Cancers, Vol. 16, Pages 1611: An Overview of the Spices Used for the Prevention and Potential Treatment of Gastric Cancer
We present the potential molecular mechanisms responsible for the effectivity of a given seasoning substance and their impact on GC cells. We discuss their potential effects on proliferation, apoptosis, and migration. For most of the spices discussed, we also outline the unavailability and side effects of their use. (Source: Cancers)
Source: Cancers - April 22, 2024 Category: Cancer & Oncology Authors: Katarzyna Kostelecka Łukasz Bryliński Olga Komar Justyna Michalczyk Agata Mi łosz Jan Bi łogras Filip Woli ński Alicja Forma Jacek Baj Tags: Review Source Type: research

Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review
Z Gastroenterol. 2024 Apr 11. doi: 10.1055/a-2279-5045. Online ahead of print.ABSTRACTPhytotherapeutics are gaining influence in the treatment of gastroenterological diseases. Their popularity and growing evidence of efficacy contribute to their integration into medical guidelines. A systematic screening identified recommended phytotherapeutic approaches. Based on current scientific data, some recommendations for the use of phytotherapeutic agents are given. For irritable bowel syndrome the use of peppermint oil is "strongly recommended", especially for pain and flatulence. Other phytotherapeutics such as STW-5, Tibetan Pa...
Source: Zeitschrift fur Gastroenterologie - April 11, 2024 Category: Gastroenterology Authors: Sandra Utz Miriam Bittel Jost Langhorst Source Type: research

Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review
Z Gastroenterol. 2024 Apr 11. doi: 10.1055/a-2279-5045. Online ahead of print.ABSTRACTPhytotherapeutics are gaining influence in the treatment of gastroenterological diseases. Their popularity and growing evidence of efficacy contribute to their integration into medical guidelines. A systematic screening identified recommended phytotherapeutic approaches. Based on current scientific data, some recommendations for the use of phytotherapeutic agents are given. For irritable bowel syndrome the use of peppermint oil is "strongly recommended", especially for pain and flatulence. Other phytotherapeutics such as STW-5, Tibetan Pa...
Source: Zeitschrift fur Gastroenterologie - April 11, 2024 Category: Gastroenterology Authors: Sandra Utz Miriam Bittel Jost Langhorst Source Type: research

Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review
Z Gastroenterol. 2024 Apr 11. doi: 10.1055/a-2279-5045. Online ahead of print.ABSTRACTPhytotherapeutics are gaining influence in the treatment of gastroenterological diseases. Their popularity and growing evidence of efficacy contribute to their integration into medical guidelines. A systematic screening identified recommended phytotherapeutic approaches. Based on current scientific data, some recommendations for the use of phytotherapeutic agents are given. For irritable bowel syndrome the use of peppermint oil is "strongly recommended", especially for pain and flatulence. Other phytotherapeutics such as STW-5, Tibetan Pa...
Source: Zeitschrift fur Gastroenterologie - April 11, 2024 Category: Gastroenterology Authors: Sandra Utz Miriam Bittel Jost Langhorst Source Type: research

Exploring The Diverse Therapeutic Potentials of Synthetic Analogues of Keto-terpenoids (+) Carvone: A Future Scaffold
CONCLUSION: S(+) carvone has a CNS depressive impact and possesses an anti-convulsant activity. According to the research parameters on both the enantiomers, R&S can block GABA binding sites. Therefore, it suggests that S(+) carvone may be the new moiety for anticonvulsant activity. It has been observed by various studies that the S(+) carvone is more powerful than R(-) carvone. Therefore, it can be concluded that S(+) Carvone can serve as a scaffold for anticonvulsant activity.PMID:38551059 | DOI:10.2174/0118715249278766240322054108 (Source: Molecular Medicine)
Source: Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Snigdha Srivastava Reema Sinha Rahul Kaushik Rajan Kumar Kurmi Source Type: research

Exploring The Diverse Therapeutic Potentials of Synthetic Analogues of Keto-terpenoids (+) Carvone: A Future Scaffold
CONCLUSION: S(+) carvone has a CNS depressive impact and possesses an anti-convulsant activity. According to the research parameters on both the enantiomers, R&S can block GABA binding sites. Therefore, it suggests that S(+) carvone may be the new moiety for anticonvulsant activity. It has been observed by various studies that the S(+) carvone is more powerful than R(-) carvone. Therefore, it can be concluded that S(+) Carvone can serve as a scaffold for anticonvulsant activity.PMID:38551059 | DOI:10.2174/0118715249278766240322054108 (Source: Molecular Medicine)
Source: Molecular Medicine - March 29, 2024 Category: Molecular Biology Authors: Snigdha Srivastava Reema Sinha Rahul Kaushik Rajan Kumar Kurmi Source Type: research

Abstract No. 267 Treatment of Painful Diabetic Neuropathy: 10-kHz Spinal Cord Stimulation Provides Durable Pain Relief and Sensory Function Improvements
The objective of this study was to evaluate the long-term safety and effectiveness of high-frequency (10 kHz) spinal cord stimulation (SCS) for the treatment of painful diabetic neuropathy (PDN). (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - February 21, 2024 Category: Radiology Authors: E. Petersen, T. Stauss, J. Scowcroft, M. Jaasma, J. White, S. Sills, K. Amirdelfan, M. Guirguis, D. Beall, J. Dunleavy, C. Argoff, C. Nasr, R. Taylor, D. Caraway, N. Mekhail Source Type: research

Methyl Red Adsorption on Biochar Obtained by Physical Activation of Caraway Seeds with Carbon Dioxide
In this study carbon adsorbents were produced from caraway (Carum carvi L.) seeds, through direct and physical activation by carbon dioxide. The resulting biochar adsorbents were analyzed using low-temperature nitrogen adsorption-desorption isotherms and Boehm titration. Furthermore, the acid-base properties of the biochar samples obtained were examined, and the pH of their aqueous extracts was determined. The obtained adsorbents had a specific surface area ranging between 10 to 70 m2/g. Resulting carbon materials exhibited a predominance of basic groups on their surfaces. The sorption capacities of methyl red for the samp...
Source: Chemphyschem - January 5, 2024 Category: Chemistry Authors: Dorota Paluch Aleksandra Bazan-Wozniak Robert Pietrzak Source Type: research

Methyl Red Adsorption on Biochar Obtained by Physical Activation of Caraway Seeds with Carbon Dioxide
In this study carbon adsorbents were produced from caraway (Carum carvi L.) seeds, through direct and physical activation by carbon dioxide. The resulting biochar adsorbents were analyzed using low-temperature nitrogen adsorption-desorption isotherms and Boehm titration. Furthermore, the acid-base properties of the biochar samples obtained were examined, and the pH of their aqueous extracts was determined. The obtained adsorbents had a specific surface area ranging between 10 to 70 m2/g. Resulting carbon materials exhibited a predominance of basic groups on their surfaces. The sorption capacities of methyl red for the samp...
Source: Chemphyschem - January 5, 2024 Category: Chemistry Authors: Dorota Paluch Aleksandra Bazan-Wozniak Robert Pietrzak Source Type: research

Advances in Implant Technologies for Spine Surgery
Spine implants are becoming increasingly diversified. Taking inspiration from other industries, three-dimensional modeling of the spinal column has helped meet the custom needs of individual patients as both en bloc replacements and pedicle screw designs. Intraoperative tailoring of devices, a common need in the operating room, has led to expandable versions of cages and interbody spacers. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - November 24, 2023 Category: Neurosurgery Authors: Shahab Aldin Sattari, Yuanxuan Xia, Tej D. Azad, Chad A. Caraway, Louis Chang Source Type: research

Antibacterial efficacy of an ultra-short palmitoylated random peptide mixture in mouse models of infection by carbapenem-resistant < em > Klebsiella pneumoniae < /em >
Antimicrob Agents Chemother. 2023 Oct 11:e0057423. doi: 10.1128/aac.00574-23. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics has imposed a selective pressure for the rapid rise in bacterial resistance, creating an urgent need for novel therapeutics for managing bacterial infectious diseases while counteracting bacterial resistance. Carbapenem-resistant Klebsiella pneumoniae strains have become a major challenge in modern medicine due to their ability to cause an array of severe infections. Recently, we have shown that the 20-mer random peptide mixtures are effective therapeutics against three ESKAPEE patho...
Source: Antimicrobial Agents and Chemotherapy - October 11, 2023 Category: Microbiology Authors: Jonathan Z Lau Shanny Hsuan Kuo Yael Belo Einav Malach Bar Maron Hannah E Caraway Myung Whan Oh Yi Zhang Nahed Ismail Gee W Lau Zvi Hayouka Source Type: research

Antibacterial efficacy of an ultra-short palmitoylated random peptide mixture in mouse models of infection by carbapenem-resistant < em > Klebsiella pneumoniae < /em >
Antimicrob Agents Chemother. 2023 Oct 11:e0057423. doi: 10.1128/aac.00574-23. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics has imposed a selective pressure for the rapid rise in bacterial resistance, creating an urgent need for novel therapeutics for managing bacterial infectious diseases while counteracting bacterial resistance. Carbapenem-resistant Klebsiella pneumoniae strains have become a major challenge in modern medicine due to their ability to cause an array of severe infections. Recently, we have shown that the 20-mer random peptide mixtures are effective therapeutics against three ESKAPEE patho...
Source: Antimicrobial Agents and Chemotherapy - October 11, 2023 Category: Microbiology Authors: Jonathan Z Lau Shanny Hsuan Kuo Yael Belo Einav Malach Bar Maron Hannah E Caraway Myung Whan Oh Yi Zhang Nahed Ismail Gee W Lau Zvi Hayouka Source Type: research

Lower dose of plant substance more effective in repelling < em > Rhyzopertha dominica < /em > F . (Coleoptera, Bostrichidae) and < em > Sitophilus granarius < /em > L. (Coleoptera, Dryophthoridae)
CONCLUSIONS: The most interesting results were obtained concerning the relationship: the lower tested substance concentration caused a much stronger repellent effect of R. dominica and S. granarius..PMID:37772516 | DOI:10.26444/aaem/163326 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - September 29, 2023 Category: Environmental Health Authors: Aleksandra Maria Izdebska Ma łgorzata Kłyś Magdalena Nowak-Chmura Sylwia Koczanowicz Source Type: research

Lower dose of plant substance more effective in repelling < em > Rhyzopertha dominica < /em > F . (Coleoptera, Bostrichidae) and < em > Sitophilus granarius < /em > L. (Coleoptera, Dryophthoridae)
CONCLUSIONS: The most interesting results were obtained concerning the relationship: the lower tested substance concentration caused a much stronger repellent effect of R. dominica and S. granarius..PMID:37772516 | DOI:10.26444/aaem/163326 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - September 29, 2023 Category: Environmental Health Authors: Aleksandra Maria Izdebska Ma łgorzata Kłyś Magdalena Nowak-Chmura Sylwia Koczanowicz Source Type: research

Lower dose of plant substance more effective in repelling < em > Rhyzopertha dominica < /em > F . (Coleoptera, Bostrichidae) and < em > Sitophilus granarius < /em > L. (Coleoptera, Dryophthoridae)
CONCLUSIONS: The most interesting results were obtained concerning the relationship: the lower tested substance concentration caused a much stronger repellent effect of R. dominica and S. granarius..PMID:37772516 | DOI:10.26444/aaem/163326 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - September 29, 2023 Category: Environmental Health Authors: Aleksandra Maria Izdebska Ma łgorzata Kłyś Magdalena Nowak-Chmura Sylwia Koczanowicz Source Type: research