Assessment of remifentanil for rapid sequence induction and intubation in patients at risk of pulmonary aspiration of gastric contents compared to rapid-onset paralytic agents: study protocol for a non-inferiority simple blind randomized controlled trial (the REMICRUSH study)
DiscussionThe REMICRUSH trial protocol has been approved by the ethics committee of The Comit é de Protection des Personnes Sud-Ouest et Outre-Mer II and will be carried out according to the principles of the Declaration of Helsinki and the Good Clinical Practice guidelines. The results of this study will be disseminated through presentations at scientific conferences and publications in pe er-reviewed journals. The REMICRUSH trial is the first randomized controlled trial powered to investigate whether remifentanil with hypnotics is non-inferior to rapid-onset paralytic agents with hypnotic in rapid sequence induction of ...
Source: Trials - March 30, 2021 Category: Research Source Type: clinical trials
Lilly's Donanemab Slowed Alzheimer's Disease Progression in Phase 2 Trial: Full Data Presented at AD/PD ™ 2021 and Published in NEJM
INDIANAPOLIS, March 13, 2021 /PRNewswire/ -- Phase 2 TRAILBLAZER-ALZ results presented today by Eli Lilly and Company (NYSE: LLY) at the 15th International Conference on Alzheimer ' s& Parkinson Diseases™ 2021 (AD/PD™ 2021)... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 13, 2021 Category: Pharmaceuticals Source Type: clinical trials
The VESPA Pilot Study
Conditions: Exercise; Behavior; Loneliness; Social Isolation Interventions: Behavioral: Virtual Reality; Behavioral: Video Conference Sponsors: Wake Forest University; Wells Fargo Faculty Scholar Endowment Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 16, 2021 Category: Research Source Type: clinical trials
COHESION: core outcomes in neonatal encephalopathy (protocol)
This study is registered in the Core Outcome Measures for Effectiveness (COMET) databasehttp://www.comet-initiative.org/Studies/Details/1270. (Source: Trials)
Source: Trials - February 8, 2021 Category: Research Source Type: clinical trials
Core outcomes set for research on the treatment of opioid use disorder (COS-OUD): the National Institute on Drug Abuse Clinical Trials Network protocol for an e-Delphi consensus study
DiscussionThis initiative will develop a COS for OUD intervention trials, treatment studies, and service delivery and will support the pooling of research and clinical practice data and efforts to develop measurement-based care within the OUD treatment cascade.Trial registrationhttp://www.comet-initiative.org/Studies/Details/1579 (Source: Trials)
Source: Trials - January 28, 2021 Category: Research Source Type: clinical trials
Strategy for addressing research-site overlap in pragmatic clinical trials: lessons learned from the NIH-DOD-VA Pain Management Collaboratory (PMC)
ConclusionProactive strategies can be used to resolve the issue of overlapping research sites in the PMC. These strategies, combined with open and impartial mediation approaches that include researchers, sponsors, and stakeholders, provide lessons learned from this large and complex pragmatic research effort. (Source: Trials)
Source: Trials - December 11, 2020 Category: Research Source Type: clinical trials
Acurx Announces Positive Phase 2A Clinical Trial Results for Ibezapolstat in C. difficile Infection at Prominent International Conference
WHITE PLAINS, N.Y., Nov. 19, 2020 /PRNewswire/ -- Acurx Pharmaceuticals, LLC ( " Acurx " or the " Company " ), a privately held, clinical stage biopharmaceutical company developing a new class of antibiotics for difficult-to-treat bacterial... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 19, 2020 Category: Pharmaceuticals Source Type: clinical trials
