Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy
Conditions:   Prostate Cancer;   Prostate Disease Interventions:   Drug: Nivolumab;   Radiation: Brachytherapy;   Radiation: External Beam Radiation Therapy;   Drug: Androgen Deprivation Therapy Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   Bristol-Myers Squibb Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 1, 2018 Category: Research Source Type: clinical trials

Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery
Conditions:   High-risk Prostate Cancer;   Prostate Cancer Interventions:   Drug: HSV-Tk;   Drug: Valacyclovir;   Drug: Bicalutamide;   Drug: Leuprolide Acetate;   Radiation: Brachytherapy, External beam radiotherapy;   Procedure: Radical prostatectomy Sponsor:   The Methodist Hospital System Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 31, 2018 Category: Research Source Type: clinical trials

Stereotactic body-radiotherapy boost dose of 18 Gy vs 21 Gy in combination with androgen-deprivation therapy and whole-pelvic radiotherapy for intermediate- or high-risk prostate cancer: a study protocol for a randomized controlled, pilot trial
DiscussionThe aim of this trial is to evaluate acute toxicities using both physician- and patient-reported outcomes and short-term biochemical control with SBRT boost following WPRT. Additionally, chronic toxicities and long-term biochemical control will be evaluated as secondary endpoints in this trial. Based on the generated results, we will plan the full-scale phase II study for selecting the SBRT boost dose.Trial registrationClinicalTrials.gov, ID;NCT03322020. Retrospectively registered on 26 October 2017. (Source: Trials)
Source: Trials - April 2, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
Conditions:   Endometrial Cancer Stage I;   Endometrial Cancer Stage II Interventions:   Radiation: Vaginal brachytherapy;   Radiation: External beam radiotherapy;   Other: Observation Sponsor:   Leiden University Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials

Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Conditions:   Neoplasms;   Cervical Adenosquamous Cell Carcinoma;   Cervical Squamous Cell Carcinoma in Situ;   Stage IB Cervical Cancer;   Stage IIA Cervical Cancer;   Stage IIB Cervical Cancer;   Stage III Cervical Cancer;   Stage IVA Cervical Cancer Interventions:   Drug: Nimotuzumab;   Drug: Cisplatin;   Radiation: external-beam radiation;   Radiation: brachytherapy Sponsor:   Zhujiang Hospital Not yet recruiting...
Source: ClinicalTrials.gov - March 19, 2018 Category: Research Source Type: clinical trials