Fight Aging! Newsletter, July 9th 2018
In this study, senescent cell distribution and quantity in vastus lateralis muscle were examined in young human adults after a single bout of resistance exercise. To determine the effects of dietary protein availability around exercise on senescent cell quantity and macrophage infiltration of skeletal muscle, two isocaloric protein supplements (14% and 44% in calorie) were ingested before and immediately after an acute bout of resistance exercise, in a counter-balanced crossover fashion. An additional parallel trial was conducted to compare the outcome of muscle mass increment under the same dietary conditions after 12 wee...
Source: Fight Aging! - July 8, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Biomedical Engineering in Medicine and Aging
Today, the effective treatment of aging can only proceed rapidly as an engineering project. The fine details of the way in which aging progresses at the level of cells and proteins are far from fully understood - but that is not a roadblock to progress. The research community knows enough of the causes of aging to repair them and observe the results. In fact the repair approach, where it has been tried, and as typified by senolytic development to clear senescent cells, is doing far more, with far less expenditure, and in far less time, than other strategies that involve mapping and adjusting the extreme complexity of cellu...
Source: Fight Aging! - July 6, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Scientists Identify Individuals from Brain Scans While Doing Tasks
All humans are unique individuals, some of it due to the differences between our brains. Being able to identify the differences in the structure and activity of our brains may have enormous consequences for neurology and neurosurgery.
While CT and MRI scans can’t yet provide a level of detail to diagnose many neurological conditions, researchers at Purdue University are working on using computational methods to spot biomarkers within imaging data. The team is relying on brain imaging scans obtained from the Human Connectome Project, a research venture to map the human brain. The scans were performed while the indiv...
Source: Medgadget - July 5, 2018 Category: Medical Devices Authors: Editors Tags: Informatics Neurology Radiology Source Type: blogs
Strained Guts: Engineering Human Intestinal Organoids for Transplantation
The increasing demand for organ transplantation has led many researchers to look for innovative ways to replace the need for human donors. Research in organoids, which are stem cell derived miniature mimics of organs typically grown in a dish, has significantly improved our understanding of organ development and structural organization. However, their size and simplicity has restricted organoid use to disease modeling and drug testing, limiting their potential for use in a transplantation setting. This is partly due to the fact that stem cells grown in a dish do not experience the same mechanical forces as they would in th...
Source: Medgadget - June 26, 2018 Category: Medical Devices Authors: Mohammad Saleh Tags: Genetics Materials Surgery Source Type: blogs
Wearable Vital Signs Monitor for Newborns: Interview with Neopenda Co-founders Sona Shah and Teresa Cauvel
Neopenda, a medical device startup based in Chicago, is developing medical solutions for low-resource settings, and has recently unveiled its first product, a wearable vital signs monitor for newborns. The company has reported that almost 3 million babies die within the first month of life. Up to 98% of these deaths occur in developing countries, and in many cases these deaths are preventable.
A lack of resources in many developing countries can result in understaffing and insufficient healthcare equipment. This can mean that it is difficult or impossible for healthcare staff to adequately monitor ill newborns to assess if...
Source: Medgadget - June 25, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Pediatrics Public Health Source Type: blogs
Is this Eye Tracking Device the Future of Brain Injury Diagnosis?
The common test for brain injury involves waving a finger back and forth in front of the patient ’s face, and seeing how well they can track it. Instead of relying on such antiquated protocols and standard imaging technology to identify brain injuries, two sisters have developed an eye-tracking device that can diagnose brain trauma.In 2013, Uzma Samadani, MD, PhD, neurosurgeon and associate professor of neurosurgery at the University of Minnesota and her sister Rosina Samadani, PhD, entrepreneur and biomedical engineer, started Oculogica, a neurodiagnostic company with a focus on eye-tracking devices. Specifically, their...
Source: radRounds - June 21, 2018 Category: Radiology Authors: Julie Morse Source Type: blogs
Device Delivers Drugs Direct to Heart to Help Recover from Heart Attacks
A team of researchers from the U.S. and Ireland have developed a device that can be used to deliver drugs directly to a damaged region of the heart. The capability has the potential to provide a direct therapeutic option to guide how the heart recovers following a heart attack, leading to improved cardiac function. As Ellen Roche, one of the authors of the paper appearing in Nature Biomedical Engineering, explains, “After a heart attack we could use this device to deliver therapy to prevent a patient from getting heart failure. If the patient already has some degree of heart failure, we can use the device to attenuate ...
Source: Medgadget - June 12, 2018 Category: Medical Devices Authors: Editors Tags: Cardiology Genetics Medicine Source Type: blogs
BMC enters the world of chemical engineering
As part of Springer Nature’s dedication to advancing discovery, BMC is expanding its scope beyond biology and medicine into the physical sciences and engineering. BMC Chemical Engineering is a new, open access, peer reviewed, community journal in chemical engineering. It launches alongside another engineering title BMC Biomedical Engineering, as Editor Alex Houssein explains in his blog, and ahead of a series of other new titles to come. Both chemical engineering and biomedical engineering are fields that combine engineering concepts with core scientific principles to develop real world solutions to the benefit of humani...
Source: BioMed Central Blog - June 12, 2018 Category: General Medicine Authors: Harriet Manning Tags: Open Access Publishing BMC Chemical Engineering BMC Series Source Type: blogs
BMC Biomedical Engineering: the BMC series expands into engineering!
I am delighted to announce that BMC Biomedical Engineering, a new open access, peer-reviewed journal is now open for submissions and with it the BMC series enters for the first time a new subject area: engineering. This is the first of two newly launched journals in the BMC series. Editor Harriet Manning discusses the launch of BMC Chemical Engineering in her blog post.
2018 has been declared as the “Year of Engineering” by the UK government, an initiative that has seen wide support by hundreds of national and international organisations. We see no better time to expand our offering to this diverse and crucial communit...
Source: BioMed Central Blog - June 12, 2018 Category: General Medicine Authors: Alexandros Houssein Tags: Medicine BMC Biomedical Engineering BMC Series Source Type: blogs
Sugar Nanoparticles Reprogram Immune Cells to Help Destroy Tumors
This report is in line with a number of recent papers from the Weissleder Lab and labs around the world to reprogram the immune system to fight cancer. Cancer immunotherapy was ranked the biggest breakthrough in 2012 by the magazine Science, and teams around the world are working on unlocking its potential to cure more patients of cancer. Tumor associated macrophages have been implicated in preventing T cells from doing their cancer-killing jobs, so these macrophage-targeting nanoparticles are poised solve the next hurdle in the immunotherapy story.
The cyclodextrin nanoparticles are formed by FDA-approved individual compo...
Source: Medgadget - June 11, 2018 Category: Medical Devices Authors: Ben Ouyang Tags: Nanomedicine Oncology Source Type: blogs
Computer Models of Arm and Hand Anatomy to Improve Function of Prosthetic Devices
New users of advanced prosthetic devices have to undergo tedious training routines in order for the computer that controls the given prosthesis to understand the wishes of the user. Sensors are used to measure the electrical activity of the muscles use to signal a prosthetic to move, but these signals change drastically depending on the user’s posture and orientation, amount of sweat formed between the skin and the sensors, and even the time of day.
Now researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a way of avoiding a lot of this training for pros...
Source: Medgadget - May 23, 2018 Category: Medical Devices Authors: Editors Tags: Rehab Source Type: blogs
3D-Printed Smart Gel Could Form Artificial Muscles
This study demonstrates how our 3D-printing technique can expand the design, size and versatility of this smart gel,” said Lee. “Our microscale 3D-printing technique allowed us to create unprecedented motions.”
See the gels in action in the following video:
Study in ACS Applied Materials & Interfaces: Soft Robotic Manipulation and Locomotion with a 3D Printed Electroactive Hydrogel…
Via: Rutgers University… (Source: Medgadget)
Source: Medgadget - May 22, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Materials Source Type: blogs
Topical Skin Lotion to Detect Variety of Disease Biomarkers
Scientists at the Nanyang Technological University in Singapore have developed a new way of utilizing nanotechnology to detect important biomarkers within the skin using what looks like a simple lotion.
Their NanoFlares, which are spherical, programmable nano-scale balls of nucleic acid, have gold cores. These NanoFlares are able to penetrate the skin and meet up with biochemicals within. When the nucleic acids interact with targeted biomarkers, the gold cores are exposed and the become free to fluoresce and therefore to be detected.
The researchers published their study in Nature Biomedical Engineering, but have also p...
Source: Medgadget - May 18, 2018 Category: Medical Devices Authors: Editors Tags: Dermatology Nanomedicine Source Type: blogs
