Mo1207 DEEP LEARNING AND HIGH-RESOLUTION ANOSCOPY: DEVELOPMENT OF AN INTEROPERABLE ARTIFICIAL INTELLIGENCE MODEL FOR THE DETECTION AND DIFFERENTIATION OF ANAL SQUAMOUS CELL CARCINOMA PRECURSORS – A MULTICENTRIC STUDY
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Miguel M. Saraiva, Lucas Spindler, Thiago Manzione, Nadia Fathallah, Tiago F. Ribeiro, Jo ão Afonso, Francisco Mendes, Miguel Martins, Pedro Cardoso, João Ferreira, Guilherme Macedo, Sidney R. Nadal, Vincent de Parades Tags: AGA Abstracts Source Type: research

Prevalence and incidence of anal high-grade squamous intraepithelial lesions in a cohort of cisgender men and transgender women who have sex with men diagnosed and treated during acute HIV acquisition in Bangkok, Thailand
CONCLUSIONS: With antiretroviral therapy initiation during acute HIV acquisition, we found the prevalence of anal HSIL among cisgender men and transgender women who have sex with men to be similar to those without HIV. Subsequent anal HSIL incidence, although lower than that of those with chronic HIV acquisition, was still higher than that of those without HIV. Screening for and management of anal HSIL should be a crucial part of long-term HIV care for all MSM.PMID:38695517 | DOI:10.1002/jia2.26242 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Supanat Thitipatarakorn Nipat Teeratakulpisarn Siriporn Nonenoy Aphakan Klinsukontakul Sujittra Suriwong Jirat Makphol Piranun Hongchookiat Thanyapat Chaya-Ananchot Napasawan Chinlaertworasiri Pravit Mingkwanrungruang Carlo Sacdalan Kultida Poltavee Tippa Source Type: research

Prevalence and incidence of anal high-grade squamous intraepithelial lesions in a cohort of cisgender men and transgender women who have sex with men diagnosed and treated during acute HIV acquisition in Bangkok, Thailand
CONCLUSIONS: With antiretroviral therapy initiation during acute HIV acquisition, we found the prevalence of anal HSIL among cisgender men and transgender women who have sex with men to be similar to those without HIV. Subsequent anal HSIL incidence, although lower than that of those with chronic HIV acquisition, was still higher than that of those without HIV. Screening for and management of anal HSIL should be a crucial part of long-term HIV care for all MSM.PMID:38695517 | PMC:PMC11064653 | DOI:10.1002/jia2.26242 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Supanat Thitipatarakorn Nipat Teeratakulpisarn Siriporn Nonenoy Aphakan Klinsukontakul Sujittra Suriwong Jirat Makphol Piranun Hongchookiat Thanyapat Chaya-Ananchot Napasawan Chinlaertworasiri Pravit Mingkwanrungruang Carlo Sacdalan Kultida Poltavee Tippa Source Type: research

Prevalence and incidence of anal high-grade squamous intraepithelial lesions in a cohort of cisgender men and transgender women who have sex with men diagnosed and treated during acute HIV acquisition in Bangkok, Thailand
CONCLUSIONS: With antiretroviral therapy initiation during acute HIV acquisition, we found the prevalence of anal HSIL among cisgender men and transgender women who have sex with men to be similar to those without HIV. Subsequent anal HSIL incidence, although lower than that of those with chronic HIV acquisition, was still higher than that of those without HIV. Screening for and management of anal HSIL should be a crucial part of long-term HIV care for all MSM.PMID:38695517 | DOI:10.1002/jia2.26242 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Supanat Thitipatarakorn Nipat Teeratakulpisarn Siriporn Nonenoy Aphakan Klinsukontakul Sujittra Suriwong Jirat Makphol Piranun Hongchookiat Thanyapat Chaya-Ananchot Napasawan Chinlaertworasiri Pravit Mingkwanrungruang Carlo Sacdalan Kultida Poltavee Tippa Source Type: research

Prevalence and incidence of anal high-grade squamous intraepithelial lesions in a cohort of cisgender men and transgender women who have sex with men diagnosed and treated during acute HIV acquisition in Bangkok, Thailand
CONCLUSIONS: With antiretroviral therapy initiation during acute HIV acquisition, we found the prevalence of anal HSIL among cisgender men and transgender women who have sex with men to be similar to those without HIV. Subsequent anal HSIL incidence, although lower than that of those with chronic HIV acquisition, was still higher than that of those without HIV. Screening for and management of anal HSIL should be a crucial part of long-term HIV care for all MSM.PMID:38695517 | PMC:PMC11064653 | DOI:10.1002/jia2.26242 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Supanat Thitipatarakorn Nipat Teeratakulpisarn Siriporn Nonenoy Aphakan Klinsukontakul Sujittra Suriwong Jirat Makphol Piranun Hongchookiat Thanyapat Chaya-Ananchot Napasawan Chinlaertworasiri Pravit Mingkwanrungruang Carlo Sacdalan Kultida Poltavee Tippa Source Type: research

The influence of home versus clinic anal human papillomavirus sampling on high-resolution anoscopy uptake in the Prevent Anal Cancer Self-Swab Study
We examined whether anal HPV sampling at home versus in a clinic impacts uptake of high-resolution anoscopy (HRA), an in-clinic procedure. Anal cytology history and insertive anal sex position were associated with higher HRA uptake, and attendance differed by race and HIV status in the clinic arm. Given that people living with HIV and Black men who have sex with men are disproportionately affected by anal cancer, interventions are needed to support their clinic attendance. (Source: Sexual Health)
Source: Sexual Health - April 29, 2024 Category: Sexual Medicine Authors: Jenna Nitkowski Timothy J. Ridolfi Sarah J. Lundeen Anna R. Giuliano Elizabeth Y. Chiao Maria E. Fernandez Vanessa Schick Jennifer S. Smith Bridgett Brzezinski Alan G. Nyitray Source Type: research

Condyloma and Anal Dysplasia
Surg Clin North Am. 2024 Jun;104(3):517-527. doi: 10.1016/j.suc.2023.11.004. Epub 2023 Dec 14.ABSTRACTAnal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoi...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Sarah M Haviland Mary T O'Donnell Source Type: research

Condyloma and Anal Dysplasia
Surg Clin North Am. 2024 Jun;104(3):517-527. doi: 10.1016/j.suc.2023.11.004. Epub 2023 Dec 14.ABSTRACTAnal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoi...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Sarah M Haviland Mary T O'Donnell Source Type: research

Condyloma and Anal Dysplasia
Surg Clin North Am. 2024 Jun;104(3):517-527. doi: 10.1016/j.suc.2023.11.004. Epub 2023 Dec 14.ABSTRACTAnal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoi...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Sarah M Haviland Mary T O'Donnell Source Type: research

Condyloma and Anal Dysplasia
Surg Clin North Am. 2024 Jun;104(3):517-527. doi: 10.1016/j.suc.2023.11.004. Epub 2023 Dec 14.ABSTRACTAnal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoi...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Sarah M Haviland Mary T O'Donnell Source Type: research

Condyloma and Anal Dysplasia
Surg Clin North Am. 2024 Jun;104(3):517-527. doi: 10.1016/j.suc.2023.11.004. Epub 2023 Dec 14.ABSTRACTAnal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoi...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Sarah M Haviland Mary T O'Donnell Source Type: research

Condyloma and Anal Dysplasia
Surg Clin North Am. 2024 Jun;104(3):517-527. doi: 10.1016/j.suc.2023.11.004. Epub 2023 Dec 14.ABSTRACTAnal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoi...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Sarah M Haviland Mary T O'Donnell Source Type: research

Condyloma and Anal Dysplasia
Surg Clin North Am. 2024 Jun;104(3):517-527. doi: 10.1016/j.suc.2023.11.004. Epub 2023 Dec 14.ABSTRACTAnal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoi...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Sarah M Haviland Mary T O'Donnell Source Type: research

Assessing the Potential of HPV16 E6 Seroprevalence as a Biomarker for Anal Dysplasia and Cancer Screening-A Systematic Review and Meta-Analysis
In conclusion, while HPV16 E6 seroprevalence demonstrates specificity as a potential biomarker for HPV-related AC, its utility as a standalone screening tool may be limited. Instead, it could serve effectively as a confirmation test, particularly in high-risk populations, alongside other diagnostic methods. Further research is imperative to explore HPV16 E6 seroconversion dynamics and alternative screening algorithms.PMID:38542409 | DOI:10.3390/ijms25063437 (Source: Anal Sci)
Source: Anal Sci - March 28, 2024 Category: Chemistry Authors: Sara Tous Mariona Guillamet Tim Waterboer Laia Alemany Sonia Paytubi Source Type: research

Assessing the Potential of HPV16 E6 Seroprevalence as a Biomarker for Anal Dysplasia and Cancer Screening-A Systematic Review and Meta-Analysis
In conclusion, while HPV16 E6 seroprevalence demonstrates specificity as a potential biomarker for HPV-related AC, its utility as a standalone screening tool may be limited. Instead, it could serve effectively as a confirmation test, particularly in high-risk populations, alongside other diagnostic methods. Further research is imperative to explore HPV16 E6 seroconversion dynamics and alternative screening algorithms.PMID:38542409 | DOI:10.3390/ijms25063437 (Source: Anal Sci)
Source: Anal Sci - March 28, 2024 Category: Chemistry Authors: Sara Tous Mariona Guillamet Tim Waterboer Laia Alemany Sonia Paytubi Source Type: research