Effects of root-derived organic acids on sorption of pharmaceutically active compounds in sandy topsoil
Chemosphere. 2024 Mar 24:141759. doi: 10.1016/j.chemosphere.2024.141759. Online ahead of print.ABSTRACTThe presence and fate of pharmaceutically active compounds (PhACs) in agricultural fields are rarely investigated. The present study highlights that root-derived low-molecular-weight organic acids (LWMOAs) affect the mobility of PhACs in cultivated humic Arenosol. Sorption experiments are conducted using three PhACs characterised by different physicochemical properties: carbamazepine (CBZ), 17α-ethinylestradiol (EE2), and diclofenac-sodium (DFC). The results suggest that the adsorption of EE2 is more intense than the oth...
Source: Chemosphere - March 26, 2024 Category: Chemistry Authors: Lili Szabo Anna Vancsik Laszlo Bauer Gergely Jakab Csilla Kiraly Istvan Hatvani Attila Csaba Kondor Zoltan Szalai Source Type: research
Effects of root-derived organic acids on sorption of pharmaceutically active compounds in sandy topsoil
Chemosphere. 2024 Mar 24:141759. doi: 10.1016/j.chemosphere.2024.141759. Online ahead of print.ABSTRACTThe presence and fate of pharmaceutically active compounds (PhACs) in agricultural fields are rarely investigated. The present study highlights that root-derived low-molecular-weight organic acids (LWMOAs) affect the mobility of PhACs in cultivated humic Arenosol. Sorption experiments are conducted using three PhACs characterised by different physicochemical properties: carbamazepine (CBZ), 17α-ethinylestradiol (EE2), and diclofenac-sodium (DFC). The results suggest that the adsorption of EE2 is more intense than the oth...
Source: Chemosphere - March 26, 2024 Category: Chemistry Authors: Lili Szabo Anna Vancsik Laszlo Bauer Gergely Jakab Csilla Kiraly Istvan Hatvani Attila Csaba Kondor Zoltan Szalai Source Type: research
Effects of root-derived organic acids on sorption of pharmaceutically active compounds in sandy topsoil
Chemosphere. 2024 Mar 24:141759. doi: 10.1016/j.chemosphere.2024.141759. Online ahead of print.ABSTRACTThe presence and fate of pharmaceutically active compounds (PhACs) in agricultural fields are rarely investigated. The present study highlights that root-derived low-molecular-weight organic acids (LWMOAs) affect the mobility of PhACs in cultivated humic Arenosol. Sorption experiments are conducted using three PhACs characterised by different physicochemical properties: carbamazepine (CBZ), 17α-ethinylestradiol (EE2), and diclofenac-sodium (DFC). The results suggest that the adsorption of EE2 is more intense than the oth...
Source: Chemosphere - March 26, 2024 Category: Chemistry Authors: Lili Szabo Anna Vancsik Laszlo Bauer Gergely Jakab Csilla Kiraly Istvan Hatvani Attila Csaba Kondor Zoltan Szalai Source Type: research
Effects of root-derived organic acids on sorption of pharmaceutically active compounds in sandy topsoil
Chemosphere. 2024 Mar 24:141759. doi: 10.1016/j.chemosphere.2024.141759. Online ahead of print.ABSTRACTThe presence and fate of pharmaceutically active compounds (PhACs) in agricultural fields are rarely investigated. The present study highlights that root-derived low-molecular-weight organic acids (LWMOAs) affect the mobility of PhACs in cultivated humic Arenosol. Sorption experiments are conducted using three PhACs characterised by different physicochemical properties: carbamazepine (CBZ), 17α-ethinylestradiol (EE2), and diclofenac-sodium (DFC). The results suggest that the adsorption of EE2 is more intense than the oth...
Source: Chemosphere - March 26, 2024 Category: Chemistry Authors: Lili Szabo Anna Vancsik Laszlo Bauer Gergely Jakab Csilla Kiraly Istvan Hatvani Attila Csaba Kondor Zoltan Szalai Source Type: research
The Effect of Levetiracetam Compared with Enzyme-Inducing Antiseizure Medications on Apixaban and Rivaroxaban Peak Plasma Concentrations
ConclusionsIn this study, we show that unlike EI-ASMs, LEV clinical use was not significantly associated with lower apixabanCmax and was similar to that in patients not treated with any ASM. Our findings suggest that the combination of LEV with apixaban and rivaroxaban may not be associated with decreased apixaban and rivaroxabanCmax. Therefore, prospective controlled studies are required to examine the possible non-pharmacokinetic mechanism of the effect of the LEV-apixaban or LEV-rivaroxaban combination on patients ’ outcomes. (Source: CNS Drugs)
Source: CNS Drugs - March 23, 2024 Category: Neurology Source Type: research
Hemimasticatory spasm: a series of 17 cases and a comprehensive review of the literature
In conclusion, highly effective modalities are currently available, and it is necessary to raise awareness of HMS to ensure that it can be diagnosed and treated accurately by both medical and dental professionals. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 18, 2024 Category: Neurology Source Type: research
Increased Cyclic Adenosine Monophosphate Responsive Element is Closely Associated with the Pathogenesis of Drug-resistant Epilepsy
CONCLUSION: Our study shows that enhanced CREB expression promotes the development of DRE and negatively regulates GABAA receptor levels and that the inhibition of CREB expression may reduce the incidence of DRE.PMID:38468526 | DOI:10.2174/0115672026290996240307072539 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - March 12, 2024 Category: Neurology Authors: Jing-Xuan Li Dai Shi Si-Ying Ren Guo-Feng Wu Source Type: research
Increased Cyclic Adenosine Monophosphate Responsive Element is Closely Associated with the Pathogenesis of Drug-resistant Epilepsy
CONCLUSION: Our study shows that enhanced CREB expression promotes the development of DRE and negatively regulates GABAA receptor levels and that the inhibition of CREB expression may reduce the incidence of DRE.PMID:38468526 | DOI:10.2174/0115672026290996240307072539 (Source: Epilepsy Curr)
Source: Epilepsy Curr - March 12, 2024 Category: Neurology Authors: Jing-Xuan Li Dai Shi Si-Ying Ren Guo-Feng Wu Source Type: research
Trigeminal neuralgia secondary to epidermoid cyst and neurovascular conflict: An illustrative case with literature review
CONCLUSION: TN secondary to EC in association with a NVC is a rare phenomenon, due to the growth pattern of the EC. TN may remit if an appropriate treatment is carried out. In cases of NVC, an MVD is required apart from an appropriate resection to achieve pain relief.PMID:38468668 | PMC:PMC10927216 | DOI:10.25259/SNI_925_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - March 12, 2024 Category: Neurosurgery Authors: Rogelio Revuelta-Guti érrez Oscar Rub én Contreras-Vázquez Fernando Pi ñón-Jiménez Jaime Jes ús Martínez-Anda Source Type: research
Increased Cyclic Adenosine Monophosphate Responsive Element is Closely Associated with the Pathogenesis of Drug-resistant Epilepsy
CONCLUSION: Our study shows that enhanced CREB expression promotes the development of DRE and negatively regulates GABAA receptor levels and that the inhibition of CREB expression may reduce the incidence of DRE.PMID:38468526 | DOI:10.2174/0115672026290996240307072539 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - March 12, 2024 Category: Neurology Authors: Jing-Xuan Li Dai Shi Si-Ying Ren Guo-Feng Wu Source Type: research
Increased Cyclic Adenosine Monophosphate Responsive Element is Closely Associated with the Pathogenesis of Drug-resistant Epilepsy
CONCLUSION: Our study shows that enhanced CREB expression promotes the development of DRE and negatively regulates GABAA receptor levels and that the inhibition of CREB expression may reduce the incidence of DRE.PMID:38468526 | DOI:10.2174/0115672026290996240307072539 (Source: Epilepsy Curr)
Source: Epilepsy Curr - March 12, 2024 Category: Neurology Authors: Jing-Xuan Li Dai Shi Si-Ying Ren Guo-Feng Wu Source Type: research
Trigeminal neuralgia secondary to epidermoid cyst and neurovascular conflict: An illustrative case with literature review
CONCLUSION: TN secondary to EC in association with a NVC is a rare phenomenon, due to the growth pattern of the EC. TN may remit if an appropriate treatment is carried out. In cases of NVC, an MVD is required apart from an appropriate resection to achieve pain relief.PMID:38468668 | PMC:PMC10927216 | DOI:10.25259/SNI_925_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - March 12, 2024 Category: Neurosurgery Authors: Rogelio Revuelta-Guti érrez Oscar Rub én Contreras-Vázquez Fernando Pi ñón-Jiménez Jaime Jes ús Martínez-Anda Source Type: research
Increased Cyclic Adenosine Monophosphate Responsive Element is Closely Associated with the Pathogenesis of Drug-resistant Epilepsy
CONCLUSION: Our study shows that enhanced CREB expression promotes the development of DRE and negatively regulates GABAA receptor levels and that the inhibition of CREB expression may reduce the incidence of DRE.PMID:38468526 | DOI:10.2174/0115672026290996240307072539 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - March 12, 2024 Category: Neurology Authors: Jing-Xuan Li Dai Shi Si-Ying Ren Guo-Feng Wu Source Type: research
Increased Cyclic Adenosine Monophosphate Responsive Element is Closely Associated with the Pathogenesis of Drug-resistant Epilepsy
CONCLUSION: Our study shows that enhanced CREB expression promotes the development of DRE and negatively regulates GABAA receptor levels and that the inhibition of CREB expression may reduce the incidence of DRE.PMID:38468526 | DOI:10.2174/0115672026290996240307072539 (Source: Epilepsy Curr)
Source: Epilepsy Curr - March 12, 2024 Category: Neurology Authors: Jing-Xuan Li Dai Shi Si-Ying Ren Guo-Feng Wu Source Type: research
Trigeminal neuralgia secondary to epidermoid cyst and neurovascular conflict: An illustrative case with literature review
CONCLUSION: TN secondary to EC in association with a NVC is a rare phenomenon, due to the growth pattern of the EC. TN may remit if an appropriate treatment is carried out. In cases of NVC, an MVD is required apart from an appropriate resection to achieve pain relief.PMID:38468668 | PMC:PMC10927216 | DOI:10.25259/SNI_925_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - March 12, 2024 Category: Neurosurgery Authors: Rogelio Revuelta-Guti érrez Oscar Rub én Contreras-Vázquez Fernando Pi ñón-Jiménez Jaime Jes ús Martínez-Anda Source Type: research
