Caries inhibition with CO2-laser during orthodontic treatment: a study protocol for a randomized split-mouth controlled clinical trial
AbstractIntroductionWhite spot lesions associated with orthodontic treatment are a common problem. Recent studies reported increased resistance to acid demineralization of enamel after sub-ablative CO2-laser irradiation in a combination with fluoride application. The aim of the study is to assess the efficacy of CO2-laser in combination with a fluoride varnish in the prevention, severity, and extent of white spot lesions during orthodontic treatment with fixed appliances.Methods and analysisThis is a protocol for a randomized, split-mouth controlled, clinical trial. The participants will be children aged 12 –18 years a...
Source: Trials - March 12, 2022 Category: Research Source Type: clinical trials
Specialist Conferences Between General Practitioners and Endocrinologists
Condition: Diabetes Mellitus, Type 2 Intervention: Other: Virtual specialist conferences Sponsors: University of Aarhus; Aarhus University Hospital; Region MidtJylland Denmark Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2022 Category: Research Source Type: clinical trials
Implementation of an in situ simulation-based training adapted from Morbidity and Mortality conference cases: effect on the occurrence of adverse events —study protocol of a cluster randomised controlled trial
DiscussionThe in situ simulation training based on cases processed in Morbidity and Mortality conference is built according to the main topics identified for the successful implementation of healthcare simulation in patient safety programmes: technical skills, nontechnical skills, assessment, effectiveness, and system probing. The in situ simulation-training programme conducted as part of the study has the potential to improve patient safety during hospitalisation. We therefore expect the greatest reduction in the occurrence of adverse events in patients hospitalised in the active feedback arm. This expected result would h...
Source: Trials - February 2, 2022 Category: Research Source Type: clinical trials
Effects of Bushen-Jiangya granules on blood pressure and pharmacogenomic evaluation in low-to-medium-risk hypertensive patients: study protocol for a randomized double-blind controlled trial
This study has been approved by the Research Ethics Committee of Guang ’anmen Hospital, China Academy of Chinese Medical Sciences in Beijing, China (No. 2019-186-KY-01). The participants are volunteers, understand the process of this trial, and sign an informed consent. The results of this study will be disseminated to the public through peer-reviewed journals and ac ademic conferences.DiscussionWe hypothesize that patients with low-to-medium-risk hypertension will benefit from BSJY. If successful, this study will provide evidence-based recommendations for clinicians.Trial registrationChinese Clinical Trial Registry ChiM...
Source: Trials - January 15, 2022 Category: Research Source Type: clinical trials
Efficacy of Chinese herbal medicine Jiangniaosuan formula for treatment of hyperuricemia: study protocol for a double-blinded non-inferiority randomized controlled clinical trial
This study will provide evidence-based recommendations for clinicians.DisseminationThe results will be published in a peer-reviewed journal and disseminated by academic conferences. The datasets analyzed during the current study are available from the corresponding author on reasonable request.Trial registrationChinese Clinical Trials RegisterChiCTR2000041083. Registered on 3 May 2021. The protocol version number is V3.0, 20210301. (Source: Trials)
Source: Trials - January 3, 2022 Category: Research Source Type: clinical trials
Effectiveness and safety of Bushen Huoxue granules in treatment of premature ovarian insufficiency: study protocol for a randomized, double-blinded, placebo-controlled, and multicenter clinical trial
This study was approved by the Research Ethics Committee of Jiangsu Province Hospital on Integration of Chinese and Western Medicine (2019LWKY014). All participants will provide written informed consent prior to randomization. The results of this research will be presented to academic conferences and peer-reviewed journals.Trial registrationChiCTR1900028451. Registered on 22 December 2019,https://www.chictr.org.cn/index.aspx. (Source: Trials)
Source: Trials - December 4, 2021 Category: Research Source Type: clinical trials
