRACTCFHR5 nephropathy is a type of clinical C3 glomerulopathy, which is a monogenic genetic disease caused by the internal replication of CFHR5 gene, a protein related to the complement regulatory factor H family. The disease seems to be prevalent only in people of Greek Cypriot descent. Because of the special variation of the internal replication of exon 2 and exon 3 of CFHR5 protein in the occurrence of disease, it has had a serious impact on local residents. At present, the mechanism of glomerular damage caused by CFHR5 protein ...
Source: European Review for Medical and Pharmacological Sciences - November 2, 2023 Category: Drugs & Pharmacology Authors: Z-G Fei K Zhen F-J Zhang P-Y Liu H-Y Xu H-H Chen Source Type: research

Clinical research advances of CFHR5 nephropathy: a recent review
Eur Rev Med Pharmacol Sci. 2023 Oct;27(20):9987-10000. doi: 10.26355/eurrev_202310_34179.ABSTRACTCFHR5 nephropathy is a type of clinical C3 glomerulopathy, which is a monogenic genetic disease caused by the internal replication of CFHR5 gene, a protein related to the complement regulatory factor H family. The disease seems to be prevalent only in people of Greek Cypriot descent. Because of the special variation of the internal replication of exon 2 and exon 3 of CFHR5 protein in the occurrence of disease, it has had a serious impact on local residents. At present, the mechanism of glomerular damage caused by CFHR5 protein ...
Source: Pharmacological Reviews - November 2, 2023 Category: Drugs & Pharmacology Authors: Z-G Fei K Zhen F-J Zhang P-Y Liu H-Y Xu H-H Chen Source Type: research

Clinical research advances of CFHR5 nephropathy: a recent review
Eur Rev Med Pharmacol Sci. 2023 Oct;27(20):9987-10000. doi: 10.26355/eurrev_202310_34179.ABSTRACTCFHR5 nephropathy is a type of clinical C3 glomerulopathy, which is a monogenic genetic disease caused by the internal replication of CFHR5 gene, a protein related to the complement regulatory factor H family. The disease seems to be prevalent only in people of Greek Cypriot descent. Because of the special variation of the internal replication of exon 2 and exon 3 of CFHR5 protein in the occurrence of disease, it has had a serious impact on local residents. At present, the mechanism of glomerular damage caused by CFHR5 protein ...
Source: European Review for Medical and Pharmacological Sciences - November 2, 2023 Category: Drugs & Pharmacology Authors: Z-G Fei K Zhen F-J Zhang P-Y Liu H-Y Xu H-H Chen Source Type: research

A multicenter icet-a study on age at menarche and menstrual cycles in patients with transfusion-dependent thalassemia (tdt) who started early chelation therapy with different chelating agents.
Conclusions: Early chelation does not necessary correlate with efficient chelation during pubertal age. Delayed menarche, related to high SF levels, was still frequent in most Centers and was a forerunner of irregular menstrual cycles, SA and associated complications. Neglecting the importance of adherence to iron chelation therapy (ICT), despite innovative and expensive therapies, may lead to complications and decreased quality of life. Key words: Transfusion-dependent thalassemia, menarche, menstrual cycles, iron chelation therapy (ICT), iron overload, adherence to treatment.  (Source: Mediterranean Journal of ...
Source: Mediterranean Journal of Hematology and Infectious Diseases - October 30, 2023 Category: Hematology Authors: SALVATORE DI MAIO, VINCENZO DE SANCTIS, PIERLUIGI MARZUILLO, CHRISTOS KATTAMIS, SHAHINA DAAR, MEHERAN KARIMI, SAKI FOROUGH, ATANAS BANKEV, VALERIA KALEVA, SOTEROULA CHRISTOU, CARMELO FORTUGNO, POLYXENI DELAPORTA, ASHRAF T SOLIMAN , PLOUTARCHOS TZOULIS Source Type: research

Outcomes of Pain Management Among Postoperative Patients: A Cross-sectional Study
CONCLUSIONS: A holistic approach with evidence-based practices is crucial for adequate postoperative pain management. The recommendations include the development of individual pain outcome strategies to improve overall satisfaction with pain management among postoperative patients.PMID:37897477 | DOI:10.1016/j.jopan.2023.07.022 (Source: Journal of Perianesthesia Nursing)
Source: Journal of Perianesthesia Nursing - October 28, 2023 Category: Nursing Authors: Sandra Chirota Akire Nurhan Bayraktar Source Type: research