Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Cost of Cardiovascular Disease
Age-related disease places a huge financial burden on individuals and their caregivers; even the need for caregivers arises only because aging produces disability. Even only considering cardiovascular disease, the largest contribution to human mortality, the costs are enormous. This is a point often made by advocates arguing for greater institutional funding of ways to treat aging. Present levels of funding for research and development of means to reduce age-related disease are very low in comparison to the massive ongoing costs that result from age-related disease. It makes little sense for this to be the case in an age o...
Source: Fight Aging! - September 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Investigating Bacteria ’ s CRISPR Defense System to Improve Human Health
Credit: Adrian Sanchez Gonzales.
The earliest Andrew Santiago-Frangos, Ph.D., remembers being interested in science was when he was about 8 years old. He was home sick and became engrossed in a children’s book that explained how some bacteria and viruses cause illness. To this day, his curiosity about bacteria persists, and he’s making discoveries about CRISPR—a system that helps bacteria defend against viruses—as a postdoctoral researcher and NIGMS-funded Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) scholar at Montana State University (MSU) in Bozeman.
Becoming a Biologist...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 31, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Bacteria Cellular Processes COVID-19 DNA Profiles Source Type: blogs
Deltacron variant of COVID
The news is reporting this new variant (Guardian,Sky), which combines mutations from omicron and delta.PubMed today has only one item with that word, a piece from Nature, from February (so earlier than the news items) that has the title " the variant that wasn ' t " . A university in Cyprus had found the variant, but then reported that it was not a variant because their sample was contaminated.But, the Guardian and Sky pieces postdate the Nature item, and are reporting that the Institut Pasteur has sequenced the genome, and that the WHO news briefing of 9th March reported that there had been cases in the Nether...
Source: Browsing - March 12, 2022 Category: Databases & Libraries Tags: COVID-19 Source Type: blogs
Photographing the Physics of Cells
Dr. Melike Lakadamyali with a microscope. Credit: Courtesy of Dr. Lakadamyali.
“It would be a dream come true if I could look at a cell within a tissue and have a Google Maps view to zoom in until I saw individual molecules,” says Melike Lakadamyali, Ph.D., an associate professor of physiology at the University of Pennsylvania’s Perelman School of Medicine in Philadelphia. Her lab is helping make part of that dream a reality by developing super-resolution microscopy tools that visualize cells at a near-molecular level.
Blending Physics and Biology
Science and math fascinated Dr. Lakadamyali since childhood, ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 2, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Cellular Imaging Cellular Processes Cool Tools/Techniques Profiles Source Type: blogs
More Laughing, More Thinking
By KIM BELLARD
There was a lot going on this week, as there always is, including the 20th anniversary of 9/11 and the beginning of the NFL season, so you may have missed a big event: the announcement of the 31st First Annual Ig Nobel Awards (no, those are not typos).
What’s that you say — you don’t know the Ig Nobel Awards? These annual awards, organized by the magazine Annals of Improbable Research, seek to:
…honor achievements that make people LAUGH, then THINK. The prizes are intended to celebrate the unusual, honor the imaginative — and spur people’s interest in scie...
Source: The Health Care Blog - September 15, 2021 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Research health research Ignobel Kim Bellard Source Type: blogs
Sunday Sermonette: The definition of insanity . . .
. . . is doing the same thing repeatedly and expecting a different result. If you accept that, Balak evidently has that diagnosis. However, as I said before, the real reason for this story seems to be to provide a frame for presenting the songs, which come from a lost source. The only other comment I have at this point is to note again the oddity that the people are suddenly on the east side of the Jordan. They came from the west in Egypt, wandered around what was apparently the Sinai and the Negev (although the geography is generally quite vague) and now all of a sudden here they are on the east bank and the proposa...
Source: Stayin' Alive - October 4, 2020 Category: American Health Source Type: blogs
An Old NATO Nightmare Returns: Possible War between Greece and Turkey
Ted Galen CarpenterU.S. and other Western leaders have longworried about what to do if an armed conflict ever erupted between two NATO members.Rapidlyrising tensions between Greece and Turkey, primarily involving a maritime dispute over oil, natural gas, and other resources under the eastern Mediterranean, have brought that nightmare to the surface once again.Germany ’s Foreign Minister, Heiko Maas,warned both governments in late August against further military escalation. “Fire is being played with and any small spark could lead to catastrophe,” he stressed.The heart of the North Atlantic Treaty is Article 5, w...
Source: Cato-at-liberty - September 10, 2020 Category: American Health Authors: Ted Galen Carpenter Source Type: blogs
Managing Mutually Antagonistic Allies Is Like Herding Cats
One problem (among many) the United States has experienced in leading a vast array of allies and security dependents is that periodic quarrels break out among such clients. Even when the disputes are parochial and petty, the degree of animosity generated frequently is not. Not only does Washington then face the prospect of one or more of those allies breaking ranks and undermining U.S. policy objectives, but the danger exists that a confrontation might escalate to a cold war —or even a hot one.Deteriorating relations between two of Washington ’s prominent allies in East Asia–Japan and the Republic of Korea–are now ...
Source: Cato-at-liberty - August 8, 2019 Category: American Health Authors: Ted Galen Carpenter Source Type: blogs
Bitcoin After 10 Years
ConclusionBitcoin should not be regarded as the last word in private money, but should be appreciated as a remarkable technological breakthrough. Ten years after its launch, we must recognize it as the innovation that has launched financial and non-financial blockchain industries that are still in their early days. Bitcoin has established its value as an asset, and its usefulness as a medium of exchange for a certain subset of transactions. It is the main unit of account and payment medium, preferred to fiat monies, for markets in other cryptocurrencies below the top five. Whether it will achieve common use as a medium of ...
Source: Cato-at-liberty - October 23, 2018 Category: American Health Authors: Lawrence H. White Source Type: blogs
The Trump-Putin Summit: Opportunities and Pitfalls
Domestic and international politics surrounding the Trump administration ’s planned summit with Moscow are largely overshadowing the tangible U.S. national interests at play. Trump’s frequently expressed esteem for President Putin, along with his apparent admiration for authoritarian strongmen from Kim Jong Un to Rodrigo Duterte, rubs much of Washington and many U.S. allies, particularly in Europe, the wrong way for two reasons. First, it suggests that Trump is abandoning America’s purported role as a global defender of democracy. Second, it suggests that Trump is unwilling to take a tough stance toward Moscow despit...
Source: Cato-at-liberty - June 29, 2018 Category: American Health Authors: John Glaser, Ted Galen Carpenter Source Type: blogs
Profiles of Every Terrorism Vetting Failure in the Last 30 Years
In my newpolicy analysis released today, I identify 65 vetting failures where the visa vetting system allowed a foreign-born person to enter the United States as an adult or older teenager when they had already radicalized —80 percent occurred before 9/11. Just 13 vetting failures have occurred since 9/11, and only one—the last one (Tashfeen Malik)—resulted in any deaths in the United States. That’s one vetting failure for every 29 million visa or status approvals, and one deadly failure for every 379 million visa or status approvals from 2002 to 2016.As I note, 9/11 is reasonable point of analysis because after th...
Source: Cato-at-liberty - April 17, 2018 Category: American Health Authors: David Bier Source Type: blogs
Based on His Leaked 2005 Tax Data, Donald Trump Should Move to Italy (or the Isle of Man)
Themulti-faceted controversy over Donald Trump ’s taxes has been rejuvenated by a partial leak of his 2005 tax return.Interestingly, it appears that Trump pays a lot of tax. At least for that one year. Which is contrary to what a lot of people have suspected —including me inthe column I wrote on this topic last year forTime.Some Trump supporters are even highlighting the fact that Trump ’s effective tax rate that year was higher than what’s been paid by other political figures in more recent years.But I ’m not impressed. First, we have no idea what Trump’s tax rate was in other years. So the people defending Tr...
Source: Cato-at-liberty - March 15, 2017 Category: American Health Authors: Daniel J. Mitchell Source Type: blogs
Hypocrisy on Election Interference
In his press conference last month, President Barack Obama sternlyvoiced concern about “potential foreign influence in our election process.”The goal may be a valid one, but it cloaks hypocrisy of staggering proportions. The United States has been assiduously intervening in foreign elections for decades —perhaps even for centuries.The central issue in the 2016 election was with some hacked emails, published by Wikileaks, indicating that some top members of the Democratic National Committee were rooting for Hillary Clinton to win their party ’s nomination for president. This seems to have been the extent of the “i...
Source: Cato-at-liberty - January 4, 2017 Category: American Health Authors: John Mueller Source Type: blogs
Two Minimum Wage Charts for Andy Puzder
Donald Trump has tabbed Andy Puzder to lead the Department of Labor. Puzder is the CEO of CKE, the restaurant outfit (read: Hardee ’s and Carl’s Jr.). CKE, thanks to Puzder saving it from the bankruptcy hammer, employs 75,000 workers (read: jobs). Puzder knows that “high” minimum wages, such as the $15 per hour one thrown around by progressives, is a job killer for low-skill workers.During his nomination hearings, Andy Puzder will no doubt be grilled about his views on “high” minimum wages. His inquisitors will trot out glowing claims about the wonders of a $15 per hour minimum wage, as did President Obama in h...
Source: Cato-at-liberty - December 20, 2016 Category: American Health Authors: Steve H. Hanke Source Type: blogs
