Improving Evidence-Based Practice through Preregistration of Applied Research: Barriers and Recommendations
Account Res. 2021 Aug 16. doi: 10.1080/08989621.2021.1969233. Online ahead of print.ABSTRACTPreregistration is the practice of publicly publishing plans on central components of the research process before access to, or collection, of data. Within the context of the replication crisis, open science practices like preregistration have been pivotal in facilitating greater transparency in research. However, such practices have been applied nearly exclusively to basic academic research, with rare consideration of the relevance to applied and consultancy-based research. This is particularly problematic as such research is typic...
Source: Accountability in Research - August 16, 2021 Category: Medical Ethics Authors: Thomas Rhys Evans Peter Branney Andrew Clements Ella Hatton Source Type: research
Improving Evidence-Based Practice through Preregistration of Applied Research: Barriers and Recommendations
Account Res. 2021 Aug 16. doi: 10.1080/08989621.2021.1969233. Online ahead of print.ABSTRACTPreregistration is the practice of publicly publishing plans on central components of the research process before access to, or collection, of data. Within the context of the replication crisis, open science practices like preregistration have been pivotal in facilitating greater transparency in research. However, such practices have been applied nearly exclusively to basic academic research, with rare consideration of the relevance to applied and consultancy-based research. This is particularly problematic as such research is typic...
Source: Accountability in Research - August 16, 2021 Category: Medical Ethics Authors: Thomas Rhys Evans Peter Branney Andrew Clements Ella Hatton Source Type: research
Improving Evidence-Based Practice through Preregistration of Applied Research: Barriers and Recommendations
Account Res. 2021 Aug 16. doi: 10.1080/08989621.2021.1969233. Online ahead of print.ABSTRACTPreregistration is the practice of publicly publishing plans on central components of the research process before access to, or collection, of data. Within the context of the replication crisis, open science practices like preregistration have been pivotal in facilitating greater transparency in research. However, such practices have been applied nearly exclusively to basic academic research, with rare consideration of the relevance to applied and consultancy-based research. This is particularly problematic as such research is typic...
Source: Accountability in Research - August 16, 2021 Category: Medical Ethics Authors: Thomas Rhys Evans Peter Branney Andrew Clements Ella Hatton Source Type: research
What We Learned in 25 Years of Interactive Molecular Design Sessions
ChemMedChem. 2021 Aug 10. doi: 10.1002/cmdc.202100351. Online ahead of print.ABSTRACTWe retrace Prof. François Diederich's consultancy work for Roche and its impact over the years he worked with us. François Diederich uniquely shaped our approach to molecular design, and interactions with him and his research group at ETH Zurich have created deep insights into molecular recognition. Herein we share how his style and approach continue to inspire us.PMID:34374230 | DOI:10.1002/cmdc.202100351 (Source: ChemMedChem)
Source: ChemMedChem - August 10, 2021 Category: Chemistry Authors: Bernd Kuhn Wolfgang Haap Ulrike Obst-Sander Christian Kramer Martin Stahl Source Type: research
What We Learned in 25 Years of Interactive Molecular Design Sessions
ChemMedChem. 2021 Aug 10. doi: 10.1002/cmdc.202100351. Online ahead of print.ABSTRACTWe retrace Prof. François Diederich's consultancy work for Roche and its impact over the years he worked with us. François Diederich uniquely shaped our approach to molecular design, and interactions with him and his research group at ETH Zurich have created deep insights into molecular recognition. Herein we share how his style and approach continue to inspire us.PMID:34374230 | DOI:10.1002/cmdc.202100351 (Source: ChemMedChem)
Source: ChemMedChem - August 10, 2021 Category: Chemistry Authors: Bernd Kuhn Wolfgang Haap Ulrike Obst-Sander Christian Kramer Martin Stahl Source Type: research
The Views of People Who Experienced the Reduction of the Concerns in the COVID-19 Quarantine Process by Making Physical Activity at Home
This study aims to investigate how COVID-19 affects the social life and the anxiety levels of people at home during the quarantine process within the framework of a solution-oriented approach. In this study, one of the qualitative research patterns "phenomenology" has been used to determine the opinions of the participants. The study group of the research consists of 14 people with moderate income who actively participate in anxiety-reducing activities of an International Coach Federation (ICF) consultancy center in İstanbul. The themes have been created in line with the answers obtained by the result of content analysis ...
Source: Social Work in Public Health - July 5, 2021 Category: International Medicine & Public Health Authors: Özge Ercan Source Type: research
Does social support affect menopausal symptoms in menopausal women?
AbstractPurposeTo determine the effect of perceived social support of menopausal women on their menopausal complaints.Design and MethodsThis descriptive and correlational study was conducted with 505 women. The data were obtained using personal information form, menopause rating scale, and multidimensional scale of perceived social support. Frequency, percentage,t test, analysis of variance Skewness and Kurtosis ( ±1) and correlation were used in the analysis of the data.FindingsIn the study, it was found that there was a positive and significant relationship between menopausal symptoms and social support, and menopausal ...
Source: Perspectives in Psychiatric Care - July 2, 2021 Category: Psychiatry Authors: Filiz Polat,
Ilksen Orhan,
Didem Şimşek Küçükkelepçe Tags: ORIGINAL ARTICLE Source Type: research
A prospective cohort study of ambient air pollution exposure and risk of uterine leiomyomata
AbstractSTUDY QUESTIONTo what extent are ambient concentrations of particulate matter<2.5 microns (PM2.5), nitrogen dioxide (NO2) and ozone (O3) associated with risk of self-reported physician-diagnosed uterine leiomyomata (UL)?SUMMARY ANSWERIn this large prospective cohort study of Black women, ambient concentrations of O3, but not PM2.5 or NO2, were associated with increased risk of UL.WHAT IS KNOWN ALREADYUL are benign tumors of the myometrium that are the leading cause of gynecologic inpatient care among reproductive-aged women. Black women are clinically diagnosed at two to three times the rate of white women and t...
Source: Human Reproduction - May 13, 2021 Category: Reproduction Medicine Source Type: research
The effect of polymorphisms in FSHR and FSHB genes on ovarian response: a prospective multicenter multinational study in Europe and Asia
This study was supported by an unrestricted grant by Merck Sharp& Dohme (MSD). N.P.P. reports grants and/or personal fees from MSD, Merck Serono, Roche Diagnostics, Ferring International, Besins Healthcare, Gedeon Richter, Theramex, and Institut Biochimique SA (IBSA). N.L.V. and M.T.H. report consultancy and conference fees from Merck, Ferring, and MSD, outside the submitted work. P.D. has received honoraria for lecturing and/or research grants from MSD, Ferring International, and Merck. D.S. reports grants and/or personal fees from MSD, Ferring International, Merck Serono, Cook, and Gedeon Richter. A.R.N., B.A.M., C.S...
Source: Human Reproduction - April 23, 2021 Category: Reproduction Medicine Source Type: research
Effect of parental and ART treatment characteristics on perinatal outcomes
This study was funded by Foreest Medical School, Alkmaar, the Netherlands (grants: FIO 1307 and FIO 1505). B.W.M. reports grants from NHMRC and consultancy for ObsEva, Merck KGaA, iGenomics and Guerbet. F.B. reports research support grants from Merck Serono and personal fees from Merck Serono. A.C. reports travel support from Ferring BV. and Theramex BV. and personal fees from UpToDate (Hyperthecosis), all outside the remit of the current work. The remaining authors report no conflict of interests.TRIAL REGISTRATION NUMBERN/A. (Source: Human Reproduction)
Source: Human Reproduction - April 16, 2021 Category: Reproduction Medicine Source Type: research
Worker Well-Being: What it Is, and how it Should Be Measured
AbstractWorker well-being is a hot topic in organizations, consultancy and academia. However, too often, the buzz about worker well-being, enthusiasm for new programs to promote it and interest to research it, have not been accompanied by universal enthusiasm for scientific measurement. Aim to bridge this gap, we address three questions. To address the question ‘What is worker well-being?’, we explain that worker well-being is a multi-facetted concept and that it can be operationalized in a variety of constructs. We propose a four-dimensional taxonomy of worker well-being constructs to illustrate the concept’s comple...
Source: Applied Research in Quality of Life - March 26, 2021 Category: International Medicine & Public Health Source Type: research
Patient willingness, preferences and decision-making about planning for three complete cycles of IVF/ICSI treatment
AbstractSTUDY QUESTIONWhat is willingness, preference and decision-making about planning for the possibility of needing multiple cycles of IVF/ICSI treatment among patients consulting for a first or repeat stimulated IVF/ICSI cycle?SUMMARY ANSWERThe majority of patients seem to value the opportunity to plan for multiple cycles of treatment while acknowledging both possible challenges and benefits of doing so and decisions that might need to be made in advance.WHAT IS KNOWN ALREADYPatients have strong intentions to do treatment to achieve pregnancy and approximately 48 –54% continue treatment when confronted with a failed...
Source: Human Reproduction - March 21, 2021 Category: Reproduction Medicine Source Type: research
Cost-effectiveness of ovarian stimulation agents for IUI in couples with unexplained subfertility
AbstractSTUDY QUESTIONWhich agent for ovarian stimulation (OS) is the most cost-effective option in terms of net benefit for couples with unexplained subfertility undergoing IUI?SUMMARY ANSWERIn settings where a live birth is valued at €3000 or less, between €3000 and €55 000 and above €55 000, clomiphene citrate (CC), Letrozole and gonadotrophins were the most cost-effective option in terms of net benefit, respectively.WHAT IS KNOWN ALREADYIUI-OS is a common first-line treatment for couples with unexplained subfertility and its increased uptake over the past decades and related personal or reimbursed costs are pre...
Source: Human Reproduction - February 22, 2021 Category: Reproduction Medicine Source Type: research
Food and Sustainability in the Twenty-First Century
Sustainability is one of the great problems facing food production today...this volume brings many new perspectives to the problems we face. Its cross-disciplinary framework of chapters with local, regional and continental perspectives provides a global outlook on sustainability issues. These case studies will appeal to those working in public sector agencies, NGOs, consultancies and other bodies focused on food security, human nutrition and environmental sustainability. —Publishers (Source: Journal of Nutrition Education and Behavior)
Source: Journal of Nutrition Education and Behavior - February 1, 2021 Category: Nutrition Authors: Bret Luick Tags: New Resources for Nutrition Educators Source Type: research
