Combined pretreatment with 18 F-FDG PET/CT and Comet assay guides the concurrent chemoradiotherapy of locally advanced cervical cancer: study protocol for a randomized controlled trial
DiscussionRapidArc has an obvious advantage in improving the degree of target coverage, improving organs at risk, sparing healthy tissue, and significantly reducing the treatment time. FDG-PET/CT can increase the agreement between biopsies and delineated tumor volume and has the potential to positively impact the course of treatment. The Comet assay is attractive as a potential clinical test of tumor radiosensitivity. During radiotherapy, accurately defining disease areas is critical to avoid the unnecessary irradiation of normal tissue. Based on FDG-PET/CT and Comet assay, higher doses can be safely delivered to accurate ...
Source: Trials - August 3, 2018 Category: Research Source Type: clinical trials

QuiremSpheres Observational Study
Conditions:   Hepatocellular Carcinoma;   Hepatocellular Carcinoma Non-resectable Intervention:   Device: Selective Internal Radiation Therapy with QuiremSpheres® Sponsor:   Terumo Europe N.V. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 20, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Condition:   Prostate Cancer - Recurrent Intervention:   Radiation: HDR Brachytherapy + EBRT + STAD Sponsor:   Loyola University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Conditions:   Prostate Adenocarcinoma;   Radiotherapy; Complications;   Tomotherapy Intervention:   Radiation: tomotherapy Sponsor:   Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2018 Category: Research Source Type: clinical trials

Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy
Conditions:   Prostate Cancer;   Prostate Disease Interventions:   Drug: Nivolumab;   Radiation: Brachytherapy;   Radiation: External Beam Radiation Therapy;   Drug: Androgen Deprivation Therapy Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   Bristol-Myers Squibb Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 1, 2018 Category: Research Source Type: clinical trials