A randomized controlled trial testing a hyaluronic acid spacer injection for skin toxicity reduction of brachytherapy accelerated partial breast irradiation (APBI): a study protocol
In this study, the effect of a subcutaneous spacer injection on the skin dose, late skin toxicity, and cosmetic outcome is tested in patients treated with PBSI in the setting of breast-conserving therapy. Our results will be relevant for most forms of breast brachytherapy as well as robotic radiosurgery, as skin spacers could protect the skin with these other techniques.Trial registrationNetherlands Trial Register,NTR6549. Registered on 27 June 2017. (Source: Trials)
Source: Trials - December 17, 2018 Category: Research Source Type: clinical trials

Contribution of Hypnosis to Anxiety and Pain in Brachytherapy Patients
Condition:   Brachytherapy Interventions:   Other: formal hypnosis;   Drug: Kalinox Sponsor:   Institut de Cancérologie de Lorraine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2018 Category: Research Source Type: clinical trials

Vaginal Elasticity Assessment Before and After Brachytherapy/Pelvic Radiation
Condition:   Radiation Injuries Intervention:   Diagnostic Test: Vaginal Tactile Imaging Sponsor:   Rambam Health Care Campus Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 12, 2018 Category: Research Source Type: clinical trials

MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer
Conditions:   Human Papillomavirus-Related Carcinoma;   Human Papillomavirus-Related Cervical Carcinoma;   Stage IB2 Cervical Cancer AJCC v8;   Stage II Cervical Cancer AJCC v8;   Stage II Vaginal Cancer AJCC v8;   Stage IIA Cervical Cancer AJCC v8;   Stage IIA Vaginal Cancer  AJCC v8;   Stage IIA1 Cervical Cancer AJCC v8;   Stage IIA2 Cervical Cancer AJCC v8;   Stage IIB&...
Source: ClinicalTrials.gov - August 16, 2018 Category: Research Source Type: clinical trials

Combined pretreatment with 18 F-FDG PET/CT and Comet assay guides the concurrent chemoradiotherapy of locally advanced cervical cancer: study protocol for a randomized controlled trial
DiscussionRapidArc has an obvious advantage in improving the degree of target coverage, improving organs at risk, sparing healthy tissue, and significantly reducing the treatment time. FDG-PET/CT can increase the agreement between biopsies and delineated tumor volume and has the potential to positively impact the course of treatment. The Comet assay is attractive as a potential clinical test of tumor radiosensitivity. During radiotherapy, accurately defining disease areas is critical to avoid the unnecessary irradiation of normal tissue. Based on FDG-PET/CT and Comet assay, higher doses can be safely delivered to accurate ...
Source: Trials - August 3, 2018 Category: Research Source Type: clinical trials

QuiremSpheres Observational Study
Conditions:   Hepatocellular Carcinoma;   Hepatocellular Carcinoma Non-resectable Intervention:   Device: Selective Internal Radiation Therapy with QuiremSpheres® Sponsor:   Terumo Europe N.V. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 20, 2018 Category: Research Source Type: clinical trials