Xdemvy < sup > TM < /sup > (Lotilaner Ophthalmic Solution) 0.25% Topical Solution for the Treatment of < em > Demodex < /em > Blepharitis
Skinmed. 2024 Mar 18;22(1):61-66. eCollection 2024.ABSTRACTXdemvyTM (lotilaner ophthalmic solution) 0.25% topical solution was recently approved for the treatment of Demodex blepharitis in adults aged ≥18 years. As an antiparasitic agent, lotilaner selectively inhibits gamma-aminobutyric acid chloride channels specific to the parasite and induces spastic paralysis, leading to death of Demodex blepharitis mites. In two randomized, double-masked, vehicle-controlled, multi-center, phase-3 clinical trials (Saturn-1 and Satuirn-2), lotilaner 0.25% topical solution was investigated for the treatment of Demodex blepharitis. Pat...
Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Aditya K Gupta Avantika Mann Kimberly Vincent William Abramovits Source Type: research
GSE230575 Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells
Conclusions: Taken together, we demonstrate that dupilumab effectively dampens conventional type 2 inflammation in DAHND lesions, with concomitant hyperactivation of _IL22_-associated responses. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - February 20, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Characteristics of bacterial community in eyelashes of patients with Demodex blepharitis
Demodex blepharitis (DB) is a common disease of the ocular surface. The characteristics of the bacterial community in eyelash roots after Demodex infestation are still unknown. Knowledge of the characteristics of... (Source: Parasites and Vectors)
Source: Parasites and Vectors - February 14, 2024 Category: Microbiology Authors: Dulei Zou, Xiuhai Lu, Fangying Song, Xiaowei Zhong, Huabo Chen, Ju Zhang, Yabin Tian, Li Pei, Fengjie Li, Xi Lu, Weiyun Shi and Ting Wang Tags: Research Source Type: research
Prevalence of common and rare ophthalmic findings in adults attending a medical survey institute
ConclusionsNormal ophthalmic data and the prevalences of ocular pathologies were extracted from a very large database of subjects seen at a single medical survey institute. (Source: International Ophthalmology)
Source: International Ophthalmology - February 9, 2024 Category: Opthalmology Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Efficacy and Safety of Lotilaner Ophthalmic Solution 0.25% in the Treatment of Demodex Blepharitis: A Systematic Review and Meta-Analysis
CONCLUSIONS: Our findings show that lotilaner might effectively treat Demodex blepharitis. However, further RCTs with larger and more diverse populations are needed to confirm these findings as some outcomes show significant heterogeneity.PMID:38301215 | DOI:10.1080/09273948.2024.2309552 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 1, 2024 Category: Allergy & Immunology Authors: Mohamed Abo Zeid Amr Elrosasy Ahmed W Abbas Asmaa Elganady Ahmed Elhadi Rhab Hashem Abu Serhan Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
Blepharitis in patients' eyelids: a discussion for nursing care
This article aims to create an awareness of this disease among community nurses by explaining its potential consequences to a person's physical and psychosocial wellbeing. Suggestions are made for its care and intervention.PMID:38300241 | DOI:10.12968/bjcn.2024.29.2.78 (Source: British Journal of Community Nursing)
Source: British Journal of Community Nursing - February 1, 2024 Category: Nursing Authors: Penelope Stanford Source Type: research
