FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients
Conditions: Brain Tumor, Primary; Exercise Interventions: Other: High-Intensity Interval Training (HIIT) Sponsors: Amsterdam UMC, location VUmc Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
Conditions: Glioblastoma, IDH-wildtype; Glioblastoma; Glioblastoma Multiforme of Brain; Astrocytoma, Malignant; Brain Neoplasms; Brain Neoplasms, Adult, Malignant; Brain Neoplasms, Adult; Recurrent Adult Brain Tumor; Recurrent Glioblastoma Interventions: Procedure: Awake mapping under local anesthesia; Procedure: Asleep mapping under general anesthesia; Procedure: Resection under general anesthesia without mapping Sponsors: Erasmus Medical Center; Haaglanden Medical Centre; Universitaire Ziekenhuizen KU Leuven; University Hospital Heidelberg; Technical University of Munich; Insel Gruppe AG, University Hospital Bern; Massac...
Source: ClinicalTrials.gov - February 22, 2024 Category: Research Source Type: clinical trials
Upright Open MRI for Brain Imaging in Children - a Pilot Study
Conditions: Brain Tumor Interventions: Procedure: MRI scan Sponsors: Nottingham University Hospitals NHS Trust Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials
Increasing Diagnosis Rates While Reducing Examination Time: Can MR Fingerprinting Deliver on Its Promise?
Conditions: Neurodevelopmental Disorders; Neurodegenerative Diseases; Brain Tumor; Multiple Sclerosis; Epilepsy Interventions: Diagnostic Test: MRI exam with Magnetic Resonance Fingerprinting Sponsors: IRCCS Fondazione Stella Maris; Azienda Ospedaliero, Universitaria Pisana Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials
Efficacy and Safety of T-DXd in HER2-mutant Advanced Lung Cancer Patients With Asymptomatic Brain Metastases
Conditions: Non Small Cell Lung Cancer Interventions: Drug: Trastuzumab deruxtecan Sponsors: Yonsei University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 9, 2024 Category: Research Source Type: clinical trials
Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases
Conditions: Non Small Cell Lung Cancer; NSCLC; KRAS G12C Interventions: Drug: Adagrasib; Radiation: Stereotactic Radiosurgery Sponsors: Ryan Gentzler, MD; Mirati Therapeutics Inc.; University of Virginia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials
MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer
Conditions: Breast Cancer Interventions: Diagnostic Test: Brain imaging; Diagnostic Test: Analysis of circulating tumor DNA; Behavioral: Testing Morbidities Index Sponsors: Sunnybrook Health Sciences Centre; Princess Margaret Hospital, Canada; MOUNT SINAI HOSPITAL; Trillium Health Partners Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials
Retrospective Study on the Prediction of Radiation-induced Brain Injury in Patients With Nasopharyngeal Carcinoma
Conditions: Nasopharyngeal Carcinoma; Radiation-Induced Temporal Lobe Injury Interventions: Radiation: intensity-modulated radiotherapy Sponsors: Jiangsu Cancer Institute& Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 6, 2024 Category: Research Source Type: clinical trials
Cancer Precision-Prevention trial of Metformin in adults with Li Fraumeni syndrome (MILI) undergoing yearly MRI surveillance: a randomised controlled trial protocol
DiscussionAlongside a parallel MILI study being conducted by collaborators at the National Cancer Institute (NCI), MILI is the first prevention trial to be conducted in this high-risk group. The MILI study provides a unique opportunity to evaluate the efficacy of metformin as a chemopreventive alongside exploring its m echanism of anticancer action and the biological process of mutated P53-driven tumourigenesis.Trial registrationISRCTN16699730. Registered on 28 November 2022. URL:https://www.isrctn.com/ EudraCT/CTIS number 2022-000165-41. (Source: Trials)
Source: Trials - February 3, 2024 Category: Research Source Type: clinical trials
Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
Conditions: Breast Cancer; Triple Negative Breast Cancer Interventions: Radiation: Stereotactic Radiation; Drug: Zimberelimab; Drug: Sacituzumab govitecan Sponsors: H. Lee Moffitt Cancer Center and Research Institute; Gilead Sciences Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 2, 2024 Category: Research Source Type: clinical trials
Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.
Conditions: Non-small Cell Lung Cancer; Brain Metastases; EGFR Gene Mutation Interventions: Combination Product: Nitroglycerin Sponsors: Instituto Nacional de Cancerologia de Mexico Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 2, 2024 Category: Research Source Type: clinical trials
The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In Craniotomies
Conditions: Brain Tumor; Bleeding Interventions: Drug: TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION; Other: Placebo Sponsors: Stephen Lownie; Dalhousie University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 29, 2024 Category: Research Source Type: clinical trials
Integrated PET/MRI and Germline Variants to Differentiate Brain Tumopr Recurrence From Iatrogenicchanges in Children
Conditions: Pediatric Brain Tumor Interventions: Diagnostic Test: 11C-MET-PET/RMN Sponsors: IRCCS San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 26, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG
Conditions: DIPG Brain Tumor; Diffuse Intrinsic Pontine Glioma Interventions: Biological: B7H3 specific CAR T cell with IL-7Ra signaling domain Sponsors: Chulalongkorn University; King Chulalongkorn Memorial Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials
Evaluation of a Mindfulness Intervention to Prevent Chemo-brain in Women Preparing for Chemotherapy for Breast Cancer
Conditions: Breast Carcinoma Interventions: Behavioral: Mindfulness Relaxation; Procedure: Functional Magnetic Resonance Imaging; Procedure: Biospecimen Collection; Other: Questionnaire Administration Sponsors: Thomas Jefferson University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials
