Patient with 108-Degree Fever Shows Seriousness of Early Recognition & Treatment of Hyperthermia
Medic 35 is dispatched to a local subdivision for an obese 62-year-old woman with syncope. The responding unit is a fire-based ALS unit staffed by two paramedics. Patient Assessment It's approximately 2:30 p.m., with outside temperatures reaching 95 degrees F and the humidity is at 65%.The patient is lying in the grass next to a picnic blanket and paper plates with half eaten sandwiches. Her husband crouches over her. He says his wife started to complain she felt unwell, and then passed out. Upon evaluation, she's unresponsive to sternal rub. Her airway is patent. Her breaths are rapid and shallow with rales bilaterally. H...
Source: JEMS Patient Care - November 1, 2016 Category: Emergency Medicine Authors: Christine M. Brent, MD Tags: Patient Care Source Type: news

Cymbalta (Duloxetine Hcl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 22, 2016 Category: Drugs & Pharmacology Source Type: news

Accused murderer Richard Bain says he has no memory of election-night shooting
Richard Bain, dressed in a suit and tie, told the jury on Monday that he had no memory of the shooting at the Metropolis and that an anti-depressant called Cymbalta was making it difficult for him to tell the difference between right and wrong. (Source: CBC | Health)
Source: CBC | Health - July 18, 2016 Category: Consumer Health News Tags: News/Canada/Montreal Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl Methadon...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Depression blood test could lead to personalised treatments
Conclusion This study shows how a new blood test in development can help identify people with depression who are most and least likely to benefit from antidepressants. While promising, the test is far from perfect. For example, it missed 39-43% of non-responders, meaning these people would continue to receive standard antidepressant treatment that is unlikely to work for them. A large proportion of patients (22-38%) also fell into the "intermediate" group who were neither responders nor non-responders, so the test wasn't too useful here. This means there is a significant proportion of people with depression ...
Source: NHS News Feed - June 7, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news

Antidepressants linked to suicide and aggression in teens
ConclusionPerhaps the most troubling aspect of this paper is not the increased risk of suicidal thoughts in young people, as that has been known for many years. What is worrying is the researchers’ conclusion that they are unable to tell the true extent of harms from antidepressants, because of poor data collection and availability.RCTs are designed to test the effects of treatments with as little bias as possible. However, if the right data on adverse effects is not collected in the trials, or is not made public, we cannot balance the benefits and risks of treatment in a fair and transparent way. According to the data w...
Source: NHS News Feed - January 28, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news

Depression medication could help knee osteoarthritis
Researchers at our pain centre are recruiting people to take part in a clinical trial to determine whether duloxetine, a drug normally used to help people with anxiety or depression, can also be effective against the pain of knee osteoarthritis. Current treatments for tackling osteoarthritis are limited. If results from the trial are positive, it could provide a new treatment option for millions of people living with chronic knee pain. Diane Reckziegel, from The University of Nottingham and chief investigator for the study, said: “Duloxetine has already been shown to be effective in relieving different types of chronic p...
Source: Arthritis Research UK - December 23, 2015 Category: Rheumatology Source Type: news

Make the Diagnosis: Senior's Skin Affliction
(MedPage Today) -- Case Findings: A 60-year-old woman presents and describes a history of intermittent episodes of fluid-filled blisters on her abdomen, back, and arms. When the blisters ruptured, they caused moist erosions that led to post-inflammatory hyperpigmentation in the form of pink lesions. She had been taking Cymbalta, and the condition persisted when she discontinued the medication. What is your diagnosis? (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - November 24, 2015 Category: Dermatology Source Type: news

Living with Panic Attacks
You’re sitting in your car trying to will yourself to walk into the grocery store. Anxiety washes over you. You’re cold and hot at the same time with sweat trickling down your back, hair standing on your arms. You finally get out of your car. But as you enter the store, you feel wobbly and like you’re going to pass out. The fluorescent lighting seems especially stifling. The wide aisles, oddly enough, feel claustrophobic. Your breath feels finite, like a balloon floating up to the sky, which you can’t catch. In fact, at times you feel like you’re floating along with the balloon. At times you feel like Edvard Munc...
Source: Psych Central - September 3, 2015 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Anxiety Cognitive-Behavioral Disorders General Psychotherapy Relaxation and Meditation Self-Esteem Self-Help Stress Academy of Cognitive Therapy Agoraphobia Antidepressant Anxiety Disorder Association for Behavioral and Cognitive Source Type: news

Lupin launches 40 mg Duloxetine DR capsules in the US
Lupin is now the only generic manufacturer to offer all Duloxetine dosage strengths - the 20 mg, 30 mg, 60 mg, and now the newest 40 mg. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 3, 2015 Category: Pharmaceuticals Source Type: news

U.S. jury clears Eli Lilly in first Cymbalta withdrawal trial
(Reuters) - Eli Lilly on Friday was cleared of liability in the first trial involving claims that its antidepressant Cymbalta caused severe withdrawal symptoms, including suicidal thoughts and electric shock-like sensations, the company said. (Source: Reuters: Health)
Source: Reuters: Health - August 8, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Eli Lilly faces first U.S. trials over Cymbalta withdrawal
NEW YORK (Reuters) - Eli Lilly & Co on Tuesday will confront the first U.S. trial over allegations it failed to warn users of its popular antidepressant Cymbalta that they could suffer severe withdrawal symptoms, including suicidal thoughts and electric shock-like sensations. (Source: Reuters: Health)
Source: Reuters: Health - August 3, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

CHMP Backs Three Generics for Major Mental IllnessesCHMP Backs Three Generics for Major Mental Illnesses
The EMA committee gives green light to Duloxetine Zentiva, Aripiprazole Sandoz, and Pregabalin Accord. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - June 26, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

Lilly Heads to Court Over Cymbalta "Brain Zap" Withdrawal Issues
Eli Lilly will face jury trials in August for claims it misled consumers about withdrawal side effects tied to its antidepressant Cymbalta. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - June 25, 2015 Category: Pharmaceuticals Source Type: news

Medication and Anxiety
Medication can be an effective approach for managing various types of anxiety such as panic, hyperarousal, and constant worry. However, contrary to popular belief and subtle messages from pharmaceutical companies, medication is far from a cure. In fact, when it comes to “cures” for most psychiatric conditions, the data tends to support psychotherapy. For example, post-traumatic stress disorder (PTSD) responds very well to psychotherapy, whereas the positive effects of medication are somewhat limited. The same is true for panic disorder. Although certain types of medication are very good at relieving panic sympt...
Source: Psych Central - March 11, 2015 Category: Psychiatry Authors: Bret Moore, PsyD Tags: Anti-anxiety Antidepressants Benzodiazepines Disorders General Medications Panic Disorder anti-anxiety medications Drug Dependency Fear Hyperarousal Sedatives Selective Serotonin Reuptake Inhibitor snri Ssri Substance Abuse Source Type: news