Multi-drug resistant infections rising in children
(Rush University Medical Center) Antibiotic-resistant Acinetobacter baumannii infections, one of the most common hospital-acquired infections in children across the United States, are on the rise, according to results of a recent study published in the Journal of the Pediatric Infectious Diseases Society on March 22. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 11, 2018 Category: International Medicine & Public Health Source Type: news
Mixed progress on drug resistance in A. baumannii infections in children
(Center for Disease Dynamics, Economics& Policy) Researchers examined antibiotic resistance trends in clinical specimens from children with Acinetobacter baumannii infections, over 13 years. An overall increase was observed between 1999 and 2012 in the proportion of isolates that were resistant to cephalosporin and carbapenem; a slight decline was detected after a peak in 2008. 'It is encouraging to see a downtrend after 2008, but we need to continue to monitor resistance trends,' said study co-author Dr. Sumanth Gandra of CDDEP. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 2, 2018 Category: Infectious Diseases Source Type: news
Virulence switch in 'Iraqibacter': Potential Achilles heel?
(Emory Health Sciences) Microbiologists have identified a component of a genetic switch, which they call a potential 'Achilles' heel,' for a type of bacteria often associated with wounded warriors. The switch makes it possible for Acinetobacter baumannii to change between a virulent, hardy form and an avirulent form that is better at surviving at lower temperatures outside a host. Defining the switch could map out targets for new antibiotics. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 23, 2018 Category: Infectious Diseases Source Type: news
EARLY RELEASE: Increase in Hospital-Acquired Carbapenem-Resistant Acinetobacter baumannii Infection and Colonization in an Acute Care Hospital During a Surge in COVID-19 Admissions --- New Jersey, February--July 2020
This report describes a cluster of 34 carbapenem-resistant Acinetobacter baumannii cases in a New Jersey hospital that peaked during a surge in COVID-19 hospitalizations. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - April 17, 2018 Category: American Health Tags: Carbapenem Resistant Enterobacteriaceae (CRE) MMWR Morbidity & Mortality Weekly Report COVID-19 Coronavirus Disease 2019 Source Type: news
Research project on dangerous hospital germ extended
(Goethe University Frankfurt) Cases of multi-resistant bacteria in hospitals have increased dramatically in recent years and the health system faces tremendous problems as a result. Alongside 'old acquaintances', such as Staphylococcus aureus (MRSA) or Klebsiella pneumonia, another pathogen has now arrived on the scene: Acinetobacter baumannii. In order to find new weapons for the fight against this aggressive germ, in 2014 the German Research Foundation established a Research Unit led by Goethe University Frankfurt which has now been extended for a further three years. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 7, 2018 Category: International Medicine & Public Health Source Type: news
Coinfection with Acinetobacter baumannii Carbapenem-Resistant and Carbapenem-Susceptible Strains
Acinetobacter baumannii is an opportunistic pathogen that is emerging as an important cause of health care-associated infections, especially in patients in the intensive care unit (ICU) [1]. Among the carbapenem-hydrolyzing class D β-lactamases (CHDL), OXA-23-like enzymes are the most prevalent, occurring worldwide [2]. We isolated carbapenem-resistant and -susceptible A. baumannii strains from different sites in the same patient. Here, we describe the characterization of these isolates and discuss the implications of these f indings and their clinical importance. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - December 27, 2017 Category: Microbiology Authors: Karyne Rangel, Daniela Betzler, Cardoso Gomes, Gabrielle Limeira Genteluci, Maria Jos é de Souza, Maria Helena Simões Villas Bôas Tags: Case Report Source Type: news
Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa in health care facilities
The World Health Organization has produced these first global guidelines for preventing and controlling three types of carbapenem-resistant gram-negative bacteria in health settings. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 7, 2017 Category: Consumer Health News Source Type: news
Combined resistance to multiple antibiotics: A growing problem in the EU
(European Centre for Disease Prevention and Control (ECDC)) On the occasion of the 10th European Antibiotic Awareness Day, the European Centre for Disease Prevention and Control (ECDC) is releasing its latest EU-wide data on antibiotic resistance, as well as its guidance on prevention and control of carbapenem-resistant Enterobacteriaceae (CRE). In 2016, combined resistance to several antibiotic groups continued to increase for Escherichia coli and Acinetobacter species. This situation is of great concern as patients infected with these multidrug-resistant bacteria have very limited treatment options. (Source: EurekAlert! ...
Source: EurekAlert! - Infectious and Emerging Diseases - November 15, 2017 Category: Infectious Diseases Source Type: news
T2 Biosystems files 510(k) for T2Bacteria Panel
T2 Biosystems Inc. (NSDQ:TTOO) said today it filed a 510(k) appliation with the FDA for its T2Bateria Panel rapid diagnostic solution designed to identify pathogens assocaited with Sepsis.
The T2Bacteria panel is designed to run on the FDA-cleared T2Dx instrument to provide diagnosis of sepsis pathogens within hours, reducing the time for patients with bloodstream infections to receive treatment, the Lexington, Mass.-based company said.
The submission includes data from a pivotal clinical trial of the T2Bacteria Panel which compared it to blood culture, as well as the performance of the panel in known bacteria positive sa...
Source: Mass Device - September 11, 2017 Category: Medical Devices Authors: Fink Densford Tags: Diagnostics Food & Drug Administration (FDA) Regulatory/Compliance T2 Biosystems Inc. Source Type: news
Kitchen sponges may be a 'bacteria hotspot' – but no need to worry
Conclusion
There's no need to panic about the results of this study. Bacteria are everywhere, so it's no surprise to find them growing in kitchens. The researchers say sponges, being porous and usually damp, represent ideal conditions for bacteria to grow.
The study found that one of the most dominant types of bacteria came from the Moraxella family. These bacteria are often found on human skin, so it's likely they got onto the sponges from people's hands. Moraxella are also linked to the unpleasant smell sometimes found after laundry has taken longer to dry, so they seem to be common in the household environment.
The s...
Source: NHS News Feed - August 3, 2017 Category: Consumer Health News Tags: Lifestyle/exercise Source Type: news
Sewage Saved This Man's Life. Someday It Could Save Yours.
This article has been updated to amend overstatements of the length of time it took the Texas A&M team to secure the phages they sent to Patterson, as well as the number of researchers to whom Strathdee reached out. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website. (Source: Science - The Huffington Post)
Source: Science - The Huffington Post - May 11, 2017 Category: Science Source Type: news
Sewage Saved This Man's Life. Someday It Could Save Yours.
When Thomas Patterson woke up from a two-month coma in March 2016, he learned two things he couldn’t believe: Donald Trump was soon to become the Republican nominee for president, and his wife, Steffanie Strathdee, had saved him from dying of an antibiotic-resistant superbug by injecting him with viruses harvested from sewage.
It took a lot of convincing for him to accept these weren’t just more hallucinations.
Patterson and Strathdee met while serving on a National Institutes of Health grant review panel almost 16 years ago. Strathdee doesn’t usually find review panels a riveting experience, but when she...
Source: Healthy Living - The Huffington Post - May 11, 2017 Category: Consumer Health News Source Type: news
Current State and Further Development of Animal Models of Serious Infections Caused by Acinetobacter Baumannii and Pseudomonas Aeruginosa
U.S. Food and Drug Administration. 03/17/2017 This web page provides information, documents, and presentations from a meeting on March 1, 2017, to facilitate the development of narrow-spectrum antibacterial drugs, such as those that are active against only a single species of bacteria that may not occur frequently. Acinetobacter baumannii and Pseudomonas aeruginosa are Priority 1 (Critical) pathogens on the World Health Organization (WHO) priority pathogens list. Animal models of infection may be useful to explore the activity of a candidate antibacterial drug and may help to predict whether the drug will be efficacious in...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - April 6, 2017 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news
These 3 Superbugs Pose The Greatest Risk To Human Health
The World Health Organization is issuing a warning about a group of deadly bacteria: Recently, the WHO released its first-ever list of “priority pathogens,” a list of antibiotic-resistant bacteria that the organization says pose the greatest threat to human health.
The list is divided into three categories: critical-, high- and medium-priority. Three pathogens made it into the critical-priority group. These bacteria are resistant to multiple antibiotics and pose a high risk to people in hospitals and nursing homes, the WHO says.
Multidrug-resistant bacteria, sometimes called “superbugs,” are a ...
Source: Science - The Huffington Post - March 23, 2017 Category: Science Source Type: news
New Antibiotics Urgently Needed to Combat Resistant Bacteria
Credit: WHO/Jim HolmesBy IPS World DeskROME/GENEVA, Feb 28 2017 (IPS)The United Nations health organisation has just published its first ever list of antibiotic-resistant “priority pathogens” – a catalogue of 12 families of bacteria that pose the greatest threat to human health. The list was drawn up in a bid to guide and promote research and development (R&D) of new antibiotics, as part of the World Health Organization (WHO) efforts to address growing global resistance to antimicrobial medicines.The list highlights in particular the threat of gram-negative bacteria that are resistant to multiple antibio...
Source: IPS Inter Press Service - Health - February 28, 2017 Category: Global & Universal Authors: IPS World Desk Tags: Featured Global Headlines Health Human Rights TerraViva United Nations Source Type: news
