Fight Aging! Newsletter, October 15th 2018
This study suggests that exocrine glands can be induced from pluripotent stem cells for organ replacement regenerative therapy.
Replacement of Aged Microglia Partially Reverses Cognitive Decline in Mice
https://www.fightaging.org/archives/2018/10/replacement-of-aged-microglia-partially-reverses-cognitive-decline-in-mice/
Researchers here report on a compelling demonstration that shows the degree to which dysfunctional microglia contribute to age-related neurodegeneration. The scientists use a pharmacological approach to greatly deplete the microglial population and then allow it to recover naturally. Th...
Source: Fight Aging! - October 14, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
HOW TO Support Patient Education Through Technologies?
There’s nothing new about an information-savvy patient. The novelty is the array of digital technologies and internet-based communication tools aiming at appeasing that appetite beyond just asking doctors for advice. How could medical professionals help their patients understand the most possible about diseases, drugs, treatments and alternative care with the help of innovative means? Here’s our overview.
Like it or not, patients google symptoms
One of the most visible consequences of digital health is the change in the relationship between patients and doctors. The latter are not the exclusive source of medical inform...
Source: The Medical Futurist - October 2, 2018 Category: Information Technology Authors: nora Tags: Empowered Patients From Chance to Choice Healthcare Design Medical Professionals Social media in Healthcare communication digital digital health doctor-patient doctor-patient relationship future health communication patient educati Source Type: blogs
Fight Aging! Newsletter, September 17th 2018
In this study, we found that TXNIP deficiency induces accelerated senescent phenotypes of mouse embryonic fibroblast (MEF) cells under high glucose condition and that the induction of cellular ROS or AKT activation is critical for cellular senescence. Our results also revealed that TXNIP inhibits AKT activity by a direct interaction, which is upregulated by high glucose and H2O2 treatment. In addition, TXNIP knockout mice exhibited an increase in glucose uptake and aging-associated phenotypes including a decrease in energy metabolism and induction of cellular senescence and aging-associated gene expression. We propose that...
Source: Fight Aging! - September 16, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
National Ophthalmology Database Audit: year 3 annual report
Healthcare Quality Improvement Partnership - HQIP has commissioned the National Ophthalmology Database (NOD) cataract audit to report on all NHS funded cataract surgery in England and Wales. Included in this second prospective report are operations undertaken between 1st September 2016 and 31st August 2017.ReportMore detail (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - August 13, 2018 Category: UK Health Authors: The King ' s Fund Information & Knowledge Service Tags: Quality of care and clinical outcomes Source Type: blogs
Dry Eye: An Interview With Corneal Specialist Dr. Peter Polack
I met ophthalmologist and corneal specialist Dr. Peter Polack while speaking in Ocala, Florida. He told me that, by having his patients with dry eye—which has increased dramatically over the last 20 years—remove all wheat and grains, he is seeing this condition reverse within weeks, along with all the other health benefits.
Unlike other ophthalmologists, who virtually have nothing to do with diet and therefore prescribe the costly drugs Restasis and Xiidra (each cost $500-$550 per month), Dr. Polack rarely has to resort to use of these awful agents.
Here Dr. Polack speaks about his phenomenal experience.
More a...
Source: Wheat Belly Blog - July 20, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates autoimmune dry eye gluten-free grain-free grains Inflammation restasis undoctored wheat belly xiidra Source Type: blogs
Glaukos iStent Inject Implant FDA Approved to Treat Primary Open-Angle Glaucoma
Glaukos, based in San Clemente, California, won FDA approval to introduce its iStent inject Trabecular Micro-Bypass System in the United States. The device, designed to treat mild to moderate primary open-angle glaucoma, is implanted alongside cataract surgeries to reduce intraocular pressure.
The implant is tiny, measuring only 0.23 mm x 0.36 mm, and Glaukos believes it is the smallest device ever approved by the FDA. It’s positioned to allow for fluid to move through the trabecular meshwork, producing flow in both direction within the Schlemm’s canal.
Some details about the study that led to the approva...
Source: Medgadget - July 17, 2018 Category: Medical Devices Authors: Editors Tags: Ophthalmology Source Type: blogs
Look what happened to Leslie with Wheat Belly + L. reuteri
Leslie has been following the entire Wheat Belly lifestyle with breathtaking results to show for it. More recently, based on our numerous conversations here and elsewhere, she added L. reuteri. Interestingly, although all the skin health and anti-aging benefits have been observed only with the ATCC PTA 6475 and DSM 17938 strains, Leslie took the UALre-16 strain from Nature’s Way, suggesting that this strain may also boost oxytocin and thereby provide all the skin and health benefits of the other strains.
“Many are asking what change I’ve made in my makeup as my skin looks so smooth. I lost 40 lbs ...
Source: Wheat Belly Blog - July 3, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates anti-aging oxytocin prebiotic probiotic reuteri undoctored Weight Loss wheat belly Source Type: blogs
Fight Aging! Newsletter, June 25th 2018
In this study, we investigate mitochondrial energetics and mtDNA methylation in senescent cells, and evaluate the potential of humanin and MOTS-c as novel senolytics or SASP modulators that can alleviate symptoms of frailty and extend health span by targeting mitochondrial bioenergetics.
Exercise versus the Hallmarks of Aging
https://www.fightaging.org/archives/2018/06/exercise-versus-the-hallmarks-of-aging/
The paper I'll point out today walks through the ways in which exercise is known to beneficially affect the Hallmarks of Aging. The Hallmarks are a list of the significant causes of aging that I di...
Source: Fight Aging! - June 24, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
CD36 as a Potentially Important Marker and Mechanism in Cellular Senescence
In this study, we conducted comparative RNAseq experiments to detect genes associated with replicative senescence in two different human fibroblast cell lines and at different time points. We identified 841 and 900 genes (core senescence-associated genes) that are significantly up- and downregulated in senescent cells, respectively, in both cell lines.
Our functional enrichment analysis showed that downregulated core genes are primarily involved in cell cycle processes while upregulated core gene enrichment indicated various lipid-related processes. We further demonstrated that downregulated genes are significantly ...
Source: Fight Aging! - June 22, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Why cataract surgery is more complicated than it should be
Eye surgery is a delicate business. It involves operating within an orb the size of a large marble to remove a cataract or repair a retinal detachment.
Not only is superb eye-hand coordination a must, but also an awareness of the myriad other medical issues in the elderly population most in need of eye surgery.
Traditionally, patients undergoing cataract surgery had a preoperative medical evaluation, including blood work, chest X-ray, and EKG, to determine their suitability for surgery. This is a remnant from the days when cataract surgery was a long operation with a week of hospitalization and bed rest.
Continue reading ....
Source: Kevin, M.D. - Medical Weblog - April 9, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/brian-c-joondeph" rel="tag" > Brian C. Joondeph, MD < /a > Tags: Policy Ophthalmology Surgery Source Type: blogs
Notes from WIRED Health 2018 at Francis Crick Institute
Set in its new home of the Francis Crick Institute, WIRED Health 2018 brought together world leaders and change-makers in cancer, aging, artificial intelligence, government, medical devices, and pharmaceuticals, to name but a few. Alongside the main event, cutting-edge medtech companies demonstrated their new technologies, and budding start-ups pitched for the chance to be crowned WIRED Health start-up of the year.
Bruce Levine from the University of Pennsylvania opened the day by setting the challenge of how to treat a condition like cancer, which is fundamentally the result of “our own bodies gone awry.” Bruce intro...
Source: Medgadget - March 16, 2018 Category: Medical Devices Authors: Tom Peach Tags: Exclusive Source Type: blogs
Interesting things about traveling
He had a very hard time adjusting to altitude changes. I thought that was interesting. The higher the altitude, the more nitroglycerin he took and the more difficulty he had breathing. I don't think either of us were prepared for that.Temperature changes affected him as well. If he got cold, he put on gloves....and I'd be so hot I'd have the AC on blast!Almost a comedy of errors. He worried constantly about having enough insulin. I reassured him that we were never more than 3 or 4 days from home and could start back any time he wanted.We were gone almost a month. I loved every moment of ...
Source: Wife of a Diabetic - March 9, 2018 Category: Endocrinology Source Type: blogs
Understanding the Cataract Phenomenon in Radiology Techs
As nuclear medicine (NM) procedures have become more popular in U.S. hospitals, radiology technologists are at increasing risk for developing a cataract. According to anew study published inRadiology, this ionizing radiation technology that ’s used to evaluate organ health and treat disease can cause damage to technologists’ eyes. Between the years 2003 and 2005, and 2012 and 2013, a group of researchers from the National Cancer Institute, the University of Minnesota, and the American Registry of Radiologic Technologists surveyed 42,545 radiologic technologists about their work history, eye health, lifestyle, their use...
Source: radRounds - February 10, 2018 Category: Radiology Authors: Julie Morse Source Type: blogs
Carb Loading: Outdated and Dangerous
It has become a familiar scene at athletic events: sugar and carb-fests before and during marathons, triathlons, swimming competitions, and other sports among amateurs and professionals, even high school athletes and grade school soccer players. They do it for energy and enhanced athletic performance, having been told that loading up on carbs is the ticket to winning.
This common practice is based on decades-old flawed studies that reported that athletes experienced reduced performance when deprived of carbohydrates, performance restored upon restoration of carbohydrates. Thus was born the notion of “carb-loading” (i.e...
Source: Wheat Belly Blog - January 22, 2018 Category: Cardiology Authors: Dr. Davis Tags: BLOOD SUGAR Car Loading Carbohydrates Undoctored Wheat Belly Wheat Belly Lifestyle Wheat Belly/Undoctored Cruise carb loading Dr. Davis exercise Wheat Belly Total Health Source Type: blogs
