Next Generation Chemistry Centers for Fusion Oncoproteins (UM1 Clinical Trial Not Allowed)
Funding Opportunity RFA-CA-23-037 from the NIH Guide for Grants and Contracts. NCI is forming the Targeting Fusion Oncoproteins in Childhood Cancers (TFCC) Network to advance our understanding of the mechanisms of action of fusion oncoproteins in pediatric cancers and to apply novel chemical strategies for developing targeted therapeutic approaches. This RFA will use the UM1 mechanism to fund Next Generation Chemistry Centers (NGC) for Fusion Oncoproteins that have independent research projects using innovative chemical biology technologies and chemoproteomic approaches to target fusion-driven cancers. The goal of these...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 17, 2023 Category: Research Source Type: funding

Mechanisms of Fusion-Driven Oncogenesis in Childhood Cancers (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-CA-23-036 from the NIH Guide for Grants and Contracts. NCI is forming the Targeting Fusion Oncoproteins in Childhood Cancers (TFCC) Network to advance our understanding of the mechanisms of action of fusion oncoproteins in pediatric cancers and to apply novel chemical strategies for developing targeted therapeutic approaches. This RFA will use the U01 mechanism to solicit applications focused on molecular mechanisms by which fusion oncoproteins drive pediatric cancers with the goals of better understanding the biology of these cancers and identifying potential drug targets or critical dependencie...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 17, 2023 Category: Research Source Type: funding

Pediatric Immunotherapy Network (PIN) (U01 Clinical Trial Optional)
Funding Opportunity RFA-CA-22-016 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) intends to solicit applications for the Pediatric Immunotherapy Network (PIN). The overall goal of this FOA is to establish a collaborative network consisting of investigators with relevant expertise to develop and advance novel translational immunotherapy approaches for children and adolescents with solid tumors including brain tumors. This FOA solicits U01 applications for discrete research projects that address relevant research opportunities focused o...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 5, 2022 Category: Research Source Type: funding

Limited Competition: Pediatric Brain Tumor Consortium (UM1 Clinical Trials Required)
Funding Opportunity RFA-CA-19-059 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is intended to continue support for the Pediatric Brain Tumor Consortium (PBTC). This Limited-Competition FOA solicits a single application from the current PBTC awardee. The PBTC was conceived as a dedicated clinical trials organization able to translate innovative therapies from the laboratory to early phase clinical testing so that treatment for primary brain tumors in children can be improved. The importance of the PBTC is highlighted by the continuing high mortality rate among some common brain...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 23, 2019 Category: Research Source Type: funding

NIH Annual Snapshot – FY 2018 By the Numbers
We recently released our annual web reports and success rate data with updated numbers for fiscal year (FY) 2018. These web products represent annual snapshots of NIH research investments, which are highlighted in this post. Before delving into the numbers, we want to draw your attention to the new and modernized NIH Data Book recently released. This easy to navigate tool enables users to access and interact with a wealth of data ranging from NIH funding, research grant types, success rates, and much more (see this NIH Open Mike post for more). Now, let’s look at the numbers.  In FY 2018, NIH’s budget incre...
Source: NIH Extramural Nexus - March 13, 2019 Category: Research Authors: Mike Lauer Tags: blog Open Mike FY 2018 Success Rate Source Type: funding

Microbial-based Cancer Therapy -Bugs as Drugs (R21 Clinical Trial Not Allowed)
Funding Opportunity PAR-19-194 from the NIH Guide for Grants and Contracts. The overall purpose of this funding opportunity announcement (FOA) is to stimulate the development of novel microbial-based cancer therapies, especially for conditions where conventional cancer therapies are inadequate, such as poorly vascularized, hypoxic, solid tumors, dormant or slowly dividing cells resistant to current interventions, and brain tumors. Utilizing bacteria, archaebacteria, bacteriophages and other non-virus microorganisms, this initiative will support research projects designed to study the underlying mechanisms of the complex...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2019 Category: Research Source Type: funding

Microbial-based Cancer Therapy -Bugs as Drugs (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-19-193 from the NIH Guide for Grants and Contracts. The overall purpose of this funding opportunity announcement (FOA) is to stimulate the development of novel microbial-based cancer therapies, especially for conditions where conventional cancer therapies are inadequate, such as poorly vascularized, hypoxic, solid tumors, dormant or slowly dividing cells resistant to current interventions, and brain tumors. Utilizing bacteria, archaebacteria, bacteriophages and other non-virus microorganisms, this initiative will support research projects designed to study the underlying mechanisms of the complex...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2019 Category: Research Source Type: funding

Biophotonics
Funding Opportunity ID: 291989 Opportunity Number: PD-17-7236 Opportunity Title: BiophotonicsOpportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: GrantCategory of Funding Activity: Science and Technology and other Research and DevelopmentCategory Explanation: CFDA Number(s): 47.041Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Additional Information on Eligibility: Agency Code: NSFAgency Name: National Science FoundationPosted Date: Feb 22, ...
Source: Grants.gov - February 22, 2017 Category: Research Tags: Science and Technology and other Research and Development Source Type: funding

Administrative Supplements to Promote Research Collaborations on Fusion Oncoproteins as Drivers of Childhood Cancer (Admin Supp)
Funding Opportunity ID: 291452 Opportunity Number: PA-17-138 Opportunity Title: Administrative Supplements to Promote Research Collaborations on Fusion Oncoproteins as Drivers of Childhood Cancer (Admin Supp)Opportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: GrantCategory of Funding Activity: EducationHealthCategory Explanation: CFDA Number(s): 93.396Eligible Applicants: State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American...
Source: Grants.gov - February 19, 2017 Category: Research Tags: Education Health Source Type: funding

Administrative Supplements to Promote Research Collaborations on Fusion Oncoproteins as Drivers of Childhood Cancer (Admin Supp)
Funding Opportunity PA-17-138 from the NIH Guide for Grants and Contracts. This Administrative Supplement funding opportunity announcement is part of the Cancer Moonshot initiative to accelerate cancer research, and was developed in response to a recommendation from the Blue Ribbon Panel of experts charged with advising the National Cancer Advisory Board on the exceptional scientific opportunities that could be accelerated through this initiative. Based on the recommendation to intensify research and form highly dynamic and collaborative networks of investigators to advance our understanding of fusion oncoproteins as dr...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 26, 2017 Category: Research Source Type: funding

The 21st Century Cures Act, and Perspectives from NIH
You may have been following news of the 21st Century Cures Act, a landmark piece of legislation with provisions for healthcare, medicine, and research. Republican and Democratic lawmakers supported this bill through its development and eventual passage, and yesterday, President Obama signed the bill into law. The Act establishes a multitude of important changes to our nation’s approach to supporting and funding health care, medical interventions, and research. Readers of this blog may be particularly interested in the many changes directly relevant to NIH’s mission. A New England Journal of Medicine Perspective essay b...
Source: NIH Extramural Nexus - December 14, 2016 Category: Research Authors: Mike Lauer Tags: blog Open Mike 21st Century Cures Act General Source Type: funding

Biophotonics
Funding Opportunity ID: 287189 Opportunity Number: PD-16-7236 Opportunity Title: BiophotonicsOpportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: GrantCategory of Funding Activity: Science and Technology and other Research and DevelopmentCategory Explanation: CFDA Number(s): 47.041Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Additional Information on Eligibility: Agency Code: NSFAgency Name: National Science FoundationPosted Date: Aug 09, ...
Source: Grants.gov - August 9, 2016 Category: Research Tags: Science and Technology and other Research and Development Source Type: funding

DoD Gulf War Illness Epidemiology Research Award
Funding Opportunity Number: W81XWH-16-GWIRP-GWIERA Opportunity Category: DiscretionaryFunding Instrument Type: Cooperative AgreementGrantCategory of Funding Activity: Science and Technology and other Research and DevelopmentCFDA Number: 12.420Eligible Applicants Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Agency Name: DOD-AMRAAClosing Date: Oct 20, 2016Award Ceiling: $0Expected Number of Awards: 1Creation Date: May 13, 2016Funding Opportunity Description: The Gulf War Illness Epide...
Source: Grants.gov - May 13, 2016 Category: Research Tags: Science and Technology and other Research and Development Source Type: funding

Biophotonics
Funding Opportunity Number: PD-15-7236 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: Science and Technology and other Research and DevelopmentCFDA Number: 47.041Eligible Applicants Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Agency Name: NSFClosing Date: Oct 20, 2015Award Ceiling: $600,000Expected Number of Awards: Creation Date: Jul 24, 2015Funding Opportunity Description: The goal of the Biophotonicsprogram is to explore the resear...
Source: Grants.gov - July 24, 2015 Category: Research Tags: Science and Technology and other Research and Development Source Type: funding