What Has A.I. In Medicine Ever Done For Us? At Least 50 Things!
Remember Monty Python’s brilliant Life of Brian movie scene where the Judean Jewish insurgent commando, planning the abduction of Pilate’s wife in return for all the horrors they had to endure from the Roman Empire, asks the rhetorical question: what have the Romans ever done for us? With the hype and overmarketing, not to speak about the fears around A.I, we asked the same question. What has A.I. in medicine ever done for us? Well, we found at least 50 things. I have 50 responses to the pressing question on everyone’s mind who is interested in healthcare but tired of the hype or the doomsday scenarios around A.I....
Source: The Medical Futurist - March 1, 2022 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine AI cancer diagnostics digital health Healthcare Innovation medical Radiology technology medical imaging treatment administration digital health technology Source Type: blogs

What the Pandemic Taught Us About Value-based Care
By RICHARD ISSACS You’ll recall that we ran a long piece (pt 1, pt 2) about Medicare Advantage from former Kaiser Permanente CEO George Halvorson earlier this year. Here’s a somewhat related piece from the current head of the Permanente Medical Group about what actually happened there and elsewhere during the pandemic–Matthew Holt The COVID-19 pandemic has provided important lessons regarding the structure and delivery of health care in the United States, and one of the most significant takeaways has been the need to shift to value-based models of care. The urgency for this transformation was cle...
Source: The Health Care Blog - February 17, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Physicians Kaiser Permanente Medicare Advantage Pandemic Richard Isaacs value-based care Source Type: blogs

Fight Aging! Newsletter, January 24th 2022
In conclusion, senolytic drugs have shown promising results in the elimination of senescent cells and in alleviating various diseases in animal models. However, in patients, there is a paucity in data on the efficacy and safety of senotherapeutics from clinical trials, including systemic effects and side-effects. In this regard it is important to assess the specificity of senolytics in killing targeted senescent cells and their cytotoxic effects, to identify reliable markers for intervention responses, to elucidate interactions with comorbidities and other drugs, and to standardise administration protocols. FOXO3...
Source: Fight Aging! - January 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Gameto Raises $20M at an Early Stage to Focus on Ovarian Aging
One of the signs of investor enthusiasm for an industry is the existence of projects that raise significant funding at a very early stage of their development. We're seeing that happen for cellular reprogramming, but companies started by well-connected individuals in other parts of the longevity industry are now raising a great deal of funding in early preclinical stages of development. This suggests that we will continue to see a growing influx of capital into the development of ways to treat aging as a medical condition, pulling more research projects out of the constraints of academia and into an environment of greater ...
Source: Fight Aging! - January 18, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Protein calorie malnutrition is devastating for patients [PODCAST]
“My practice consisted of patients who suffered from serious injuries and illnesses. Concerning the latter, a significant number had cancer, especially breast cancer. The issue all patient groups have in common to a certain degree is protein calorie malnutrition (PCM). The most dramatically affected are those stricken with a malignancy. PCM leads to increased morbidity,Read more …Protein calorie malnutrition is devastating for patients [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 23, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Surgery Source Type: blogs

Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Fasting Mimicking Diet Improves Anti-Cancer Immune Function
The fasting mimicking diet is, in essence, a clever strategy to pull in significant funding for the rigorous study of the use of forms of calorie restriction as a therapy. A fasting mimicking diet involves taking in just few enough calories to trigger most of the benefits of fasting. There must exist a dividing line in calorie intake at which nutrient sensor mechanisms determine that the body is in a state of fasting. Early research into fasting mimicking found that dividing line to be somewhere in the vicinity of 500 to 750 calories daily, but later studies use lower calorie levels. Another important point of calibration ...
Source: Fight Aging! - December 3, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

A physician and sister, but also an accomplice?
My older sister, Joy, will soon die from metastatic breast cancer.   She will pass away at age 50.  She will leave behind a husband of 21 years and the three children they nurtured to young adulthood.  Our elderly parents will lament the unnatural timing of their firstborn’s death.   And, I will mourn this loss, wondering whether my support ofRead more …A physician and sister, but also an accomplice? originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 1, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/kasi-chu" rel="tag" > Kasi Chu, MD < /a > < /span > Tags: Physician Oncology/Hematology Source Type: blogs

THCB Spotlights: Maya Said, CEO, Outcomes4Me
Today on THCB Spotlights, Matthew Holt talks with Maya Said, the CEO of Outcomes4Me, which works in the cancer patient empowerment space. Outcomes4Me is a patient empowerment platform that helps patients diagnosed or in active treatment for breast cancer understand their situation and treatment options, as well as connect better with providers to enable meaningful shared decision making. Maya tells us about the goals of Outcomes4Me, the current needs for enabling value-based care, and what the future directions are for Outcomes4Me, which recently received $16 million from North Point. (Source: The Health Care Blog)
Source: The Health Care Blog - November 23, 2021 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech THCB Spotlights Breast cancer Maya Said Outcomes4Me patient empowerment patient-centered outcomes value-based care Source Type: blogs

Fight Aging! Newsletter, November 15th 2021
This article will review the relationship between diabetes mellitus and AD as it relates to tau pathology. More understanding of the link between diabetes mellitus and AD could change the approach researchers and clinicians take toward both diseases, potentially leading to new treatments and preventative strategies in the future. Signaling from White Fat Tissue Contributes to Age-Related Hair Follicle Dysfunction https://www.fightaging.org/archives/2021/11/signaling-from-white-fat-tissue-contributes-to-age-related-hair-follicle-dysfunction/ Changes in fat tissue behavior in the skin take place with age,...
Source: Fight Aging! - November 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Daily Calorie Restriction is Better than Intermittent Fasting at Slowing Cancer in Mice
Restricting calorie intake stresses and kills cancer cells, for a variety of reasons both direct (cancer cells have high metabolic requirements) and indirect (calorie restriction improves immune function). Calorie restriction, a flat reduction in calorie intake, and intermittent application of fasting or fasting mimicking diets have been shown to improve outcomes in animal studies and human trials. Which of these options are better, however? Researchers here provide evidence to suggest that calorie restriction is better than a fasting mimicking diet when it comes to slowing cancer. Calorie restriction (CR) is with...
Source: Fight Aging! - November 8, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Tackling racial disparities in cancer care by creating new ways for institutions to operate
At 84, Emma Shuford found a lump in her breast. After a lumpectomy, she was diagnosed with locally aggressive breast cancer. Her doctors said it was treatable but she needed radiation to help stop it from growing. At first, she refused. Because of her age and a chronic leg injury, she didn ’t feel safe drivingRead more …Tackling racial disparities in cancer care by creating new ways for institutions to operate originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 31, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/joseph-d-stern" rel="tag" > Joseph D. Stern, MD, PhD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs

Protein calorie malnutrition is devastating for patients
I am a former chief of surgery and a scientific entrepreneur. My practice consisted of patients who suffered from serious injuries and illnesses.   Concerning the latter, a significant number had cancer, especially breast cancer.  The issue all patient groups have in common to a certain degree is protein calorie malnutrition (PCM).  The most dramatically affectedRead more …Protein calorie malnutrition is devastating for patients originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 26, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/steve-snodgrass" rel="tag" > Steve Snodgrass, MD < /a > < /span > Tags: Conditions Nutrition Surgery Source Type: blogs

Breast cancer ’s silver lining
In many ways, this woman was similar to other patients I have seen after a diagnosis and treatment of breast cancer. Her hair was growing back, and I immediately noticed that she was comfortable enough to not be wearing a wig or head covering for our Zoom visit. I keep my hair very short byRead more …Breast cancer’s silver lining originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 19, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/anne-katz" rel="tag" > Anne Katz, RN, PhD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs

Pink ribbons and murder boobs
I woke up this morning to a flood of ballerina pink emails for Breast Cancer Awareness Month. The irony was not lost on me as I rolled over in bed, protecting my body from the healing scars of where my breasts used to be. “I don’t even like pink,” I muttered to myself, while swallowingRead more …Pink ribbons and murder boobs originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 5, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/heather-e-schultz" rel="tag" > Heather E. Schultz, MD, MPH < /a > < /span > Tags: Physician Oncology/Hematology Source Type: blogs