Cancers, Vol. 13, Pages 1856: Radiotherapy for Clinically Localized T3b or T4 Very-High-Risk Prostate Cancer-Role of Dose Escalation Using High-Dose-Rate Brachytherapy Boost or High Dose Intensity Modulated Radiotherapy
a Haruumi Okabe To examine the efficacy of dose escalating radiotherapy into patients with cT3b or T4 localized prostate cancer, we compared Group A (86 conventional dose external beam radiotherapy: EBRT group, treated with 70–72Gy) and group B (39 high dose EBRT group (HDEBRT group, 74–80 Gy) and 124 high-dose-rate brachytherapy (HDR) + EBRT (HDR boost)) using multi-institutional retrospective data. The actuarial 5-year biochemical disease-free survival (bDFS) rate, prostate cancer specific survival rate (PSS), and overall survival rate (OS) were 75.8%, 96.8%, and 93.5%. Group B showed superior 5-year bD...
Source: Cancers - April 13, 2021 Category: Cancer & Oncology Authors: Hideya Yamazaki Gen Suzuki Koji Masui Norihiro Aibe Daisuke Shimizu Takuya Kimoto Ken Yoshida Satoaki Nakamura Haruumi Okabe Tags: Article Source Type: research

Radioactive and normal stent insertion for the treatment of malignant airway stenosis: A meta-analysis
To demonstrate the advantage of radioactive stent (RS) for treating malignant airway stenosis (MAS) in reducing the stent restenosis rate and increasing overall survival (OS). (Source: Brachytherapy)
Source: Brachytherapy - April 13, 2021 Category: Cancer & Oncology Authors: Qing-Kun Meng, Xiao-Ying Yu, Wei Li, Qing-Lan Sun Tags: Review Article Source Type: research

Current concepts on diffuse choroidal hemangioma in Sturge Weber syndrome
Conclusions: Multimodal ophthalmological imaging facilitates diagnosis of DCH and lifelong surveillance is essential in patients.PMID:33843430 | DOI:10.1080/13816810.2021.1910963 (Source: Ophthalmic Genetics)
Source: Ophthalmic Genetics - April 12, 2021 Category: Opthalmology Authors: Martina Formisano Maria Chiara di Pippo Luca Scuderi Solmaz Abdolrahimzadeh Source Type: research

Evaluation of camera settings for photogrammetric reconstruction of humanoid phantoms for EBRT bolus and HDR surface brachytherapy applications
In this study we investigate whether an alternative approach using photogrammetry techniques can improve this process and how camera settings and object texture affect the reconstructions. Two humanoid phantoms, an anthropomorphic RANDO phantom and a Laerdal Little Anne CPR training manikin were used in this study. Both were imaged using a Nikon D5600 DSLR and Nokia 3.1 smartphone camera and reconstructed using Agisoft Metashape software. CT scans of both phantoms were taken as references for comparing the photogrammetry reconstructions. Models were reconstructed from different photo sets and assessed by distance to agreem...
Source: Australasian Physical and Engineering Sciences in Medicine - April 12, 2021 Category: Biomedical Engineering Source Type: research

To 1000  Gy and back again: a systematic review on dose-response evaluation in selective internal radiation therapy for primary and secondary liver cancer
CONCLUSION: Although the existing evidence demonstrates a dose-response relationship in SIRT for both primary liver tumours and liver metastases, many pieces of the puzzle are still missing, hampering the definition of standardized dose thresholds. Nonetheless, most current evidence points towards a target mean dose of 100-250 Gy for HCC and 40-60 Gy for CRC. The field would greatly benefit from a reporting standard and prospective studies designed to elucidate the dose-response relation in different tumour types.PMID:33839892 | DOI:10.1007/s00259-021-05340-0 (Source: Molecular Medicine)
Source: Molecular Medicine - April 11, 2021 Category: Molecular Biology Authors: Joey Roosen Nienke J M Klaassen Lovisa E L Westlund Gotby Christiaan G Overduin Marcel Verheij Mark W Konijnenberg J Frank W Nijsen Source Type: research

To 1000  Gy and back again: a systematic review on dose-response evaluation in selective internal radiation therapy for primary and secondary liver cancer
ConclusionAlthough the existing evidence demonstrates a dose-response relationship in SIRT for both primary liver tumours and liver metastases, many pieces of the puzzle are still missing, hampering the definition of standardized dose thresholds. Nonetheless, most current evidence points towards a target mean dose of 100 –250 Gy for HCC and 40–60 Gy for CRC. The field would greatly benefit from a reporting standard and prospective studies designed to elucidate the dose-response relation in different tumour types. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 10, 2021 Category: Nuclear Medicine Source Type: research

Menstural function preservation treatment of a primary vaginal clear cell carcinoma with ovarian transposition and vaginal brachytherapy
Publication date: Available online 8 April 2021Source: Gynecologic Oncology ReportsAuthor(s): Dimitrios-Efthymios Vlachos, Athanasios Protopapas, Georgios Vlachos, Kyrillos Sarris, Maria Sotiropoulou, Maria Terzi, Dimitris Loutradis (Source: Gynecologic Oncology Reports)
Source: Gynecologic Oncology Reports - April 9, 2021 Category: OBGYN Source Type: research

Intracranial 131I-chTNT Brachytherapy in Patients with Deep-Seated Glioma: A Single-center Experience with 10-Year Follow-up from  China
CONCLUSION: 131I-chTNT intracranial brachytherapy is efficient and safe for patients with deep-seated glioma. It is a reliable option for inoperable glioma patients.PMID:33836553 | DOI:10.1055/a-1429-1967 (Source: Nuklearmedizin)
Source: Nuklearmedizin - April 9, 2021 Category: Radiology Authors: Ming Zhao Xiangping Fu Zhiwen Zhang Anmin Li Xiaopeng Wang Xuexiu Li Source Type: research

Intracranial 131I-chTNT Brachytherapy in Patients with Deep-Seated Glioma: A Single-center Experience with 10-Year Follow-up from  China
CONCLUSION: 131I-chTNT intracranial brachytherapy is efficient and safe for patients with deep-seated glioma. It is a reliable option for inoperable glioma patients.PMID:33836553 | DOI:10.1055/a-1429-1967 (Source: Nuklearmedizin)
Source: Nuklearmedizin - April 9, 2021 Category: Radiology Authors: Ming Zhao Xiangping Fu Zhiwen Zhang Anmin Li Xiaopeng Wang Xuexiu Li Source Type: research

Intracranial 131I-chTNT Brachytherapy in Patients with Deep-Seated Glioma: A Single-center Experience with 10-Year Follow-up from  China
CONCLUSION: 131I-chTNT intracranial brachytherapy is efficient and safe for patients with deep-seated glioma. It is a reliable option for inoperable glioma patients.PMID:33836553 | DOI:10.1055/a-1429-1967 (Source: Nuklearmedizin)
Source: Nuklearmedizin - April 9, 2021 Category: Radiology Authors: Ming Zhao Xiangping Fu Zhiwen Zhang Anmin Li Xiaopeng Wang Xuexiu Li Source Type: research

Analysis of a cohort of prostate patients treated with HDR mono-brachytherapy
AbstractThe aim of this study is to perform volumetric and basic radiobiological analyses using the database on prostate patients treated by HDR brachytherapy in our institution during the period 2011 –2016. Real-time ultrasound based technique was used, with Oncentra Prostate planning software. The whole period was divided into two sub-periods, according to the 100% dose per fraction, which was 10.5 Gy during the first period (2011–2012), and 11 Gy during the second period (2013–2016), f or each of the three fractions. The follow up time varied from 19 to 81 months, with a median of 45&nbs...
Source: Australasian Physical and Engineering Sciences in Medicine - April 9, 2021 Category: Biomedical Engineering Source Type: research

Intraoperative electron beam radiotherapy and perioperative high-dose-rate brachytherapy in previously irradiated oligorecurrent gynecological cancer: clinical outcome analysis
ConclusionsIOERT and PHDRB account for an effective salvage in  oligorecurrent gynecological tumors. Patients with previous pelvic radiation suitable for salvage surgery and at risk of inadequate margins could benefit from adjuvant reirradiation in form of IOERT or PHDRB. However, the rate of severe grade ≥ 3 toxicity associated with the entire treatment program is relevant and needs to be closely counterbalanced against the expected therapeutic gain. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - April 9, 2021 Category: Cancer & Oncology Source Type: research

Deep learning-based Auto-segmentation of Organs at Risk in High-Dose Rate Brachytherapy of Cervical Cancer
CONCLUSION: The proposed deep convolutional neural network model achieved a good agreement between the predicted and manually defined contours of OARs, thus improving the reproducibility of contouring in brachytherapy workflow.PMID:33831446 | DOI:10.1016/j.radonc.2021.03.030 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2021 Category: Radiology Authors: Reza Mohammadi Iman Shokatian Mohammad Salehi Hossein Arabi Isaac Shiri Habib Zaidi Source Type: research

Brachytherapy treatment verification using gamma radiation from the internal treatment source combined with an imaging panel - a phantom study
This study investigates the use of an imaging panel (IP) and the photons emitted by a high dose rate (HDR) 192Ir source to track source motion and obtain some information related to the patient anatomy. The feasibility of this approach was studied by monitoring the treatment delivery to a 3D printed phantom that mimicks a prostate patient. A 3D printed phantom was designed with a template for needle insertion, a cavity ("rectum") to insert an ultrasound probe, and lateral cavities used to place tissue-equivalent materials. CT images were acquired to create HDR 192Ir treatment plans with a range of dwell times, in...
Source: Physics in Medicine and Biology - April 8, 2021 Category: Physics Authors: Gabriel Paiva Fonseca Teun Pieter van Wagenberg Robert Voncken Mark Podesta Celine van Beveren Evert van Limbergen Ludy Lutgens Ben G L Vanneste Maaike Berbee Brigitte Reniers Frank Verhaegen Source Type: research

Deep learning-based Auto-segmentation of Organs at Risk in High-Dose Rate Brachytherapy of Cervical Cancer
CONCLUSION: The proposed deep convolutional neural network model achieved a good agreement between the predicted and manually defined contours of OARs, thus improving the reproducibility of contouring in brachytherapy workflow.PMID:33831446 | DOI:10.1016/j.radonc.2021.03.030 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2021 Category: Radiology Authors: Reza Mohammadi Iman Shokatian Mohammad Salehi Hossein Arabi Isaac Shiri Habib Zaidi Source Type: research

Brachytherapy treatment verification using gamma radiation from the internal treatment source combined with an imaging panel - a phantom study
This study investigates the use of an imaging panel (IP) and the photons emitted by a high dose rate (HDR) 192Ir source to track source motion and obtain some information related to the patient anatomy. The feasibility of this approach was studied by monitoring the treatment delivery to a 3D printed phantom that mimicks a prostate patient. A 3D printed phantom was designed with a template for needle insertion, a cavity ("rectum") to insert an ultrasound probe, and lateral cavities used to place tissue-equivalent materials. CT images were acquired to create HDR 192Ir treatment plans with a range of dwell times, in...
Source: Physics in Medicine and Biology - April 8, 2021 Category: Physics Authors: Gabriel Paiva Fonseca Teun Pieter van Wagenberg Robert Voncken Mark Podesta Celine van Beveren Evert van Limbergen Ludy Lutgens Ben G L Vanneste Maaike Berbee Brigitte Reniers Frank Verhaegen Source Type: research

Deep learning-based Auto-segmentation of Organs at Risk in High-Dose Rate Brachytherapy of Cervical Cancer
CONCLUSION: The proposed deep convolutional neural network model achieved a good agreement between the predicted and manually defined contours of OARs, thus improving the reproducibility of contouring in brachytherapy workflow.PMID:33831446 | DOI:10.1016/j.radonc.2021.03.030 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2021 Category: Radiology Authors: Reza Mohammadi Iman Shokatian Mohammad Salehi Hossein Arabi Isaac Shiri Habib Zaidi Source Type: research

Brachytherapy treatment verification using gamma radiation from the internal treatment source combined with an imaging panel - a phantom study
This study investigates the use of an imaging panel (IP) and the photons emitted by a high dose rate (HDR) 192Ir source to track source motion and obtain some information related to the patient anatomy. The feasibility of this approach was studied by monitoring the treatment delivery to a 3D printed phantom that mimicks a prostate patient. A 3D printed phantom was designed with a template for needle insertion, a cavity ("rectum") to insert an ultrasound probe, and lateral cavities used to place tissue-equivalent materials. CT images were acquired to create HDR 192Ir treatment plans with a range of dwell times, in...
Source: Physics in Medicine and Biology - April 8, 2021 Category: Physics Authors: Gabriel Paiva Fonseca Teun Pieter van Wagenberg Robert Voncken Mark Podesta Celine van Beveren Evert van Limbergen Ludy Lutgens Ben G L Vanneste Maaike Berbee Brigitte Reniers Frank Verhaegen Source Type: research

Brachytherapy treatment verification using gamma radiation from the internal treatment source combined with an imaging panel - a phantom study
This study investigates the use of an imaging panel (IP) and the photons emitted by a high dose rate (HDR) 192Ir source to track source motion and obtain some information related to the patient anatomy. The feasibility of this approach was studied by monitoring the treatment delivery to a 3D printed phantom that mimicks a prostate patient. A 3D printed phantom was designed with a template for needle insertion, a cavity ("rectum") to insert an ultrasound probe, and lateral cavities used to place tissue-equivalent materials. CT images were acquired to create HDR 192Ir treatment plans with a range of dwell times, in...
Source: Physics in Medicine and Biology - April 8, 2021 Category: Physics Authors: Gabriel Paiva Fonseca Teun Pieter van Wagenberg Robert Voncken Mark Podesta Celine van Beveren Evert van Limbergen Ludy Lutgens Ben G L Vanneste Maaike Berbee Brigitte Reniers Frank Verhaegen Source Type: research

IJERPH, Vol. 18, Pages 3932: Interventions Preventing Vaginitis, Vaginal Atrophy after Brachytherapy or Radiotherapy Due to Malignant Tumors of the Female Reproductive Organs —A Systematic Review
Conclusions: Vaginal suppositories were found to be clinically effective at the management of late-onset vulvovaginal side effects after radiotherapy. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - April 8, 2021 Category: Environmental Health Authors: Adrianna Wierzbicka Dorota Ma ńkowska-Wierzbicka Stanis ław Cieślewicz Marta Stelmach-Mardas Marcin Mardas Tags: Review Source Type: research

Live implant dosimetry may be an effective replacement for postimplant computed tomography in localized prostate cancer patients receiving low dose rate brachytherapy
To determine if Live Implant Dosimetry (LIDO) utilizing intraoperative transrectal ultrasound (TRUS) is equivalent to postimplant CT dosimetry (either day 0 or day 30) in patients with localized prostate cancer (PC) treated with low dose rate (LDR) prostate seed brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - April 8, 2021 Category: Cancer & Oncology Authors: Davood Roshan, Kieran Joyce, Peter Woulfe, Pradeep Reddy Gorakati, Richard Stock, Francis J. Sullivan Source Type: research

Quantifying risk using FMEA: An alternate approach to AAPM TG-100 for scoring failures and evaluating clinical workflow
Renovation of the brachytherapy program at a leading cancer center utilized methods of the AAPM TG-100 report to objectively evaluate current clinical brachytherapy workflows and develop techniques for minimizing the risk of failures, increasing efficiency, and consequently providing opportunities for improved treatment quality. The TG-100 report guides evaluation of clinical workflows with recommendations for identifying potential failure modes (FM) and scoring them from the perspective of their occurrence frequency O, failure severity S, and inability to detect them D. (Source: Brachytherapy)
Source: Brachytherapy - April 8, 2021 Category: Cancer & Oncology Authors: Sean A. Roles, Jaroslaw T. Hepel, Kara L. Leonard, David E. Wazer, Gene A. Cardarelli, Michelle L. Schwer, Ziad H. Saleh, Eric E. Klein, James M. Brindle, Mark J. Rivard Source Type: research

Patterns of definitive radiotherapy practice for cervical cancer in South Korea: a survey endorsed by the Korean Radiation Oncology Group (KROG 20-06)
CONCLUSION: Most differences were noted in the indications for treatment, RT field, and prescription dose. This finding can serve as a reference for establishing practical RT guidelines for the management of locally advanced cervical cancer.PMID:33825358 | DOI:10.3802/jgo.2021.32.e43 (Source: Journal of Gynecologic Oncology)
Source: Journal of Gynecologic Oncology - April 7, 2021 Category: OBGYN Authors: Nalee Kim Won Park Source Type: research

Bilateral ocular surface squamous neoplasia: A study of 25 patients and review of literature
CONCLUSION: OSSN occurrence can be synchronous or metachronous. Meticulous examination of the fellow eye is important for an early diagnosis of OSSN.PMID:33818167 | DOI:10.1177/11206721211007109 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 5, 2021 Category: Opthalmology Authors: Vijitha S Vempuluru Monalisha Pattnaik Neha Ghose Swathi Kaliki Source Type: research

Bilateral ocular surface squamous neoplasia: A study of 25 patients and review of literature
CONCLUSION: OSSN occurrence can be synchronous or metachronous. Meticulous examination of the fellow eye is important for an early diagnosis of OSSN.PMID:33818167 | DOI:10.1177/11206721211007109 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 5, 2021 Category: Opthalmology Authors: Vijitha S Vempuluru Monalisha Pattnaik Neha Ghose Swathi Kaliki Source Type: research

Bilateral ocular surface squamous neoplasia: A study of 25 patients and review of literature
CONCLUSION: OSSN occurrence can be synchronous or metachronous. Meticulous examination of the fellow eye is important for an early diagnosis of OSSN.PMID:33818167 | DOI:10.1177/11206721211007109 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - April 5, 2021 Category: Opthalmology Authors: Vijitha S Vempuluru Monalisha Pattnaik Neha Ghose Swathi Kaliki Source Type: research

APBI versus ultra APBI in the elderly with low-risk breast cancer: a comparative analysis of oncological outcome and late toxicity
Aim: Accelerated partial breast irradiation (APBI) represents a validated technique for low-risk breast cancer. Recently, ultra APBI (uAPBI) using fewer than 5 fractions were described in literature. We compared clinical outcome and late toxicity after APBI or uAPBI in the elderly.Material/methods: Two cohorts of elderly ( ≥ 70 years) low-risk breast cancer treated with APBI (interstitial brachytherapy) were retrospectively analyzed. A total dose of 34Gy/10f (APBI) or 16Gy/1f (uAPBI) was delivered from 2004 to 2012 and from 2013 to 2018 respectively. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - April 5, 2021 Category: Radiology Authors: Jean-Michel Hannoun-L évi, Lucile Montagne, Shakeel Sumodhee, Renaud Schiappa, Rabia Boulahssass, Mathieu Gautier, Jocelyn Gal, Marie-Eve Chand Source Type: research

Deep learning-based Auto-segmentation of Organs at Risk in High-Dose Rate Brachytherapy of Cervical Cancer
Delineation of organs at risk (OARs), such as the bladder, rectum and sigmoid, plays an important role in the delivery of optimal absorbed dose to the target owing to the steep gradient in high-dose rate brachytherapy (HDR-BT). In this work, we propose a deep convolutional neural network-based approach for fast and reproducible auto-contouring of OARs in HDR-BT. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - April 5, 2021 Category: Radiology Authors: Reza Mohammadi, Iman Shokatian, Mohammad Salehi, Hossein Arabi, Isaac Shiri, Habib Zaidi Tags: Original Article Source Type: research

ACR –ABS–ACNM–ASTRO–SIR–SNMMI practice parameter for selective internal radiation therapy or radioembolization for treatment of liver malignancies
The American College of Radiology (ACR), American Brachytherapy Society (ABS), American College of Nuclear Medicine (ACNM), American Society for Radiation Oncology (ASTRO), Society of Interventional Radiology (SIR), and Society of Nuclear Medicine and Molecular Imaging (SNMMI) have jointly developed a practice parameter on selective internal radiation therapy (SIRT) or radioembolization for treatment of liver malignancies. Radioembolization is the embolization of the hepatic arterial supply of hepatic primary tumors or metastases with a microsphere yttrium-90 brachytherapy device. (Source: Brachytherapy)
Source: Brachytherapy - April 3, 2021 Category: Cancer & Oncology Authors: Kelvin Hong, Olaguoke Akinwande, Lisa Bodei, Murthy RK. Chamarthy, Phillip M. Devlin, Shana Elman, Suvranu Ganguli, Andrew S. Kennedy, Sonya J. Koo, Zoubir Ouhib, Siddharth A. Padia, Riad Salem, Reed G. Selwyn, Catheryn M. Yashar, Don C. Yoo, Bassem I. Za Source Type: research

Virtual reality-based simulation improves gynecologic brachytherapy proficiency, engagement, and trainee self-confidence
Intracavitary brachytherapy is critical in treatment of cervical cancer with the highest rates of local control and survival. Only about 50% of graduating residents express confidence to develop a brachytherapy practice with caseload as the greatest barrier. We hypothesize that virtual reality (VR)-based intracavitary brachytherapy simulation will improve resident confidence, engagement, and proficiency. (Source: Brachytherapy)
Source: Brachytherapy - April 3, 2021 Category: Cancer & Oncology Authors: Neil K. Taunk, Nishant K. Shah, Emily Hubley, Shibu Anamalayil, Jacob W. Trotter, Taoran Li Source Type: research

Assessing the Relative Biological Effectiveness of High-dose Rate 60Co Brachytherapy Alone and in Combination with Cisplatin Treatment on a Cervical Cancer Cell Line (HeLa)
Publication date: Available online 30 March 2021Source: Radiation Physics and ChemistryAuthor(s): Shima Gharavian, Niloufar Hosseini Giv, Laleh Rafat Motavalli, Ahmad Reza Bahrami, Sara Abdollahi, Hashem Miri-Hakimabad, Maryam M. Matin (Source: Radiation Physics and Chemistry)
Source: Radiation Physics and Chemistry - March 31, 2021 Category: Physics Source Type: research

Radiation therapy for uveal melanoma: a review of treatment methods available in 2021
Purpose of review Radiation therapy has become the standard of care for the treatment of uveal melanoma. We intend to outline the current radiation therapy methods that are employed to treat uveal melanoma. We will outline their relative benefits over one another. We will also provide some background about radiation therapy in general to accustom the ophthalmologists likely reading this review. Recent findings Four main options exist for radiation therapy of uveal melanoma. Because the eye is a small space, and because melanomas are relatively radioresistant, oncologists treating uveal melanoma must deliver high...
Source: Current Opinion in Ophthalmology - March 31, 2021 Category: Opthalmology Tags: RETINAL, VITREOUS AND MACULAR DISORDERS: Edited by Brandon G. Busbee and John W. Kitchens Source Type: research

Vitreous seeding of choroidal melanoma
Conclusion: Vitreous seeding of choroidal melanoma poses a diagnostic and management challenge. (Source: RETINA)
Source: RETINA - March 31, 2021 Category: Opthalmology Tags: Clinicopathologic Correlation Source Type: research

Dosimetric comparison of volumetric modulated arc therapy (VMAT) and high-dose-rate brachytherapy (HDR-BT) for superficial skin irradiation with significant curvature in one or more planes
This study compares the plan quality of high-dose-rate brachytherapy (HDR-BT) and volumetric modulated arc therapy (VMAT) for superficial irradiation of large areas of skin with significant curvature in one or more planes.MethodsA total of 14 patients from two centres previously treated with either HDR-BT or VMAT were retrospectively replanned using the alternative technique. Sites included scalp and lower limbs. Identical computed tomography (CT) scans, clinical target volume (CTV) and organs at risk (OARs) and prescription were used for both techniques. Conformity, skin surface dose and OAR doses were compared.ResultsCon...
Source: Strahlentherapie und Onkologie - March 31, 2021 Category: Cancer & Oncology Source Type: research

Patient-reported Quality of Life After SBRT, LDR, and HDR Brachytherapy for Prostate Cancer: A Comparison of Outcomes
Conclusions: In a cohort of patients treated with modern radiotherapy techniques, HDR and SBRT resulted in clinically meaningful improved urinary PRQOL compared with LDR. (Source: American Journal of Clinical Oncology)
Source: American Journal of Clinical Oncology - March 30, 2021 Category: Cancer & Oncology Tags: Original Articles: Genitourinary Source Type: research

Localized and Locally Advanced Prostate Cancer: Treatment Options
Background: There are many treatment options for localized and locally advanced prostate cancer with radiotherapy and surgery representing the main local therapeutic strategies.Summary: Depending on the risk of disease recurrence, we can stratify patients into low-, intermediate- and high-risk groups, which will guide patients ’ treatment. For low-risk patients, active surveillance is an option. Brachytherapy is also an option for low- and intermediate-risk patients and can be used as a boost following external beam radiotherapy for high-risk patients. For intermediate- and high-risk patients, radical prostatectomy a...
Source: Oncology - March 30, 2021 Category: Cancer & Oncology Source Type: research

Localized and Locally Advanced Prostate Cancer: Treatment Options
Oncology. 2021 Mar 30:1-9. doi: 10.1159/000513258. Online ahead of print.ABSTRACTBACKGROUND: There are many treatment options for localized and locally advanced prostate cancer with radiotherapy and surgery representing the main local therapeutic strategies.SUMMARY: Depending on the risk of disease recurrence, we can stratify patients into low-, intermediate- and high-risk groups, which will guide patients' treatment. For low-risk patients, active surveillance is an option. Brachytherapy is also an option for low- and intermediate-risk patients and can be used as a boost following external beam radiotherapy for high-risk p...
Source: Oncology - March 30, 2021 Category: Cancer & Oncology Authors: V érane Achard C édric Michael Panje Daniel Engeler Thomas Zilli Paul Martin Putora Source Type: research

Localized and Locally Advanced Prostate Cancer: Treatment Options
Oncology. 2021 Mar 30:1-9. doi: 10.1159/000513258. Online ahead of print.ABSTRACTBACKGROUND: There are many treatment options for localized and locally advanced prostate cancer with radiotherapy and surgery representing the main local therapeutic strategies.SUMMARY: Depending on the risk of disease recurrence, we can stratify patients into low-, intermediate- and high-risk groups, which will guide patients' treatment. For low-risk patients, active surveillance is an option. Brachytherapy is also an option for low- and intermediate-risk patients and can be used as a boost following external beam radiotherapy for high-risk p...
Source: Oncology - March 30, 2021 Category: Cancer & Oncology Authors: V érane Achard C édric Michael Panje Daniel Engeler Thomas Zilli Paul Martin Putora Source Type: research

Five-year results of accelerated partial breast irradiation: A single-institution retrospective review of 289 cases
We report 5-year survival outcomes, cosmesis, and treatment-related toxicity. (Source: Brachytherapy)
Source: Brachytherapy - March 30, 2021 Category: Cancer & Oncology Authors: Maria Laplana, Salvatore Cozzi, Dina Najjari, Marta Irene Mart ín, Gerard Rodríguez, Andrea Slocker, Ismael Sancho, Maria Jesús Pla, Marc García, Ruth Gracia, Joan Pera, Ferran Guedea, Cristina Gutiérrez Source Type: research

Intraoperative optimization of seed implantation plan in breast brachytherapy
ConclusionThe proposed method can find the optimal implantation scheme corresponding to the current desired seed locations immediately once there is a change of patient ’s posture. This work can be applied to the robot-assisted LDR-PS breast brachytherapy for improving the operation accuracy and efficiency. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - March 29, 2021 Category: Intensive Care Source Type: research

Interstitial brachytherapy for gynecologic malignancies: Complications, toxicities, and management
From both a disease and management perspective, locally advanced gynecologic cancers present a significant challenge. Dose escalation with brachytherapy serves as a key treatment, providing conformal radiation while sparing at-risk organs. Intracavitary brachytherapy techniques have been shown to be effective, with improving tumor control and toxicity profiles with the advent of three-dimensional image planning. Despite this, the variations in tumor size, location, and pelvic anatomy may lead to suboptimal dosimetry with standard intracavitary applicators in some clinical scenarios. (Source: Brachytherapy)
Source: Brachytherapy - March 29, 2021 Category: Cancer & Oncology Authors: Mitchell Kamrava, Saad Maili Alrashidi, Eric Leung Source Type: research

Treatment Outcome and Prognosis Factors of FIGO 2018 Stage III Cervical Cancer Patients Treated with Definitive Concurrent Chemoradiation in Vietnam
CONCLUSIONS: 3D CRT and HDR brachytherapy with concurrent chemotherapy is an effective treatment, with acceptable toxicity for FIGO 2018 stage III cervical cancer in Vietnam..PMID:33773550 | DOI:10.31557/APJCP.2021.22.3.853 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2021 Category: Cancer & Oncology Authors: Huyen Thi Phung Minh Cong Truong Long Thanh Nguyen Anh Thi Van Dang Thanh Ha Vu Hoa Thi Nguyen Source Type: research