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Expression of Concern: Sunlit expeditious visible light-mediated photo-Fenton degradation of Ciprofloxacin by exfoliation of NiCo(2)O(4) and Zn(0.3)Fe(2.7)O(4) over g-C(3)N(4) matrix: A brief insight on degradation mechanism, degraded product toxicity, and genotoxic evaluation in Allium cepa (Chemosphere, Volume 303, Part 1, September 2022, 134963)
Chemosphere. 2024 Apr;353:141612. doi: 10.1016/j.chemosphere.2024.141612. Epub 2024 Mar 2.NO ABSTRACTPMID:38528405 | DOI:10.1016/j.chemosphere.2024.141612 (Source: Chemosphere)
Source: Chemosphere - March 26, 2024 Category: Chemistry Source Type: research

SOS genes are rapidly induced while translesion synthesis polymerase activity is temporally regulated
The DNA damage inducible SOS response in bacteria serves to increase survival of the species at the cost of mutagenesis. The SOS response first initiates error-free repair followed by error-prone repair. Here, we have employed a multi-omics approach to elucidate the temporal coordination of the SOS response. Escherichia coli was grown in batch cultivation in bioreactors to ensure highly controlled conditions, and a low dose of the antibiotic ciprofloxacin was used to activate the SOS response while avoiding extensive cell death. Our results show that expression of genes involved in error-free and error-prone repair were bo...
Source: Frontiers in Microbiology - March 26, 2024 Category: Microbiology Source Type: research

Sensors, Vol. 24, Pages 2126: Efficient Sequential Detection of Two Antibiotics Using a Fiber-Optic Surface Plasmon Resonance Sensor
Huang Su Antibiotic residues have become a worldwide public safety issue. It is vital to detect multiple antibiotics simultaneously using sensors. A new and efficient method is proposed for the combined detection of two antibiotics (enrofloxacin (Enro) and ciprofloxacin (Cip)) in milk using surface plasmon resonance (SPR) sensors. Based on the principle of immunosuppression, two antibiotic antigens (for Enro and Cip) were immobilized on an optical fiber surface with conjugates of bovine serum albumin using dopamine (DA) polymerization. Each single antigen was bound to its corresponding antibody to derive standard c...
Source: Sensors - March 26, 2024 Category: Biotechnology Authors: Zhao Yin Xiao Cui Huang Su Tags: Article Source Type: research

Chemically synthesized ciprofloxacin-PEG-FeO nanotherapeutic exhibits strong antibacterial and controlled cytotoxic effects
Nanomedicine, Ahead of Print. (Source: Future Medicine: Nanomedicine)
Source: Future Medicine: Nanomedicine - March 26, 2024 Category: Nanotechnology Authors: Hussan Sobia Nisa Syeda Asma Bano Muhammad Zia Source Type: research

Chemically synthesized ciprofloxacin-PEG-FeO nanotherapeutic exhibits strong antibacterial and controlled cytotoxic effects
Nanomedicine, Ahead of Print. (Source: Nanomedicine)
Source: Nanomedicine - March 26, 2024 Category: Nanotechnology Authors: Hussan Sobia Nisa Syeda Asma Bano Muhammad Zia Source Type: research

Quorum-sensing regulation of phenazine production heightens < em > Pseudomonas aeruginosa < /em > resistance to ciprofloxacin
This study illustrates the role of quorum sensing-mediated phenotypic resistance and suggests a strategy for its prevention.PMID:38526048 | DOI:10.1128/aac.00118-24 (Source: Antimicrobial Agents and Chemotherapy)
Source: Antimicrobial Agents and Chemotherapy - March 25, 2024 Category: Microbiology Authors: Lexin Xia Yue Li Yufan Wang Hui Zhou Ajai A Dandekar Feng Xu Meizhen Wang Source Type: research

Stenotrophomonas maltophilia neonatal sepsis: a case report
ConclusionsThis report describes a neonatal sepsis case caused byS. maltophilia, a multi-drug resistant bacteria and a rare cause of neonatal sepsis. We report that early detection of the bacterial and antimicrobial management based on local antibiogram data may be essential for successful patient ’s management. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 25, 2024 Category: General Medicine Source Type: research

Mechanistic study of the electrochemical oxidation of fluoroquinolones: Ciprofloxacin, danofloxacin, enoxacin, levofloxacin and lomefloxacin
Chemosphere. 2024 Mar 22:141763. doi: 10.1016/j.chemosphere.2024.141763. Online ahead of print.ABSTRACTThe fluoroquinolones ciprofloxacin, danofloxacin, enoxacin, levofloxacin and lomefloxacin, occur in water bodies worldwide and therefore pose a threat to the aquatic environment. Advanced purification procedures, such as electrochemical oxidation, may act as a remedy since they contribute to eliminating contaminants and prevent micropollutants from entering open water bodies. By electrochemical treatment in a micro-flow reactor equipped with a boron-doped diamond (BDD) electrode, the fluoroquinolones were efficiently degr...
Source: Chemosphere - March 24, 2024 Category: Chemistry Authors: Melanie Voigt Jean-Michel Dluziak Nils Wellen Martin Jaeger Source Type: research

2,3-Dichloronaphthoquinone derivatives: Synthesis, antimicrobial activity, molecular modelling and ADMET studies
Bioorg Chem. 2024 Mar 20;146:107300. doi: 10.1016/j.bioorg.2024.107300. Online ahead of print.ABSTRACTIn the present study, an intermediate namely 2-(3-bromopropylamino)-3-chloronaphthalene-1,4-dione was initially synthesized via the nucleophilic addition-elimination reaction between 2,3-dichloro-1,4-naphthoquinone and 3-bromo-1-aminopropane. Then a coupling reaction between the intermediate and piperazine derivatives yielded a number of 1,4-naphthoquinone derivatives. Spectroscopic analysis successfully characterized the products that were obtained in good yields. In vitro antibacterial properties of the compounds were ex...
Source: Bioorganic Chemistry - March 24, 2024 Category: Chemistry Authors: Hakan Kolanc ılar Hafize Özcan Ay şen Şuekinci Yılmaz Alparslan Semih Salan Abdulilah Ece Source Type: research