Risk of fetal loss after chorionic villus sampling in twin pregnancies derived from propensity score matching analysis
CONCLUSIONS: After accounting for the risk factors that lead to both CVS and spontaneous fetal loss and confining the analysis to pregnancies at lower prior risk, CVS seems to increase the risk of fetal loss by about 3.5% above the patient's background-risk. This article is protected by copyright. All rights reserved.PMID:34845786 | DOI:10.1002/uog.24826 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - November 30, 2021 Category: Radiology Authors: M M Gil M Rodr íguez-Fernández T Elger R Akolekar A Syngelaki C De Paco Matallana F S Molina M Gallardo Arozena P Chaveeva N Persico V Accurti K O Kagan N Prodan J Cruz K H Nicolaides Source Type: research

Risk of fetal loss after chorionic villus sampling in twin pregnancies derived from propensity score matching analysis
CONCLUSIONS: After accounting for the risk factors that lead to both CVS and spontaneous fetal loss and confining the analysis to pregnancies at lower prior risk, CVS seems to increase the risk of fetal loss by about 3.5% above the patient's background-risk. This article is protected by copyright. All rights reserved.PMID:34845786 | DOI:10.1002/uog.24826 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - November 30, 2021 Category: Radiology Authors: M M Gil M Rodr íguez-Fernández T Elger R Akolekar A Syngelaki C De Paco Matallana F S Molina M Gallardo Arozena P Chaveeva N Persico V Accurti K O Kagan N Prodan J Cruz K H Nicolaides Source Type: research

Angiogenic factors measured in aspirated placental tissue between the 10  + 6 and 18 + 3 weeks of gestation
This study was designed to determine the level of vascular endothelial growth factor-A (VEGF-A), basic fibroblast growth factor (bFGF) and endothelial nitric oxide synthase (eNOS) in chorionic villi during in first and second trimester, and their association with nuchal translucency (NT) measured by ultrasound. Seventy-five singleton healthy pregnancies with no detected congenital malformation were collected for NT measurements and chorionic villus sampling (CVS). Concentrations of angiogenic factors were assayed in chorionic villi sampled between 10 + 6 and 18 + 3 weeks of gestation. ENOS level was steady during this gest...
Source: Reproductive Biology - November 19, 2021 Category: Reproduction Medicine Authors: J ános Sikovanyecz M árió Vincze Imre F öldesi G ábor Németh Zoltan Kozinszky Source Type: research

Angiogenic factors measured in aspirated placental tissue between the 10  + 6 and 18 + 3 weeks of gestation
This study was designed to determine the level of vascular endothelial growth factor-A (VEGF-A), basic fibroblast growth factor (bFGF) and endothelial nitric oxide synthase (eNOS) in chorionic villi during in first and second trimester, and their association with nuchal translucency (NT) measured by ultrasound. Seventy-five singleton healthy pregnancies with no detected congenital malformation were collected for NT measurements and chorionic villus sampling (CVS). Concentrations of angiogenic factors were assayed in chorionic villi sampled between 10 + 6 and 18 + 3 weeks of gestation. ENOS level was steady during this gest...
Source: Reproductive Biology - November 19, 2021 Category: Reproduction Medicine Authors: J ános Sikovanyecz M árió Vincze Imre F öldesi G ábor Németh Zoltan Kozinszky Source Type: research

Consensus on Training and Assessment of Competence in Performing Chorionic Villus Sampling and Amniocentesis: An International Delphi Survey
Conclusion: We established consensus among international fetal medicine experts on content to be included in a CVS/AC curriculum and on an assessment tool to evaluate CVS/AC skills. These results are important to help transition current training and assessment methods from a time- and volume-based approach to a competency-based approach which is a key step in improving patient safety and outcomes for the 2 most common invasive procedures in fetal medicine.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 8, 2021 Category: Perinatology & Neonatology Source Type: research

Amniocentesis and chorionic villus sampling: Green-top Guideline No. 8
BJOG. 2021 Oct 24. doi: 10.1111/1471-0528.16821. Online ahead of print.NO ABSTRACTPMID:34693616 | DOI:10.1111/1471-0528.16821 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: K Navaratnam Z Alfirevic Royal College of Obstetricians and Gynaecologists Source Type: research

Amniocentesis and chorionic villus sampling: Green-top Guideline No. 8
BJOG. 2021 Oct 24. doi: 10.1111/1471-0528.16821. Online ahead of print.NO ABSTRACTPMID:34693616 | DOI:10.1111/1471-0528.16821 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - October 25, 2021 Category: OBGYN Authors: K Navaratnam Z Alfirevic Royal College of Obstetricians and Gynaecologists Source Type: research

Effects of the implementation of second-line prenatal cell-free DNA testing on termination of pregnancy in a French perinatal network
CONCLUSION: The introduction of cfDNA testing does not increase the GA at termination for trisomy21.PMID:34689025 | DOI:10.1016/j.ejogrb.2021.10.002 (Source: Reproductive Biology)
Source: Reproductive Biology - October 24, 2021 Category: Reproduction Medicine Authors: Cl émence Duvillier Rodolphe Dard B érénice Hervé Camille Cohen Fran çois Vialard Thibaud Quibel Source Type: research

Effects of the implementation of second-line prenatal cell-free DNA testing on termination of pregnancy in a French perinatal network
CONCLUSION: The introduction of cfDNA testing does not increase the GA at termination for trisomy21.PMID:34689025 | DOI:10.1016/j.ejogrb.2021.10.002 (Source: Reproductive Biology)
Source: Reproductive Biology - October 24, 2021 Category: Reproduction Medicine Authors: Cl émence Duvillier Rodolphe Dard B érénice Hervé Camille Cohen Fran çois Vialard Thibaud Quibel Source Type: research

Fertility centers and cell-free fetal dna screening (cffdna): a review of maternit ® 21 plus performance in the reproductive health setting
Individuals who become pregnant through reproductive endocrinology and infertility (REI) often conceive by some type of fertility treatment. Patients who have experienced infertility or received fertility treatment, may have an aversion to chorionic villus sampling or amniocentesis because of the perceived risk associated with these procedures. Given the risk of procedure related pregnancy loss from these procedures patients may request cffDNA to provide additional information prior to deciding on diagnostic testing. (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2021 Category: Reproduction Medicine Authors: Vanessa Nitibhon, Brittany Dyr, Kimberly Ann Fanelli, Jill Rafalko Source Type: research

O-201 Prenatal and postnatal outcome of mosaic embryo transfers: multicentric study of one thousand mosaic embryos diagnosed by preimplantation genetic testing with trophectoderm biopsy
AbstractStudy questionTo explore the effect of chromosomal mosaicism detected in preimplantation genetic testing (PGT-A) on prenatal and postnatal outcome of mosaic embryo pregnanciesSummary answerNo significant difference between euploid and mosaic embryos was observed in terms of weeks of gestation, average weight, and developmental defect of the babies bornWhat is known alreadyMosaic embryos have the potential to implant and develop into healthy babies. Transfer of these embryos is now offered as an option for women who undergo IVF resulting in no euploid embryos. While, prenatal diagnosis has shown the depletion of chr...
Source: Human Reproduction - August 6, 2021 Category: Reproduction Medicine Source Type: research

Unselected CD117 Expression in Amniotic and Placental Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) have been extensively studied for over half a century. Their plasticity, self-renewal, and multilineage potential have generated unremitting interest in their use in regenerative therapy strategies. Fetal MSCs isolated from the amniotic fluid and placenta have been favored for perinatal applications largely because amniocentesis and chorionic villus sampling are minimally invasive and acceptably safe procedures. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - August 2, 2021 Category: Surgery Authors: Stefanie P Lazow, Ina Kycia, Sarah A Tracy, David Zurakowski, Dario O Fauza Source Type: research

Prenatal Invasive Testing at a Tertiary Referral Center in India: A Report of 433 Cases Under a Single Operator
ConclusionAneuploidy screening is the most common indication for prenatal invasive testing with dual marker combined with nuchal translucency, nasal bone, tricuspid regurgitation and ductus venosus flow providing the best detection rates. The chance of an affected fetus in a patient with aneuploidy screen positive overall is only 6.7%. (Source: The Journal of Obstetrics and Gynecology of India)
Source: The Journal of Obstetrics and Gynecology of India - June 8, 2021 Category: OBGYN Source Type: research

Fetal loss after chorionic villus sampling in twin pregnancies
CONCLUSION: The 2-fold increased risk of fetal loss following CVS in twin pregnancies can to a great extent be explained by maternal and pregnancy characteristics rather than the invasive procedure itself. This article is protected by copyright. All rights reserved.PMID:34038977 | DOI:10.1002/uog.23694 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - May 26, 2021 Category: Radiology Authors: T Elger R Akolekar A Syngelaki C De Paco Matallana F S Molina M Gallardo Arozena P Chaveeva N Persico V Accurti O Kagan N Prodan J Cruz K H Nicolaides Source Type: research

Fetal loss after chorionic villus sampling in twin pregnancies
CONCLUSION: The 2-fold increased risk of fetal loss following CVS in twin pregnancies can to a great extent be explained by maternal and pregnancy characteristics rather than the invasive procedure itself. This article is protected by copyright. All rights reserved.PMID:34038977 | DOI:10.1002/uog.23694 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - May 26, 2021 Category: Radiology Authors: T Elger R Akolekar A Syngelaki C De Paco Matallana F S Molina M Gallardo Arozena P Chaveeva N Persico V Accurti O Kagan N Prodan J Cruz K H Nicolaides Source Type: research