Cost-effectiveness analysis of HLA-B*15:02 screening before treatment of epilepsy in Indonesia
CONCLUSION: Calculation of the cost-effectiveness of lifetime epilepsy therapy in this study found that the initial screening strategy with the HLA-B*15:02 test was the most cost-effective.PMID:38657484 | DOI:10.1016/j.yebeh.2024.109787 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - April 24, 2024 Category: Neurology Authors: Eric Tanoto Herlyani Khosama Seilly Jehosua Sekplin A S Sekeon Winifred Karema Arthur H P Mawuntu Fima F L G Langi Lim Kheng Seang Source Type: research
Evaluation of anti-seizure medications and their serum concentration with regard to cardiovascular risk parameters: A cross-sectional study
CONCLUSION: In our study, the majority of patients were children and adolescents. Regular monitoring of drug serum concentrations and metabolic parameters may be useful to select the safest drug in terms of cardiovascular disease risk. Randomized controlled trials on the long-term effects of anti-seizure treatment are needed.PMID:38657483 | DOI:10.1016/j.yebeh.2024.109802 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - April 24, 2024 Category: Neurology Authors: Merve Becit-Kizilkaya Seyma Oncu Halit Bugra Koca Dilek Cavusoglu Source Type: research
Effect of zeolites on the reduction of the ecotoxicity of carbamazepine in the environment
In this study, the impact of calcination of zeolites on the ecotoxicity of carbamazepine solutions in two matrices, water and synthetic sewage, was assessed. Two types of zeolites were tested: natural zeolite, in the form of a zeolite rock consisting mainly of clinoptilolite, and a synthetic zeolite type 5 A. Additionally, zeolites were calcined at a temperature of 200 °C. The kinetics of carbamazepine adsorption in aqueous solutions and in synthetic sewage matrix was determined. Higher adsorption capacity was obtained for carbamazepine aqueous solutions as well as zeolites after the calcination process. Considering type ...
Source: Ecotoxicology and Environmental Safety - April 23, 2024 Category: Environmental Health Authors: Aleksandra Bogusz Beata Tomczyk Magdalena Trzci ńska Barbara Miros ław Barbara Gworek Source Type: research
Effect of zeolites on the reduction of the ecotoxicity of carbamazepine in the environment
In this study, the impact of calcination of zeolites on the ecotoxicity of carbamazepine solutions in two matrices, water and synthetic sewage, was assessed. Two types of zeolites were tested: natural zeolite, in the form of a zeolite rock consisting mainly of clinoptilolite, and a synthetic zeolite type 5 A. Additionally, zeolites were calcined at a temperature of 200 °C. The kinetics of carbamazepine adsorption in aqueous solutions and in synthetic sewage matrix was determined. Higher adsorption capacity was obtained for carbamazepine aqueous solutions as well as zeolites after the calcination process. Considering type ...
Source: Ecotoxicology and Environmental Safety - April 23, 2024 Category: Environmental Health Authors: Aleksandra Bogusz Beata Tomczyk Magdalena Trzci ńska Barbara Miros ław Barbara Gworek Source Type: research
Enzymatic and non-enzymatic removal of organic micropollutants with spent mushroom substrate of Agaricus bisporus
In this study, we assessed the removal of OMPs by spent mushroom substrate (SMS) of the white button mushroom (Agaricus bisporus) and by its aqueous tea extract. Removal of acesulfame K, antipyrine, bentazon, caffeine, carbamazepine, chloridazon, clofibric acid, and N, N-diethyl-meta-toluamide (DEET) by SMS and its tea was between 10 and 90% and 0-26%, respectively, in a 7-day period. Sorption to SMS particles was between 0 and 29%, which can thus not explain the removal difference between SMS and its tea, the latter lacking these particles. Carbamazepine was removed most efficiently by both SMS and its tea. Removal of OMP...
Source: Applied Microbiology and Biotechnology - April 19, 2024 Category: Microbiology Authors: Brigit van Brenk Fleur E L Kleijburg Antoine J B Kemperman Walter G J van der Meer Han A B W östen Source Type: research
Evaluating the prevalence and risk factors for depression in patients with temporal lobe epilepsy with hippocampal sclerosis: A cross-sectional multicenter study
CONCLUSION: We explored the differences in depression prevalence between TLE-HS and other epilepsy types and concluded they are minimal but slightly higher in TLE-HS. Predictors of depression such as seizure frequency and disease duration influenced MDD prevalence in TLE-HS. Lamotrigine and valproate were linked to higher NDDI-E scores.PMID:38636108 | DOI:10.1016/j.yebeh.2024.109782 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - April 18, 2024 Category: Neurology Authors: Bandar N Aljafen Ruwa Alneseyan Taim Muayqil Mashael O Alkhateeb Mubarak M Aldosari Aya Alsermani Lujain Alnakhli Renad Althomali Razan Alnami Ruba Alqahtani Lama Ibrahim Fawzi Babtain Source Type: research
Clinical effects of combined use of carbamazepine and amitriptyline in the treatment of diabetic neuropathy with concurrent diabetic foot
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 17, 2024 Category: Neuroscience Authors: Yi ChenLan LiuXiangjing KongJinshan SunHuijun LiXue ChangJianfang Chea Department of Anesthesiology, Nanjing Hospital of Chinese Medicine, Nanjing, Jiangsu, Chinab Department of Endocrinology, The Air Force Hospital from Eastern Theater of PLA, Nanjing, J Source Type: research
Environmental risk assessment of selected pharmaceuticals in hospital wastewater in nothern vietnam
This study investigated the occurrence of selected pharmaceuticals in influent and effluent of wastewater treatment plants of 12 hospitals in Hanoi and 3 northern cities of Vietnam during dry and rainy seasons. In addition, environmental risk of pharmaceuticals in both hospital influents and effluents were evaluated based on risk quotients (RQs). Nine selected pharmaceutical compounds including sulfamethoxazole (SMX), naproxen (NPX), diclofenac (DCF), ibuprofen (IBU), acetaminophen (ACT), carbamazepine (CBM), iopromide (IOP), atenolol (ATN), and caffeine (CAF) were frequently detected in most influent and effluent wastewat...
Source: Chemosphere - April 12, 2024 Category: Chemistry Authors: Anh T P Hoang Manh Cuong Do Kyoung-Woong Kim Source Type: research
Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research
Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: Pain Physician - April 4, 2024 Category: Anesthesiology Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research
Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research
Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research
Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research
Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research
Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research
