Stimulation of Secondary Metabolites and γ-Terpinene Synthase by Silver Nanoparticles in Callus Cultures of Carum carvi
Appl Biochem Biotechnol. 2022 Mar 29. doi: 10.1007/s12010-022-03879-8. Online ahead of print.ABSTRACTBiotechnology and nanotechnology are important tools for understanding biochemical pathways. They can be used efficiently for stimulating and increasing the production of secondary metabolites in medicinal plants. The present study aimed to identify the γ-terpinene synthase gene (CcTPS2) as an effective contributor to the biosynthetic pathway of monoterpenes. The effects of silver nanoparticles (AgNPs; 50 and 100 mg l- 1) and time (24 and 48 h) were examined on secondary metabolites in cell suspension cultures of Carum car...
Source: Applied Biochemistry and Biotechnology - March 29, 2022 Category: Biochemistry Authors: Zahra Dehghani-Aghchekohal Mansoor Omidi Reza Azizinezhad Alireza Etminan Source Type: research
Stimulation of Secondary Metabolites and γ-Terpinene Synthase by Silver Nanoparticles in Callus Cultures of Carum carvi
Appl Biochem Biotechnol. 2022 Mar 29. doi: 10.1007/s12010-022-03879-8. Online ahead of print.ABSTRACTBiotechnology and nanotechnology are important tools for understanding biochemical pathways. They can be used efficiently for stimulating and increasing the production of secondary metabolites in medicinal plants. The present study aimed to identify the γ-terpinene synthase gene (CcTPS2) as an effective contributor to the biosynthetic pathway of monoterpenes. The effects of silver nanoparticles (AgNPs; 50 and 100 mg l- 1) and time (24 and 48 h) were examined on secondary metabolites in cell suspension cultures of Carum car...
Source: Applied Biochemistry and Biotechnology - March 29, 2022 Category: Biochemistry Authors: Zahra Dehghani-Aghchekohal Mansoor Omidi Reza Azizinezhad Alireza Etminan Source Type: research
Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration
CONCLUSIONS: PPL mimics PDAC clinically and radiologically and could be a challenge for pathologic diagnosis if lymphoma is not included in the differential diagnosis during immediate evaluation. If lymphoma is suspected during immediate evaluation, PPL could be reliably diagnosed by FNA with the aid of ancillary studies.PMID:35311939 | DOI:10.1093/ajcp/aqac030 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2022 Category: Pathology Authors: Qiong Gan Nancy P Caraway Cady Ding John M Stewart Source Type: research
Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration
CONCLUSIONS: PPL mimics PDAC clinically and radiologically and could be a challenge for pathologic diagnosis if lymphoma is not included in the differential diagnosis during immediate evaluation. If lymphoma is suspected during immediate evaluation, PPL could be reliably diagnosed by FNA with the aid of ancillary studies.PMID:35311939 | DOI:10.1093/ajcp/aqac030 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2022 Category: Pathology Authors: Qiong Gan Nancy P Caraway Cady Ding John M Stewart Source Type: research
Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration
CONCLUSIONS: PPL mimics PDAC clinically and radiologically and could be a challenge for pathologic diagnosis if lymphoma is not included in the differential diagnosis during immediate evaluation. If lymphoma is suspected during immediate evaluation, PPL could be reliably diagnosed by FNA with the aid of ancillary studies.PMID:35311939 | DOI:10.1093/ajcp/aqac030 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2022 Category: Pathology Authors: Qiong Gan Nancy P Caraway Cady Ding John M Stewart Source Type: research
Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration
CONCLUSIONS: PPL mimics PDAC clinically and radiologically and could be a challenge for pathologic diagnosis if lymphoma is not included in the differential diagnosis during immediate evaluation. If lymphoma is suspected during immediate evaluation, PPL could be reliably diagnosed by FNA with the aid of ancillary studies.PMID:35311939 | DOI:10.1093/ajcp/aqac030 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2022 Category: Pathology Authors: Qiong Gan Nancy P Caraway Cady Ding John M Stewart Source Type: research
Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration
CONCLUSIONS: PPL mimics PDAC clinically and radiologically and could be a challenge for pathologic diagnosis if lymphoma is not included in the differential diagnosis during immediate evaluation. If lymphoma is suspected during immediate evaluation, PPL could be reliably diagnosed by FNA with the aid of ancillary studies.PMID:35311939 | DOI:10.1093/ajcp/aqac030 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2022 Category: Pathology Authors: Qiong Gan Nancy P Caraway Cady Ding John M Stewart Source Type: research
Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration
CONCLUSIONS: PPL mimics PDAC clinically and radiologically and could be a challenge for pathologic diagnosis if lymphoma is not included in the differential diagnosis during immediate evaluation. If lymphoma is suspected during immediate evaluation, PPL could be reliably diagnosed by FNA with the aid of ancillary studies.PMID:35311939 | DOI:10.1093/ajcp/aqac030 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2022 Category: Pathology Authors: Qiong Gan Nancy P Caraway Cady Ding John M Stewart Source Type: research
Primary Pancreatic Lymphoma Evaluated by Fine-Needle Aspiration
CONCLUSIONS: PPL mimics PDAC clinically and radiologically and could be a challenge for pathologic diagnosis if lymphoma is not included in the differential diagnosis during immediate evaluation. If lymphoma is suspected during immediate evaluation, PPL could be reliably diagnosed by FNA with the aid of ancillary studies.PMID:35311939 | DOI:10.1093/ajcp/aqac030 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - March 21, 2022 Category: Pathology Authors: Qiong Gan Nancy P Caraway Cady Ding John M Stewart Source Type: research
POSA120 Healthcare Resource Utilization in Patients with Painful Diabetic Neuropathy Treated with 10-Khz Spinal Cord Stimulation: Results from a Randomized Controlled Trial
Painful diabetic neuropathy (PDN) affects around 20% of people with diabetes and is associated with higher healthcare resource utilization (HRU) compared with non-PDN patients with diabetes (Mehra 2014; Kiyani 2020). Conventional medical management (CMM) includes pharmacotherapy, which has limited efficacy and adverse side effects. High-frequency 10-kHz spinal cord stimulation (SCS) has demonstrated significant pain reduction in individuals with refractory PDN in a safe and effective manner (Petersen 2021). (Source: Value in Health)
Source: Value in Health - January 1, 2022 Category: International Medicine & Public Health Authors: R Taylor, S Lad, E Petersen, T Stauss, J White, B Healey, M Baker-Wagner, N Sacks, S Patil, D Caraway, E Brooks Source Type: research
A Real-World Analysis of High-Frequency 10 kHz Spinal Cord Stimulation for the Treatment of Painful Diabetic Peripheral Neuropathy
CONCLUSIONS: This real-world study in typical clinical practices found 10 kHz SCS provided meaningful pain relief for a substantial proportion of patients refractory to current pDPN management, similar to published literature. This patient population has tremendous unmet needs and this study helps demonstrate the potential for 10 kHz SCS to provide an alternative pain management approach.PMID:34842489 | DOI:10.1177/19322968211060316 (Source: Pain Physician)
Source: Pain Physician - November 29, 2021 Category: Anesthesiology Authors: Jeffrey L Chen Andrew W Hesseltine Sara E Nashi Shawn M Sills Tory L McJunkin Sandeep Patil Manish Bharara David L Caraway Elizabeth S Brooks Source Type: research
Assessment of black cumin (Nigella sativa L.) as a food ingredient and putative therapeutic agent
Regul Toxicol Pharmacol. 2021 Nov 25:105088. doi: 10.1016/j.yrtph.2021.105088. Online ahead of print.ABSTRACTThe whole or ground seeds of the food ingredient Nigella sativa L., known in Western culture as "black cumin" or "black caraway", has a three-millennial history of use in Middle- and Far-Eastern cultures as a food ingredient. The seed and its extracts have also been increasingly reported as a successful therapeutic agent with efficacy often attributed to the presence of the powerful antioxidant, thymoquinone. However, quantitative analysis of the seed (especially the volatile fraction) yields widely variable results...
Source: Regulatory Toxicology and Pharmacology : RTP - November 28, 2021 Category: Toxicology Authors: George A Burdock Source Type: research
Assessment of black cumin (Nigella sativa L.) as a food ingredient and putative therapeutic agent
Regul Toxicol Pharmacol. 2021 Nov 25:105088. doi: 10.1016/j.yrtph.2021.105088. Online ahead of print.ABSTRACTThe whole or ground seeds of the food ingredient Nigella sativa L., known in Western culture as "black cumin" or "black caraway", has a three-millennial history of use in Middle- and Far-Eastern cultures as a food ingredient. The seed and its extracts have also been increasingly reported as a successful therapeutic agent with efficacy often attributed to the presence of the powerful antioxidant, thymoquinone. However, quantitative analysis of the seed (especially the volatile fraction) yields widely variable results...
Source: Regulatory Toxicology and Pharmacology : RTP - November 28, 2021 Category: Toxicology Authors: George A Burdock Source Type: research
