Identification of potential anti-inflammatory components in Moutan Cortex by bio-affinity ultrafiltration coupled with ultra-performance liquid chromatography mass spectrometry
In conclusion, BAUF-UPLC-MS combining the molecular docking is an efficient approach to discover enzyme inhibitors from traditional herbs and understand the mechanism of action.PMID:38384290 | PMC:PMC10880116 | DOI:10.3389/fphar.2024.1358640 (Source: Cancer Control)
Source: Cancer Control - February 22, 2024 Category: Cancer & Oncology Authors: Caomin Zou Qianru Chen Jiasheng Li Xiguang Lin Xingyang Xue Xinhang Cai Yicheng Chen Yue Sun Shumei Wang Ying Zhang Jiang Meng Source Type: research
Antioxidant and Anti-Arthritic Activity of Bombax buonopozense P. Beauv. Leaves
CONCLUSION: Phytochemical screening revealed the presence of flavonoids, alkaloids, and phenolics. The brine shrimp lethality assay of the crude extract and fractions gave LC50 value ≥ 1000 µg/mL, compared to Cyclophosphamide (LC50 = 224.7±0.35µg/mL). The BBME had TPC value of 19.8±0.56 mg GAE/g, while the TFC of ethyl acetate fraction was the highest (173.5±0.05 mg QE/g). The ethyl acetate fraction has the highest antioxidant activity (IC50 = 20.96±0.23 µg/mL) as compared to ascorbic acid (2.8±0.01) and rutin (20.6±9.26 µg/mL). BBME significantly reduced the paw circumference. BBME (400 mg/kg) prevented bioche...
Source: Annales Pharmaceutiques Francaises - February 17, 2024 Category: Drugs & Pharmacology Authors: Olusoji Aanuoluwa Fadogba Akingbolabo Daniel Ogunlakin Abayomi Mayowa Ajayi Mubo Adeola Sonibare Source Type: research
Antioxidant and Anti-Arthritic Activity of Bombax buonopozense P. Beauv. Leaves
CONCLUSION: Phytochemical screening revealed the presence of flavonoids, alkaloids, and phenolics. The brine shrimp lethality assay of the crude extract and fractions gave LC50 value ≥ 1000 µg/mL, compared to Cyclophosphamide (LC50 = 224.7±0.35µg/mL). The BBME had TPC value of 19.8±0.56 mg GAE/g, while the TFC of ethyl acetate fraction was the highest (173.5±0.05 mg QE/g). The ethyl acetate fraction has the highest antioxidant activity (IC50 = 20.96±0.23 µg/mL) as compared to ascorbic acid (2.8±0.01) and rutin (20.6±9.26 µg/mL). BBME significantly reduced the paw circumference. BBME (400 mg/kg) prevented bioche...
Source: Annales Pharmaceutiques Francaises - February 17, 2024 Category: Drugs & Pharmacology Authors: Olusoji Aanuoluwa Fadogba Akingbolabo Daniel Ogunlakin Abayomi Mayowa Ajayi Mubo Adeola Sonibare Source Type: research
Antioxidant and Anti-Arthritic Activity of Bombax buonopozense P. Beauv. Leaves
CONCLUSION: Phytochemical screening revealed the presence of flavonoids, alkaloids, and phenolics. The brine shrimp lethality assay of the crude extract and fractions gave LC50 value ≥ 1000 µg/mL, compared to Cyclophosphamide (LC50 = 224.7±0.35µg/mL). The BBME had TPC value of 19.8±0.56 mg GAE/g, while the TFC of ethyl acetate fraction was the highest (173.5±0.05 mg QE/g). The ethyl acetate fraction has the highest antioxidant activity (IC50 = 20.96±0.23 µg/mL) as compared to ascorbic acid (2.8±0.01) and rutin (20.6±9.26 µg/mL). BBME significantly reduced the paw circumference. BBME (400 mg/kg) prevented bioche...
Source: Annales Pharmaceutiques Francaises - February 17, 2024 Category: Drugs & Pharmacology Authors: Olusoji Aanuoluwa Fadogba Akingbolabo Daniel Ogunlakin Abayomi Mayowa Ajayi Mubo Adeola Sonibare Source Type: research
Antioxidant and Anti-Arthritic Activity of Bombax buonopozense P. Beauv. Leaves
CONCLUSION: Phytochemical screening revealed the presence of flavonoids, alkaloids, and phenolics. The brine shrimp lethality assay of the crude extract and fractions gave LC50 value ≥ 1000 µg/mL, compared to Cyclophosphamide (LC50 = 224.7±0.35µg/mL). The BBME had TPC value of 19.8±0.56 mg GAE/g, while the TFC of ethyl acetate fraction was the highest (173.5±0.05 mg QE/g). The ethyl acetate fraction has the highest antioxidant activity (IC50 = 20.96±0.23 µg/mL) as compared to ascorbic acid (2.8±0.01) and rutin (20.6±9.26 µg/mL). BBME significantly reduced the paw circumference. BBME (400 mg/kg) prevented bioche...
Source: Annales Pharmaceutiques Francaises - February 17, 2024 Category: Drugs & Pharmacology Authors: Olusoji Aanuoluwa Fadogba Akingbolabo Daniel Ogunlakin Abayomi Mayowa Ajayi Mubo Adeola Sonibare Source Type: research
Antioxidant and Anti-Arthritic Activity of Bombax buonopozense P. Beauv. Leaves
CONCLUSION: Phytochemical screening revealed the presence of flavonoids, alkaloids, and phenolics. The brine shrimp lethality assay of the crude extract and fractions gave LC50 value ≥ 1000 µg/mL, compared to Cyclophosphamide (LC50 = 224.7±0.35µg/mL). The BBME had TPC value of 19.8±0.56 mg GAE/g, while the TFC of ethyl acetate fraction was the highest (173.5±0.05 mg QE/g). The ethyl acetate fraction has the highest antioxidant activity (IC50 = 20.96±0.23 µg/mL) as compared to ascorbic acid (2.8±0.01) and rutin (20.6±9.26 µg/mL). BBME significantly reduced the paw circumference. BBME (400 mg/kg) prevented bioche...
Source: Annales Pharmaceutiques Francaises - February 17, 2024 Category: Drugs & Pharmacology Authors: Olusoji Aanuoluwa Fadogba Akingbolabo Daniel Ogunlakin Abayomi Mayowa Ajayi Mubo Adeola Sonibare Source Type: research
Erratum: [Corrigendum] PF ‑2341066 combined with celecoxib promotes apoptosis and inhibits proliferation in human cholangiocarcinoma QBC939 cells
Exp Ther Med. 2024 Jan 24;27(3):111. doi: 10.3892/etm.2024.12399. eCollection 2024 Mar.ABSTRACT[This corrects the article DOI: 10.3892/etm.2018.5967.].PMID:38361523 | PMC:PMC10867725 | DOI:10.3892/etm.2024.12399 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - February 16, 2024 Category: General Medicine Authors: Chen Chen Qinghua Zeng Liang Luo Chengzhi Cai Source Type: research
