Genes, Vol. 15, Pages 319: Massive Parallel DNA Sequencing of Patients with Inherited Cardiomyopathies in Cyprus and Suggestion of Digenic or Oligogenic Inheritance
We report on variants in 25 families, where pathogenicity was predicted by different computational approaches, databases, and an in-house filtering analysis. All variants were validated using Sanger sequencing. Familial segregation was tested when possible. We identified 41 different variants in 26 genes. Analytically, we identified fifteen variants previously reported in the Human Gene Mutation Database: twelve mentioned as disease-causing mutations (DM) and three as probable disease-causing mutations (DM?). Additionally, we identified 26 novel variants. We classified the forty-one variants as follows: twenty-eight (68.3%...
Source: Genes - February 28, 2024 Category: Genetics & Stem Cells Authors: Constantina Koutsofti Marios Ioannides Christiana Polydorou Gregory Papagregoriou Apostolos Malatras George Michael Irene Hadjiioannou Stylianos Pieri Eleni M. Loizidou Christos Eftychiou Elias Papasavvas Theodoros Christophides Anna Alkelai Manav Kapoor Tags: Article Source Type: research
Temporal patterns of cancer burden in Asia, 1990-2019: a systematic examination for the Global Burden of Disease 2019 study
This study examines the temporal patterns of incidence, mortality, disability and risk factors of 29 cancers in Asia in the last three decades.METHODS: The age, sex and year-wise estimates of incidence, mortality, and disability-adjusted life years (DALYs) of 29 cancers for 49 Asian countries from 1990 through 2019 were generated as a part of the Global Burden of Disease, Injuries and Risk Factors 2019 study. Besides incidence, mortality and DALYs, we also examined the cancer burden measured in terms of DALYs and deaths attributable to risk factors, which had evidence of causation with different cancers. The development st...
Source: Cancer Control - February 16, 2024 Category: Cancer & Oncology Authors: GBD 2019 Asia and All Cancers Collaborators Source Type: research
Promoting Linguistically Based Health Literacy in Doctors for Better Cancer Healthcare in Cyprus
AbstractThis paper explores a novel approach in cancer healthcare, underscoring the significance of fostering health literacy among doctors by enhancing their ability to employ linguistically oriented strategies to extract and interpret the linguistic behavior of patients. The focus is on the Greek-Cypriot context, where research on health literacy is still in its nascent stages. (Source: Journal of Cancer Education)
Source: Journal of Cancer Education - February 15, 2024 Category: Cancer & Oncology Source Type: research
Naturally occurring radioactive materials (NORM) concentration and health risk assessment of aerosols dust in Nicosia, North Cyprus
This study was carried out to evaluate the distribution of naturally occurring radioactive materials (NORM) and radiological risk indexes in aerosol dust in Nicosia, Cyprus utilizing a high-resolution HPGe gamma-spectrometry. The activity concentrations of226Ra,232Th, and40K in the selected aerosol dust samples ranged from 25.9 –52.4, 21.7–46.3, to 471–1302 Bq kg−1, respectively. The average activity concentrations of40K were found to be above the Earth's crust average. The internal and external hazard indexes are well below the acceptable limit in most dust samples. All investigated samples met the exemption dose...
Source: Journal of Radioanalytical and Nuclear Chemistry - February 6, 2024 Category: Nuclear Medicine Source Type: research
Epidemiology, risk factors, clinical presentation and complications of late-onset neonatal sepsis among preterm neonates in Cyprus: a prospective case-control study
Late-onset neonatal sepsis (LOS) is common in preterm neonates, with increasing incidence in recent years. In the present study, we examined the epidemiology, clinical presentation, and complications of LOS in... (Source: BMC Pediatrics)
Source: BMC Pediatrics - January 16, 2024 Category: Pediatrics Authors: Paraskevi Stylianou-Riga, Theodora Boutsikou, Panayiotis Kouis, Kyriaki Michailidou, Paraskevi Kinni, Rozeta Sokou, Zoi Iliodromiti, Constantinos Pitsios, Panayiotis K. Yiallouros and Nicoletta Iacovidou Tags: Research Source Type: research
Post-quarantine anxiety and depression levels of COVID-19 positive patients, Northern Cyprus
Conclusion: Although it was determined that the HAD scores of the individuals from NC infected with COVID-19 were not high, most of them needed psychological support as they stated in their own statements. (Source: African Health Sciences)
Source: African Health Sciences - December 27, 2023 Category: African Health Authors: Kaya Ufuk , G üvenir Meryem , Aykac Asli Source Type: research
Greek adaptation of the Teruel Orthorexia Scale (TOS) in adults from the Republic of Cyprus: A bidimensional model May not be universal
Appetite. 2023 Dec 23:107180. doi: 10.1016/j.appet.2023.107180. Online ahead of print.ABSTRACTThe Teruel Orthorexia Scale (TOS) is a 17-item instrument designed to assess distinct facets of Orthorexia Nervosa (ON) and Healthy Orthorexia (HO). While a bidimensional model of TOS scores has been supported in diverse national and linguistic groups, the psychometric properties of the TOS have not been previously assessed in Greek-speaking populations. To rectify this, we assessed the psychometric properties of a novel Greek translation of the TOS in a sample of adults from Cyprus. A total of 1248 respondents (710 women, 538 men...
Source: Appetite - December 25, 2023 Category: Nutrition Authors: Marios Argyrides Elly Anastasiades Christophe Ma ïano Viren Swami Source Type: research
Greek adaptation of the Teruel Orthorexia Scale (TOS) in adults from the Republic of Cyprus: A bidimensional model May not be universal
Appetite. 2023 Dec 23:107180. doi: 10.1016/j.appet.2023.107180. Online ahead of print.ABSTRACTThe Teruel Orthorexia Scale (TOS) is a 17-item instrument designed to assess distinct facets of Orthorexia Nervosa (ON) and Healthy Orthorexia (HO). While a bidimensional model of TOS scores has been supported in diverse national and linguistic groups, the psychometric properties of the TOS have not been previously assessed in Greek-speaking populations. To rectify this, we assessed the psychometric properties of a novel Greek translation of the TOS in a sample of adults from Cyprus. A total of 1248 respondents (710 women, 538 men...
Source: Appetite - December 25, 2023 Category: Nutrition Authors: Marios Argyrides Elly Anastasiades Christophe Ma ïano Viren Swami Source Type: research
In vivo challenge studies on vaccinated chickens indicate a virus genotype mismatched vaccine still offers significant protection against NDV
In conclusion, the ability of virulent APMV-1 to cause disease in vaccinated flocks is unlikely to be the result of antigenic mismatch alone, and other factors likely contribute to vaccination failure and breakthrough.PMID:38143198 | DOI:10.1016/j.vaccine.2023.12.037 (Source: Vaccine)
Source: Vaccine - December 24, 2023 Category: Allergy & Immunology Authors: Sahar Mahmood Paul Skinner Caroline J Warren Jo Mayers Joe James Alejandro N úñez Fabian Z X Lean Sharon M Brookes Ian H Brown Ashley C Banyard Craig S Ross Source Type: research
