Examination of a Stillbirth Workup: A Rural Statewide Experience
CONCLUSIONS: Fetal stillbirth assessment is suboptimal in our rural state, with 15% of stillbirths having no assessment and only 2% having all four assessments. There is no association between stillbirth assessment and gestational age (<28 weeks vs >28 weeks), but there is a correlation between delivery volume and stillbirth assessment.PMID:36318947 | PMC:PMC9634678 | DOI:10.14423/SMJ.0000000000001471 (Source: Southern Medical Journal)
Source: Southern Medical Journal - November 1, 2022 Category: General Medicine Authors: Dayna D Whitcombe Everett F Magann Emily C Fahr Abigail Ramseyer Songthip Ounpraseuth Wendy N Nembhard Source Type: research
GSE211429 Single-cell atlas of patient-derived trophoblast organoids (TO) in on-going pregnancies.
This study demonstrates the utility of trophoblast organoids for investigating genetic defects in the placenta and describes an experimental platform for future personalized placental medicine approaches, including genotype-phenotype mapping. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - October 1, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Prenatal diagnosis of cystic hygroma cases in a tertiary centre and retrospective analysis of pregnancy results
J Obstet Gynaecol. 2022 Aug 25:1-6. doi: 10.1080/01443615.2022.2112023. Online ahead of print.ABSTRACTThe aim of this study is to retrospectively examine invasive diagnostic methods, structural anomalies accompanying cystic hygroma, and pregnancy outcomes in cystic hygroma cases admitted to a tertiary centre. The population of the study consisted of 29 live foetuses with cystic hygroma in the foetal neck only in the first or second trimester. In the study, pregnant women who applied to our centre were included. Amniocentesis or chorionic villus sampling was performed for genetic analysis according to the weeks of the pregn...
Source: Journal of Obstetrics and Gynaecology - August 25, 2022 Category: OBGYN Authors: Sureyya Saridas Demir Erkan Cagliyan Derya Öztürk Samican Özmen Sabahattin Altunyurt Tufan Çankaya Elcin Bora Source Type: research
Analysis results of 169 cases of chorionic villus samples of missed abortion using high throughput sequencing
CONCLUSIONS: (1) Chromosomal abnormality is an important cause of missed abortion, it majorly includes chromosomal numerical abnormality, of which most cases are of aneuploidy. (2) Advanced age may increase the risk of embryonic chromosomal abnormalities. (3) Villus chromosome detection using HTS has a positive value and can be used for analyzing and determining the causes of missed abortion.PMID:35993646 | DOI:10.26355/eurrev_202208_29419 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - August 22, 2022 Category: Drugs & Pharmacology Authors: L Deng H-F Chen J-Y Su B-H Gui X-D Wei J-R Tong Y Chen P Xu J Cai A-H Xia L-F Tang X-X Li J-Y Lan Y-L Wang Y Huang Source Type: research
Analysis results of 169 cases of chorionic villus samples of missed abortion using high throughput sequencing
CONCLUSIONS: (1) Chromosomal abnormality is an important cause of missed abortion, it majorly includes chromosomal numerical abnormality, of which most cases are of aneuploidy. (2) Advanced age may increase the risk of embryonic chromosomal abnormalities. (3) Villus chromosome detection using HTS has a positive value and can be used for analyzing and determining the causes of missed abortion.PMID:35993646 | DOI:10.26355/eurrev_202208_29419 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - August 22, 2022 Category: Drugs & Pharmacology Authors: L Deng H-F Chen J-Y Su B-H Gui X-D Wei J-R Tong Y Chen P Xu J Cai A-H Xia L-F Tang X-X Li J-Y Lan Y-L Wang Y Huang Source Type: research
