Now this is embarrassing . . .
. . . to say the least.  No doubt you have heard  about the misfortune of Jeffrey Toobin but most reports have been somewhat circumspect.The original story broken by Vice is explicit. It seems he was on a Zoom call with fellow New Yorker contributors in which they were somehow simulating election night. (Bizarrely, Masha Gessen was playing Orange Julius.) Anyhooo, as they were going into break rooms Toobin apparently transferred his attention to a video sex service and jerked off (to quote the Vice story directly), thinking he could not be seen by the other participants, but sadly no. I bring this up for the...
Source: Stayin' Alive - October 20, 2020 Category: American Health Source Type: blogs

Dear Newly Diagnosed: What We Wish We Knew
In today’s show, Gabe discusses what he could have done differently as a newly diagnosed bipolar patient that may have made his life a little easier. He and Lisa also discuss some common pitfalls a new patient may run into. For example, what’s the problem when patients are told they need to be med-compliant at all costs? Should you be open at work about your illness? Join us to hear Gabe’s experiences and learn from his rookie mistakes (which actually ended up working out in the end anyway). (Transcript Available Below) Please Subscribe to Our Show: And We Love Written Reviews!  About The Not Crazy podcast ...
Source: World of Psychology - October 20, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Disorders General LifeHelper Mental Health and Wellness Not Crazy Podcast Treatment Source Type: blogs

Fight Aging! Newsletter, October 19th 2020
In conclusion, we found that regardless of the presence of multimorbidity, engaging in a healthier lifestyle was associated with up to 6.3 years longer life for men and 7.6 years for women; however, not all lifestyle risk factors equally correlated with life expectancy, with smoking being significantly worse than others. A Hydrogel Scaffold to Encourage Peripheral Nerve Regeneration https://www.fightaging.org/archives/2020/10/a-hydrogel-scaffold-to-encourage-peripheral-nerve-regeneration/ The nervous system of mammals is poorly regenerative at best. The use of implantable scaffold materials is one of th...
Source: Fight Aging! - October 18, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Using CRISPR to Remove Mutated Sequences of Nuclear DNA Required by Cancerous Cells
Fusion genes feature in many cancers, a form of mutation in which two genes are joined together, such as through deletion of the DNA sequences that normally separate the two genes. The resulting mutant fusion gene sequence encodes a fusion protein that can have novel effects, or in which both portions remain functional, but are now produced in at inappropriate times and in inappropriate amounts. This change in cell biochemistry can be important in driving cancerous behavior, and this appears to be the case in a meaningful fraction of cancer types. Today's research materials discuss a clever use of CRISPR DNA editing...
Source: Fight Aging! - October 16, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Developing a Culture of Safety in Biomedical Research Training
NIGMS is committed to supporting safety in the nation’s biomedical research and training environments. Last April, we shared with you resources for enhancing lab safety in biomedical research training environments. Now, in a perspective in the current issue of Molecular Biology of the Cell (MBoC), we focus on strategies for improving laboratory safety. Some of these strategies are also applicable to other forms of safety including the prevention of harassment, intimidation, and discrimination. We frame the problem of laboratory safety using a number of recent examples of tragic accidents, highlight some of the lessons th...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - October 15, 2020 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages News Resources Training/Fellowships/Career Development Research Resources Science Education Webinars Source Type: blogs

A Hydrogel Scaffold to Encourage Peripheral Nerve Regeneration
The nervous system of mammals is poorly regenerative at best. The use of implantable scaffold materials is one of the strategies under development in the tissue engineering community to encourage greater degrees of regrowth following nerve damage. Such materials can be infused with chemical cues to guide cell activity, or provided with other useful properties such as conductivity. The work noted here is an example of this field of research and development, quite similar to many other studies conducted over the past decade or more. As for all medical research in this heavily regulated environment, it is slow to make it to t...
Source: Fight Aging! - October 14, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Understanding a Dysfunctional Childhood
Let’s discuss the nuances of dysfunctional parenting. In today’s Not Crazy podcast, Gabe recalls the relationship he had with his parents when he was young. As a teen, he thought his parents were being overly harsh, but now he sees they were trying to punish symptoms of his undiagnosed bipolar disorder — and were doing the best they could. Join us for a great discussion on how the parent-child dynamic can go wrong when undiagnosed mental illness is involved. (Transcript Available Below) Please Subscribe to Our Show: And We Love Written Reviews!  About The Not Crazy podcast Hosts Gabe Howard is an award-win...
Source: World of Psychology - October 13, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Bipolar Children and Teens Disorders Family Not Crazy Podcast Parenting Source Type: blogs

Springboard: Beginning to live life again
Springboard is a six week, 120 min once a week programme for people with pain. I developed this programme in the context of New Zealand’s Accident Compensation Corporation (ACC) community-based pain management services. So, why use a group approach and what’s inside Springboard? Pain can be such an isolating experience, and for many people, not only do friends and family not “get it” but neither do some of their health professionals! Living with pain, even for “just” a few months can lead to loneliness because most people don’t know what it is like to experience pain that do...
Source: HealthSkills Weblog - October 11, 2020 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: ACT - Acceptance & Commitment Therapy Coping Skills Coping strategies Groupwork Pain Pain conditions Professional topics Resilience/Health Springboard Source Type: blogs

Fight Aging! Newsletter, October 12th 2020
We report that FMT from aged donors led to impaired spatial learning and memory in young adult recipients, whereas anxiety, explorative behaviour, and locomotor activity remained unaffected. This was paralleled by altered expression of proteins involved in synaptic plasticity and neurotransmission in the hippocampus. Also, a strong reduction of bacteria associated with short-chain fatty acids (SCFAs) production (Lachnospiraceae, Faecalibaculum, and Ruminococcaceae) and disorders of the CNS (Prevotellaceae and Ruminococcaceae) was observed. Finally, the detrimental effect of FMT from aged donors on the CNS was confir...
Source: Fight Aging! - October 11, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An Example of the Beneficial Role of Senescence in Injury
Researchers here provide an interesting demonstration of the beneficial role of transient cellular senescence in injury. Applying senolytics to selectively destroy senescent cells immediately following traumatic injury greatly worsens the consequences. Senescent cells are harmful when they build up and linger in tissues over the course of later life. The signaling they generate is useful in the short-term, such as by mobilizing the response to injury in numerous cell populations, but very damaging when sustained for the long term. This dynamic is one of the reasons why we should favor infrequent senolytic therapies that de...
Source: Fight Aging! - October 8, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Gruesome Descriptions Can Make Crimes Seem Worse — But Judges And Lawyers Are Immune To This Bias
By Matthew Warren We often like to think of ourselves as impartial decision-makers — but of course, nothing could be further from the truth. Our day-to-day thoughts and behaviours are biased in all kinds of ways. But is the same true for people in the legal profession, which prides itself on its supposed objectivity and fairness? According to a new study in Humanities and Social Sciences Communications, judges and lawyers may be immune to at least some of the biases that affect the rest of us. In particular, their judgements seem less prone to the biasing effects of emotive language. Sandra Baez from Universi...
Source: BPS RESEARCH DIGEST - October 7, 2020 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Forensic Language Source Type: blogs

Podcast: Is Happiness a Choice?
Are you sad? Just be happy! Does this irritate you? In today’s show, Gabe and Lisa ponder whether happiness really is a choice — especially for people who struggle with mental illness. How do we measure happiness? And what is happiness inflation? Join us for an in-depth conversation on whether or not people can actually choose happiness. (Transcript Available Below) Please Subscribe to Our Show: And We Love Written Reviews!  About The Not Crazy podcast Hosts Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, Mental Illness is an Asshole a...
Source: World of Psychology - October 6, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: General Happiness Mental Health and Wellness Not Crazy Podcast Source Type: blogs

Trying to Make AI Less Squirrelly
By KIM BELLARD You may have missed it, but the Association for the Advancement of Artificial Intelligence (AAAI) just announced its first annual Squirrel AI award winner: Regina Barzilay, a professor at MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL).   In fact, if you’re like me, you may have missed that there was a Squirrel AI award.  But there is, and it’s kind of a big deal, especially for healthcare – as Professor Barzilay’s work illustrates.  The Squirrel AI Award for Artificial Intelligence for the Benefit of Humanity (Squirrel AI is a Chinese-based AI-powere...
Source: The Health Care Blog - September 29, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech AI Kim Bellard Regina Barzilay Squirrel AI award Source Type: blogs

The Future of Emergency Medicine: 6 Technologies That Make Patients The Point-of-Care
Car crashes, home injuries, fires, natural disasters: every minute – if not every second – spent without treatment in such cases of medical emergencies and high-risk patients could reduce the chance of survival or proper recovery. In fact, when deprived of oxygen, permanent brain damage begins after only 4 minutes, while death can occur as soon as 4-6 minutes later. In this race against time, digital health technologies that turn patients into the point-of-care could prove to be game-changers for first responders and emergency units.  From driverless cars through medical drones to artificial intelligence (...
Source: The Medical Futurist - September 29, 2020 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine Healthcare Design Healthcare Policy Portable Medical Diagnostics Robotics Telemedicine & Smartphones digital health Health 2.0 Innovation technology emergency emergency medicin Source Type: blogs

Penicillin: the accident that saved many lives
Alexander Fleming in his laboratory, 1881 – 1955   There have been many happy accidents in science. Several of these were of great benefit to medicine. For example, in 1895, a German physicist working with a cathode ray tube happened to place his hand in front of the rays and found that he could see his bones in the image projected onto the screen. Soon after that, the first X-ray images were produced. There have been other instances where serendipity played a role in unearthing effective treatments against diseases.    THE FIND OF THE 20TH CENTURY The most famous of these happy accidents is the discovery ...
Source: GIDEON blog - September 28, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Microbiology News Source Type: blogs