Immunohistochemical expression of PRAME in 485 cases of epithelial tubo-ovarian tumors
We examined 485 cases of epithelial tubo-ovarian tumors including 107 clear cell carcinomas (CCC), 52 endometroid carcinomas (EC), 103 high grade serous carcinomas (HGSC), 119 low grade serous carcinomas (LGSC)/micropapillary variant of serous borderline tumors (mSBT), and 104 cases of mucinous carcinomas (MC)/mucinous borderline tumors (MBT). The immunohistochemical analysis was performed using TMAs.The highest levels of expression were seen in EC (60%), HGSC (62%), and CCC (56%), while expression in LGSC/mSBT (4%) and MC/MBT (2%) was rare. The clinico-pathologic correlations and survival analysis showed no prognostic sig...
Source: Virchows Archiv - August 23, 2023 Category: Pathology Source Type: research

Molecular Status of < em > BRAF < /em > Mutation in Epithelial Ovarian Cancer: An Analysis of 57 Cases in the Northeast of Iran
CONCLUSION: The BRAF mutation is most frequent in borderline tumors but not in invasive serous carcinomas. It seems that 2 different pathways exist for the development of ovarian epithelial neoplasms: one for borderline tumors and the other for high-grade invasive carcinomas. Our study supports this hypothesis. The BRAF mutation is rare in mucinous neoplasms.PMID:37600581 | PMC:PMC10439751 | DOI:10.30699/IJP.2023.554750.2907 (Source: Cancer Control)
Source: Cancer Control - August 21, 2023 Category: Cancer & Oncology Authors: Amirhossein Jafarian Masoumeh Jafaripour Masoumeh Gharib Maryam Salehi Nema Mohamadian Roshan Sare Etemad Khatoone Mirshekar Maryam Sheikhi Masoumeh Heidari Behnaz Ahmadian Zahra Khoshnegah Hossein Ayatollahi Payam Siyadat Source Type: research

Serous surface papillary borderline ovarian tumors: sonographic features with clinicopathological correlation
This article is protected by copyright. All rights reserved.PMID:37592848 | DOI:10.1002/uog.27454 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - August 18, 2023 Category: Radiology Authors: D Wang N Su R Wang L Zhang Z Qi Z Liu J Yang J Leng Y Xiang Collaborators Source Type: research

Serous surface papillary borderline ovarian tumors: sonographic features with clinicopathological correlation
This article is protected by copyright. All rights reserved.PMID:37592848 | DOI:10.1002/uog.27454 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - August 18, 2023 Category: Radiology Authors: D Wang N Su R Wang L Zhang Z Qi Z Liu J Yang J Leng Y Xiang Collaborators Source Type: research

Serous surface papillary borderline ovarian tumors: sonographic features with clinicopathological correlation
This article is protected by copyright. All rights reserved.PMID:37592848 | DOI:10.1002/uog.27454 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - August 18, 2023 Category: Radiology Authors: D Wang N Su R Wang L Zhang Z Qi Z Liu J Yang J Leng Y Xiang Collaborators Source Type: research

Serous surface papillary borderline ovarian tumors: sonographic features with clinicopathological correlation
This article is protected by copyright. All rights reserved.PMID:37592848 | DOI:10.1002/uog.27454 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - August 18, 2023 Category: Radiology Authors: D Wang N Su R Wang L Zhang Z Qi Z Liu J Yang J Leng Y Xiang Collaborators Source Type: research

Ovarian serous borderline tumors with recurrent or extraovarian lesions: a Japanese, retrospective, multi-institutional, population-based study
ConclusionThe recurrence rate was lower in this cohort than previous reports, but the clinical impacts of incomplete resection and misclassification of the tumor were still significant on the treatment of SBT. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - August 1, 2023 Category: Cancer & Oncology Source Type: research

KRAS mutation in primary ovarian serous borderline tumors correlates with tumor recurrence
In conclusion,KRAS mutation in primary ovarian SBTs is significantly associated with a worse disease-free survival, independent of the high tumor stage or histological subtypes of extraovarian implant. KRAS mutation testing of primary ovarian SBT may servce as a useful biomarker for tumor recurrence. (Source: Virchows Archiv)
Source: Virchows Archiv - May 23, 2023 Category: Pathology Source Type: research

Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature
Z Geburtshilfe Neonatol. 2023 May 2. doi: 10.1055/a-2065-0231. Online ahead of print.ABSTRACTAdnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 2, 2023 Category: Perinatology & Neonatology Authors: Franziska Mergel Fabienne Schochter Nikolaus DeGregorio Wolfgang Janni Frank Reister Ulrike Friebe-Hofmann Beate H üner Source Type: research

Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature
Z Geburtshilfe Neonatol. 2023 May 2. doi: 10.1055/a-2065-0231. Online ahead of print.ABSTRACTAdnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 2, 2023 Category: Perinatology & Neonatology Authors: Franziska Mergel Fabienne Schochter Nikolaus DeGregorio Wolfgang Janni Frank Reister Ulrike Friebe-Hofmann Beate H üner Source Type: research

Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature
Z Geburtshilfe Neonatol. 2023 May 2. doi: 10.1055/a-2065-0231. Online ahead of print.ABSTRACTAdnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 2, 2023 Category: Perinatology & Neonatology Authors: Franziska Mergel Fabienne Schochter Nikolaus DeGregorio Wolfgang Janni Frank Reister Ulrike Friebe-Hofmann Beate H üner Source Type: research

Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature
Z Geburtshilfe Neonatol. 2023 May 2. doi: 10.1055/a-2065-0231. Online ahead of print.ABSTRACTAdnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 2, 2023 Category: Perinatology & Neonatology Authors: Franziska Mergel Fabienne Schochter Nikolaus DeGregorio Wolfgang Janni Frank Reister Ulrike Friebe-Hofmann Beate H üner Source Type: research

Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature
Z Geburtshilfe Neonatol. 2023 May 2. doi: 10.1055/a-2065-0231. Online ahead of print.ABSTRACTAdnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 2, 2023 Category: Perinatology & Neonatology Authors: Franziska Mergel Fabienne Schochter Nikolaus DeGregorio Wolfgang Janni Frank Reister Ulrike Friebe-Hofmann Beate H üner Source Type: research

Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature
Z Geburtshilfe Neonatol. 2023 May 2. doi: 10.1055/a-2065-0231. Online ahead of print.ABSTRACTAdnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of ...
Source: Zeitschrift fur Geburtshilfe und Neonatologie - May 2, 2023 Category: Perinatology & Neonatology Authors: Franziska Mergel Fabienne Schochter Nikolaus DeGregorio Wolfgang Janni Frank Reister Ulrike Friebe-Hofmann Beate H üner Source Type: research