Repairing the photosynthetic enzyme Rubisco
(Max-Planck-Gesellschaft) Researchers at the Max Planck Institute of Biochemistry decipher the molecular mechanism of Rubisco Activase (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 20, 2020 Category: Biology Source Type: news

Tenecteplase an Alternative to Alteplase for Stroke Thrombolysis During Pandemic Tenecteplase an Alternative to Alteplase for Stroke Thrombolysis During Pandemic
Tenecteplase can be useful as an alternative to alteplase for stroke thrombolysis during the COVID-19 pandemic, according to an opinion piece.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - July 22, 2020 Category: Intensive Care Tags: Cardiology News Source Type: news

Thrombectomy Alone Noninferior to Combination Therapy in Stroke Thrombectomy Alone Noninferior to Combination Therapy in Stroke
Although results of the DIRECT-MT trial did show noninferiority with the combination of thrombolysis and thrombectomy, they do not rule out a benefit of alteplase, researchers conclude.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 7, 2020 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Endovascular Thrombectomy Alone Noninferior in Ischemic Stroke
THURSDAY, May 7, 2020 -- Endovascular thrombectomy alone is noninferior to endovascular thrombectomy preceded by intravenous alteplase for patients with acute ischemic stroke from large-vessel occlusion, according to a study published online May 6... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 7, 2020 Category: Pharmaceuticals Source Type: news

Benefits of Switching to Tenecteplase for Stroke Thrombolysis Benefits of Switching to Tenecteplase for Stroke Thrombolysis
Switching from alteplase to tenecteplase as the routine thrombolytic in acute ischemic stroke is having multiple benefits for at least one US hospital system, researchers report.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - February 29, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Thrombolysis Effective for Treating Occluded Central Venous Catheters in Kids Thrombolysis Effective for Treating Occluded Central Venous Catheters in Kids
Thrombolysis, particularly with alteplase, appears to be effective and likely safe for treating occluded central venous catheters in children with cancer, according to a meta-analysis.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 10, 2019 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Widely available drug may reduce head injury deaths
Early treatment with tranexamic acid could save many lives Related items fromOnMedica Risk/benefit balance of alteplase shifts quickly Earlier thrombolysis improves stroke outcomes Alteplase use linked to reduction in disability after stroke Lengthen GP training to include dementia New guidance to prevent strokes (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 14, 2019 Category: UK Health Source Type: news

Genentech Issues Voluntary Nationwide Recall of Three Lots of Activase & reg; (Alteplase)-100 mg Due to Lack of Sterility Assurance of the Sterile Water for Injection
Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), is voluntarily recalling three lots of Activase ® (alteplase) 100mg vials, that were co-packaged with Sterile Water for Injection, to the hospital level. The vials of Sterile Water for Injection, manufactured by Hospira Inc., a Pfizer company, and packaged with Activase 100 mg, may be cracked or chipped at the neck of the vial and leaking. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 24, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Intrapleural alteplase and domase  alfa cost effective
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - May 31, 2019 Category: Drugs & Pharmacology Source Type: news

Nerve stimulation could provide new treatment option for most common type of stroke
Research led by a UCLA scientist found that a new nerve stimulation therapy to increase blood flow could help patients with the most common type of stroke up to 24 hours after onset.A study of 1,000 patients found evidence that the technique, called active nerve cell cluster stimulation, reduced the patients ’ degree of disability three months after they suffered an acute cortical ischemic stroke, which affects the surface of the brain.Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center, was the co-principal investigator of the study, which was conducted at 73 medical centers in 18 countries.“We believe ...
Source: UCLA Newsroom: Health Sciences - May 24, 2019 Category: Universities & Medical Training Source Type: news

Large trial says aspirin safe for brain bleed stroke patients
Study says brain haemorrhage survivors should continue taking antiplatelet medicines Related items fromOnMedica Treatment of hypertension for low-risk patients questioned Avoid BP-lowering drugs in stroke Adding insulin to metformin linked to higher mortality Stroke rate higher in HIV patients Risk/benefit balance of alteplase shifts quickly (Source: OnMedica Latest News)
Source: OnMedica Latest News - May 22, 2019 Category: UK Health Source Type: news

Alteplase Seems Beneficial at 4.5 to 9.0 Hours After Stroke
THURSDAY, May 9, 2019 -- The use of alteplase between 4.5 and 9.0 hours after stroke onset results in a higher number of patients with no or minor neurological deficits, according to a study published in the May 9 issue of the New England Journal of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 9, 2019 Category: Pharmaceuticals Source Type: news

Healing time for ankle fracture could be shorter
Three weeks in a cast may be just as good as six Related items fromOnMedica Criminal sanctions fail to curb illegal drug use Commission calls for mental health parity in Northern Ireland Low back pain often wrongly treated worldwide Frail elderly at greatest risk after trauma surgery Risk/benefit balance of alteplase shifts quickly (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 24, 2019 Category: UK Health Source Type: news

Fibrinolytic No Help for Microvascular Obstruction in PCI
(MedPage Today) -- Low-dose alteplase flops in T-TIME trial (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - January 9, 2019 Category: Cardiology Source Type: news

T-TIME: Low-dose Alteplase No Match for Microvascular Obstruction T-TIME: Low-dose Alteplase No Match for Microvascular Obstruction
Microvascular obstruction, perceived as the ' final frontier ' in ST-segment elevation MI, failed to yield to low-dose intracoronary alteplase.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news