ENCHANTED results challenge reduced alteplase dose in Asian stroke patients
A reduced dose of alteplase has failed to prove itself noninferior to the standard dose in a predominantly Asian population of patients with ischaemic stroke. (Source: MedWire News)
Source: MedWire News - May 10, 2016 Category: Consumer Health News Tags: Stroke Source Type: news

Seeking an alteplase alternative for stroke
Where is a biosimilar when you need one? A few weeks ago, I reported on an advisory committee of the Food and Drug Administration overwhelmingly recommending that the agency approve a biosimilar... (Source: Family Practice News)
Source: Family Practice News - March 8, 2016 Category: Primary Care Source Type: news

Seeking an alteplase alternative for stroke
Where is a biosimilar when you need one? A few weeks ago, I reported on an advisory committee of the Food and Drug Administration overwhelmingly recommending that the agency approve a biosimilar... (Source: Clinical Neurology News)
Source: Clinical Neurology News - March 8, 2016 Category: Neurology Source Type: news

VIDEO: A better way to treat large intraventricular hemorrhages
LOS ANGELES – For intraventricular hemorrhages of at least 20 mL, alteplase (Activase – Genentech) delivered directly into the clot by external ventricular drain almost doubles the odds of achieving... (Source: Family Practice News)
Source: Family Practice News - February 29, 2016 Category: Primary Care Source Type: news

VIDEO: A better way to treat large intraventricular hemorrhages
LOS ANGELES – For intraventricular hemorrhages of at least 20 mL, alteplase (Activase – Genentech) delivered directly into the clot by external ventricular drain almost doubles the odds of achieving... (Source: Clinical Neurology News)
Source: Clinical Neurology News - February 29, 2016 Category: Neurology Source Type: news

Clot-busting drug improves survival for deadly form of stroke
Stephen FellerLOS ANGELES, Feb. 18 (UPI) -- Clot-busting drug Alteplase, used for heart attacks and non-bleeding strokes, can reduce disability and mortality in patients with a type of bleeding stroke. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 18, 2016 Category: Consumer Health News Source Type: news

Medtronic touts Solitaire stent retriever meta-analysis
The Solitare stent retriever Medtronic (NYSE:MDT) acquired for $50 billion last year when it bought Covidien is safe and highly effective when combined with standard care using the thrombolysis drug alteplase, according to a meta-analysis of 4 previous trials of the device. The transcatheter Solitaire device uses a stent-like device to trap and retrieve a blood clot in the brain in cases of ischemic stroke. Researchers from the 4 trials – Swift Prime, Revascat, Extend-IA and Escape – pooled their data to examine the results from 787 patients, randomized to either thrombectomy with the Solitaire device (401) or stan...
Source: Mass Device - February 18, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Clinical Trials Neurological Vascular Medtronic Stroke Source Type: news

No extra benefit from task-orientated stroke rehabilitation programmes
Nor did increasing therapy time offer additional improvement in motor functionRelated items from OnMedicaLight therapy may improve stroke recoveryTime to rethink 4.5h window for alteplase after strokeStroke patients still not getting care they needStroke and other vascular disordersNHS stroke care getting better (Source: OnMedica Latest News)
Source: OnMedica Latest News - February 10, 2016 Category: UK Health Source Type: news

Stroke patients still not getting care they need
Care has improved in some respects but patients still miss key interventions and assessmentsRelated items from OnMedicaRate of cognitive decline increases for years after strokeEarlier thrombolysis improves stroke outcomesDementia and stroke funding remains too low, say expertsTime to rethink 4.5h window for alteplase after stroke Stroke rates rocket in younger men and women (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 2, 2015 Category: UK Health Source Type: news

Self-managing anticoagulants may cut risks after surgery
All-cause mortality lower in those who self-managed after surgery to fit mechanical valvesRelated items from OnMedicaExpert review backs clot busting drug as safeTime to rethink 4.5h window for alteplase after strokeNICE recommends more INR self-monitoringSelf-monitoring cuts warfarin clot riskExtending anticoagulation duration cuts risk of VTE recurrence (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 11, 2015 Category: UK Health Source Type: news

Lack of trial data may lead to wrong clinical choices
Data access should be mandatory, argue authorsRelated items from OnMedicaDoctors’ leaders consult on ethical use of dataDrug giant agrees to release all Tamiflu trial dataNICE rejects arguments against wider statin useUS doctor says FDA should have withdrawn rosuvastatinTime to rethink 4.5h window for alteplase after stroke (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 23, 2015 Category: UK Health Source Type: news

Blood thinners reduce angioplasty mortality
But only in certain groups do the benefits of GPI outweigh the increased risk of bleedingRelated items from OnMedicaHeart and stroke patients not getting best medicationEarlier thrombolysis improves stroke outcomesTime to rethink 4.5h window for alteplase after strokeExtending anticoagulation duration cuts risk of VTE recurrenceBeta blockers linked to higher surgical risks (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 20, 2015 Category: UK Health Source Type: news

Preventing carotid occlusion might not be reason for stenting
Preventive benefits of stenting in asymptomatic carotid stenosis no longer outweigh risks, study suggestsRelated items from OnMedicaFamily history doubles risk of aortic stenosisEarlier thrombolysis improves stroke outcomesTime to rethink 4.5h window for alteplase after strokeEndarterectomy cuts long-term stroke risk (Source: OnMedica Latest News)
Source: OnMedica Latest News - September 22, 2015 Category: UK Health Source Type: news

Expert review backs clot busting drug as safe
Review says alteplase is safe and effectiveRelated items from OnMedicaNew technology could determine use of thrombolysis post strokeUsers of HRT at risk of clots and strokeDementia and stroke funding remains too low, say expertsRate of cognitive decline increases for years after strokeTime to rethink 4.5h window for alteplase after stroke (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 24, 2015 Category: UK Health Source Type: news

Provisional green light for anti-clotting drug and quality standard for atrial fibrillation
Lixiana gets provisional thumbs up while new quality standard says that an AF score of two or more merits anticoagulant treatmentRelated items from OnMedicaNational VTE Prevention Programme helping to save livesGPs to review aspirin use in atrial fibrillation patientsImprove atrial fibrillation care to stave off 11,000 strokes every year, GPs toldTime to rethink 4.5h window for alteplase after strokeExtending anticoagulation duration cuts risk of VTE recurrence (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 13, 2015 Category: UK Health Source Type: news