MR-HIFU and ThermoDox to Treat Recurrent Childhood Tumors: Interview with AeRang Kim, Principal Investigator
Children’s National Health System and the Celsion Corporation (Lawrenceville, NJ) have recently announced a Phase I clinical trial in the US to determine a safe and tolerable dose of ThermoDox in conjunction with non-invasive magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU). The trial is aimed on young adults and children with recurring solid tumors.
ThermoDox technology consists of liposomes loaded with doxorubicin, a conventional chemotherapeutic drug. Liposomes are small lipid structures which can be used to encapsulate and deliver drugs through the bloodstream. While liposomal doxorubicin formu...
Source: Medgadget - December 6, 2016 Category: Medical Equipment Authors: Conn Hastings Tags: Exclusive Nanomedicine Oncology Source Type: blogs
Losing Friends
In conclusion, losing friends is a fact of life.
If you’ve lost a friend, try to examine why this occurred. Consider: are you better off without this “friend?” Mourn for a while; remember the good times. Finally, move on. Make a new friend or two.
You will survive. (Source: World of Psychology)
Source: World of Psychology - November 19, 2016 Category: Psychiatry & Psychology Authors: Laura Yeager Tags: Friends General Grief and Loss Self-Help Communication Dishonesty Envy Friendship Gossip Grudge Jealousy Making Friends Stigma Source Type: blogs
My 9/11 Shows That Cancer Patients Aren't Saints
I finally got a hold of my mom on the telephone on Sept. 11, 2001, just hours before I was supposed to receive my penultimate dose ofradiation to treat my bone cancer. After nearly a year of treatment, I only had two days left. My mom said the National Institutes of Health was closed and I couldn't get radiation that afternoon. The NIH would probably be closed the next day, too, my mom said. Instead of feeling sadness for my country and for the thousands of Americans who were injured or killed, I felt anger that I would have to wait to call myself "cancer-free."Cancer patients are often portrayed in the media and on televi...
Source: cancerslayerblog - September 12, 2016 Category: Cancer & Oncology Tags: fear and rage Source Type: blogs
A Scanning Approach to Detect Transthyretin Amyloid Buildup in the Heart
In this study, the researchers examined the diagnostic accuracy of the Tc 99m PYP test for ATTR-CA in a retrospective study of 179 amyloidosis patients (121 with ATTR and 50 with other types). The researchers found that the imaging test was able to correctly identify ATTR in 91 percent of those diagnosed with the disease, and was able to rule out ATTR-CA in 92 percent of those with other forms of amyloidosis or no amyloidosis.
Link: http://newsroom.cumc.columbia.edu/blog/2016/08/24/amyloid-related-heart-failure-now-detectable-with-imaging-test/ (Source: Fight Aging!)
Source: Fight Aging! - August 25, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Finding Pain Relief When There ’ s Potential for Addiction
I am a woman with a family history of addiction who is also in chronic pain. What if someday I need opioids to manage that pain?
First, two discs in my lower spine degenerated. Then, they herniated, both bulging out and impinging nerves, inciting an excruciating, sciatica-like pain that affected me around the clock. More than a year since my discs were damaged, pain has become my daily reality. I wake up stiff and sore as though I’ve just been hit by a car (having been hit by a car as a kid, I actually know what that feels like). The only thing I struggle with as much as the pain itself is finding the best way to treat i...
Source: World of Psychology - August 14, 2016 Category: Psychiatry & Psychology Authors: Psych Central Staff Tags: Addiction Health-related Personal Publishers The Fix Chronic Pain Drug Addiction drug counseling Epidemic Family History Laura Kiesel Medication Methadone opiods opioid addiction overdoses Pain Relief prescription drug ab Source Type: blogs
Fight Aging! Newsletter, July 25th 2016
This study builds on preliminary findings from the first phase of the INTERSTROKE study, which identified ten modifiable risk factors for stroke in 6,000 participants from 22 countries. The full-scale INTERSTROKE study included an additional 20,000 individuals from 32 countries in Europe, Asia, America, Africa and Australia, and sought to identify the main causes of stroke in diverse populations, young and old, men and women, and within subtypes of stroke.
To estimate the proportion of strokes caused by specific risk factors, the investigators calculated the population attributable risk for each factor (PAR; an esti...
Source: Fight Aging! - July 24, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Introducing Viral Cancer Therapies into the Spleen Greatly Improves Outcomes
There are plenty of results from the past decade to illustrate that the methodology by which a therapy is delivered makes a great deal of difference to the outcome in patients. Here, for example, researchers have found a way to improve the performance of viruses engineered to preferentially target cancer cells. We've been hearing less of this approach to cancer in the past few years, given the progress and more widespread support for cancer immunotherapy as a technology platform, but there are still many researchers working on the use of viruses in targeted cancer therapy, and a number of promising studies have resulted.
...
Source: Fight Aging! - July 19, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Matching Fund Donors Sought for SENS Universal Cancer Therapy Crowdfunding
There is a month left to go in the SENS crowdfunding campaign that aims to accelerate development of an important component of a universal cancer therapy, a way to block the mechanisms of telomere lengthening that every type of cancer depends upon. The SENS Research Foundation and Lifespan.io volunteers are looking for donors to put up matching funds of a few thousand dollars or more, in order to take that news and that inducement to a number of conferences and other events over the next few weeks. More than 150 people have donated to the campaign to date, and we'd like to triple that number in the next 30 days.
To ...
Source: Fight Aging! - July 18, 2016 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs
Fight Aging! Newsletter, June 20th 2016
We examined the engraftment and differentiation of alkaline phosphatase-positive NSCs expanded from the postnatal subventricular zone (SVZ), 3 months after grafting into the intact young or aged rat hippocampus. Graft-derived cells engrafted robustly into both young and aged hippocampi. Although most graft-derived cells pervasively migrated into different hippocampal layers, the graft cores endured and contained graft-derived neurons.
The results demonstrate that advanced age of the host at the time of grafting has no major adverse effects on engraftment, migration, and differentiation of grafted subventricular zone...
Source: Fight Aging! - June 19, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Crowdfunding Steps Towards a Universal Cancer Therapy: Help the SENS Research Foundation to Identify Drug Candidates and Mechanisms to Suppress ALT
The next stage in this year's SENS rejuvenation research funding initiatives launches today: the SENS Research Foundation is crowdfunding a search for drug candidates and mechanisms that can attack all ALT cancers, those that abuse the alternative lengthening of telomeres (ALT) processes to grow. This is a part of the OncoSENS program, which seeks to produce the grounding for a universal cancer treatment platform, based on the one commonality known to be shared by all cancers, which is that cancer cells must lengthen their telomeres, one way or another. You may recall coverage of the SENS Research Foundation ALT research i...
Source: Fight Aging! - June 15, 2016 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs
“For International Childhood Cancer Day, we’re sharing...
"For International Childhood Cancer Day, we're sharing this case of a 10-year-old boy with Ewing's Sarcoma who underwent limb salvage therapy. Here is the patient's femur. It was removed, treated with liquid nitrogen to kill remaining tumor cells, and then reimplanted. After surgery, recovery in the ICU, and chemotherapy, the patient is now able to ride his bike again. Thank you to all the healthcare professionals who treat and support children and adolescents with cancer like this every day." By figure1 on Instagram Posted on infosnack. (Source: Kidney Notes)
Source: Kidney Notes - February 15, 2016 Category: Urology & Nephrology Authors: Joshua Schwimmer Source Type: blogs
“For #WorldCancerDay, we’re sharing this case of a child...
"For #WorldCancerDay, we're sharing this case of a child diagnosed with a high-grade osteosarcoma of the left distal femur at age 13. After undergoing limb salvage surgery with implantation of a megaprosthesis plus pre- and post-operative chemotherapy, she is running again. More importantly, she has been cancer-free for two years now because of her care team. Thank you to all the healthcare professionals who support and treat cancer patients like her every day." By figure1 on Instagram Posted on infosnack. (Source: Kidney Notes)
Source: Kidney Notes - February 4, 2016 Category: Urology & Nephrology Authors: Joshua Schwimmer Source Type: blogs
Another child with cancer endangered by alternative medicine
Yesterday, I wrote about the winner of the Nobel Prize in Physiology or Medicine, Youyou Tu, who, after screening 2,000 herbal treatments from traditional Chinese medicine (TCM) for anti-malaria activity, finally discovered Artemisinin. She isolated it from the plant in which it is found, using modern chemistry to isolate it, purify it, and later chemically… (Source: Respectful Insolence)
Source: Respectful Insolence - October 8, 2015 Category: Surgery Authors: Orac Tags: Cancer Complementary and alternative medicine Politics Popular culture Quackery Science chemotherapy jaw law osteosarcoma surgery traditional Chinese medicine Source Type: blogs
When the back pain red flags aren’t enough
$28 million was awarded to a patient for a late diagnosis of a pelvic tumor, an osteosarcoma. This rare cancer presented as a case of low back pain and sciatica. The patient claimed that if the osteosarcoma had been caught earlier that the subsequent surgery would have been avoided.
Could doctors have done better in diagnosing more quickly?
These cases strike fear into all primary care doctors. Which patient has a sinister pathology when the majority of patients with similar symptoms of back pain are due to benign non-life threatening causes?
Continue reading ...
Your patients are rating you online: How to respond. Manage...
Source: Kevin, M.D. - Medical Weblog - April 19, 2015 Category: Journals (General) Authors: Davis Liu, MD Tags: Conditions Cancer Orthopedics Source Type: blogs
Preparation is Vital for a Good Cryopreservation
The cryonics industry provides the only alternative to the grave for people who will age to death prior to the advent of rejuvenation treatments. Sadly, even after four decades of service this remains a small industry and only a tiny fraction of those who die choose to take advantage of what is offered: low temperature preservation sufficient to maintain the fine structure of the brain until such time as the means for revival are created. Everyone else is gone to dust and oblivion, beyond any hope of returning. A number of people have put in a lot of time and effort to describing how the revival of cryopreserved individual...
Source: Fight Aging! - December 19, 2014 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
