Sudden shock with a Nasty looking ECG. What is it?
A 60-something woman complained of sudden severe abd pain. She was found by medics agitated, hypotensive, diaphoretic, and in shock.There were 2 prehospital ECGs:What do you think?Smith: Uncertain supraventricular rhythm with PVCs. (SeeKen Grauer ' s analysis below). There is " shark fin " in I and aVL, which is due to a combination of a large R-wave due to left anterior fascicular block plus downsloping ST elevation due to OMI.  There is reciprocal STD in inferior leads.  There is a rather large R-wave in lead V1 and a very large R-wave in V2, suggesting an atypical RBBB.  There is huge ST depression across...
Source: Dr. Smith's ECG Blog - May 3, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs

Lean Digital: How Tracking Feeds Into Behavior Change for Weight Loss
This article is part of a series on today’s philosophies regarding weight change and how digital interventions can help. In this article, we’ll look at the contribution of tracking. The article looks at standards, making sure data meets a useful need, and some particular applications of tracking to metabolic control and diet. Finding Meaning in Data Device manufacturers are finding more and more things to track. While some people love measurements such as steps taken through the day, and there’s even a site called Quantified Self exploiting this fad, most people don’t care about data unless they s...
Source: EMR and HIPAA - May 2, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Behavior Management Behavioral Change Candice Source Type: blogs

Analyzing Aggression in Female Fruit Flies: Q & A With Caroline Palavicino-Maggio
Credit: Courtesy of Dr. Caroline Palavicino-Maggio. “Turning personal grief into a relentless drive for answers and action has been a big part of my life,” says Caroline Palavicino-Maggio, Ph.D., the director of the Neurobiological Mechanisms of Aggression Laboratory at McLean Hospital in Belmont, Massachusetts. Her sister’s death played a large role in her decision to study the biological mechanisms of behavior and do advocacy work in mental wellness. We spoke with Dr. Palavicino-Maggio about what her path was to becoming a researcher, what she’s learning about the cellular basis of aggression, and why she belie...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 1, 2024 Category: Research Authors: Chrissa Chverchko Tags: Uncategorized Source Type: blogs

Presence With Patients is a Gift: Building Meaningful Patient Relationships
On this episode of the Academic Medicine Podcast, Katherine Chretien, MD, Grant Wilson, MD, and Michelle York, MD, join host Toni Gallo to discuss building meaningful relationships with patients, the small but impactful ways they show their patients they care, and the important role that learners play in connecting with patients and contributing to their care. This episode is now available through Apple Podcasts, Spotify, and anywhere else podcasts are available. A transcript is below. Check out the essay discussed in this episode. Read the essay: Chretien KC. Biopsy. Acad Med. 2023;98:1419. Li...
Source: Academic Medicine Blog - April 30, 2024 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Academic Medicine podcast doctor-patient relationship humanism learners medical students patient centered care Source Type: blogs

A Peek At QuantumSI's Protein Sequencer
A number of academic labs and startups have been trying to build new ways of parallel sequencing of large numbers of peptides using schemes that have significant resemblance in their logic to the highly parallel DNA sequencing schemes often highlighted in this space; QuantumSI is the first (and so far only) such company to actually commercialize in this space.   Resemblances to NGS but not identity - for a few important reasons.The biggest such challenge is the lack of anything resembling Watson-Crick basepairing in proteins. Sequencing chemistries almost invariably rely on basepairing, with the notable exceptions of Maxa...
Source: Omics! Omics! - April 30, 2024 Category: Bioinformatics Authors: Keith Robison Source Type: blogs

Fight Aging! Newsletter, April 29th 2024
In conclusion, we assigned stemness scores to human samples and show evidence of a pan-tissue loss of stemness during human aging, which adds weight to the idea that stem cell deterioration may contribute to human aging. « Back to Top The Role of Immune Aging in Neurodegenerative Conditions https://www.fightaging.org/archives/2024/04/the-role-of-immune-aging-in-neurodegenerative-conditions/ The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of neurodegenerative conditions. Inflammation in the short term is n...
Source: Fight Aging! - April 28, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Atrial dilatation in Atrial fibrillation : A query with multiple twists!
(This is supposed to be a poll. Sorry, readers, you can’t select the answer. WordPress is not kind enough and suddenly made the poll service payable extra. I am already paying nearly a $100 fee to maintain this site. I can’t afford any more.) We have been taught Bi-Atrial enlargement is the rule in AF .It is still true in most situations. But, we rarely dispute it , & ask which atrium dilates more in AF ? Let us see few factors. Both atria develop from a combination of the primitive atrium, sinus venous, and pulmonary veins.It is logical to presume there must be a hidden morpho-electrical ...
Source: Dr.S.Venkatesan MD - April 28, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized atrial cardiomyopathy atrial fibrillation biatrial enlargement in af dispropotinate atrial enlargement in af left atrial cardiomyopathy left atrial fibrillation left atrial vs right atrial fibrillation lone af non pulmonary Source Type: blogs

The Challenges Inherent in Understanding a Fast-Moving, Developing Field
This messy popular science article is an essay length expression of futility on the part of a journalist who accepts that he is not equipped to understand the field of aging research and the longevity industry that has arisen in the past decade. One can talk to the talking heads, but they will all say something different. One can look for proof of efficacy for specific approaches, and find only contradictory data, or only compelling animal data, or only small effect sizes, and a lack of the sort of certainty that arises from large human trials. Those trials are still in the future for near every approach to the treatment o...
Source: Fight Aging! - April 25, 2024 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Navigating COVID: a journey from academic intensity to healing
Springtime. Blooming trees. Green grass. Cool winds. Sunny skies. COVID. That is where my mind wanders every year since 2020, when the season turns. I flash back to the drive between the hospital and my home. Every evening after fighting a losing battle at an academic institution hell-bent on ignoring and downplaying the horror that Read more… Navigating COVID: a journey from academic intensity to healing originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 25, 2024 Category: General Medicine Authors: Tags: Conditions COVID Critical Care Source Type: blogs

Leveraging AI to Address the Mental Health Crisis
The following is a guest article by Raj Tumuluri, Founder and CEO at Openstream.ai As healthcare providers, you are acutely aware of the staggering mental health challenges facing our societies today. Depression, anxiety, PTSD, and suicidal ideation have reached pandemic levels, exacerbated by the relentless pace of modern life. From the general population to students in high-stress environments and frontline workers, a severe shortage of clinical personnel has created harrowing bottlenecks in accessing timely mental health evaluations and care. The weight of this crisis calls for innovative solutions that can simultaneous...
Source: EMR and HIPAA - April 24, 2024 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT AI Avatars Behaviorial Health AI CAI Conversational AI Conversational Artificial Intelligence Healthcare AI mental health Mental Health AI Mental Health Crisis Openstream.ai Raj Source Type: blogs

Managing Your Doctor Self
I’m having a conversation with a colleague when our talk drifted to how are we managing our lives. “How are you managing your physician life?” I asked. I am in the middle of pivoting professional directions, easing out on one an aspect of my physician life. So, maybe I could get an insight into how they balance all these amidst their very busy practice and learn something I could apply in my own life context. “You mean our academic, clinical and administrative life as a doctor? or all of that plus our family??!” She jokingly scoffed. The couple are surgeons, both taking masters degree, bot...
Source: The Orthopedic Logbook - April 20, 2024 Category: Orthopaedics Authors: Remo Aguilar Tags: Habits Productivity doctors managing oneself physicians self management Source Type: blogs

From Patent To Product: The Speed Of The Digital Health Evolution
We’re bombarded with mindblowing headlines of new medical miracles every day. BCI helps paralysed patients talk again! Robots in the stomach! Micro-organs on organ-on-chip technologies! But it is almost impossible to see through the hype and know if and when these will yield actual, patient-ready solutions. So let’s get into this maze and decipher how a new, revolutionary medical technology develops from an ingenious idea to a market-ready product with two real-life examples: the artificial pancreas and wireless ECG. In early April, the UK’s NHS rolled out an artificial pancreas (APS) for Type 1 diabetes patients,...
Source: The Medical Futurist - April 16, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF artificial intelligence digital health Innovation patent analysis Medicine Source Type: blogs

Academic Medicine Call for Volunteer Assistant Editors  
Academic Medicine is seeking applications for volunteer assistant editors. The assistant editor role is characterized by  Working closely with the editor-in-chief, associate editors, and editorial staff on matters related to manuscript review and decision-making  Strengthening experience and skills related to writing, reviewing, and editing content for scholarly publication  Attending annual Academic Medicine editorial board meetings   Successful candidates will have experience reviewing for our journal and demonstrate a strong interest in medical education and scholarly publishing. Priority will be ...
Source: Academic Medicine Blog - April 15, 2024 Category: Universities & Medical Training Authors: hgrimmaamc Tags: Call for Assistant Editors medical education scholarly publishing Source Type: blogs

Fight Aging! Newsletter, April 15th 2024
In conclusion, although several clinical trials targeting SnCs are ongoing, various questions about the biology of SnCs remain open, resulting in a gap between molecular and cellular data. Concerning the need, initiatives such as SenNet aiming to create openly accessible atlases of SnCs should contribute enormously to the area. Advances in understanding the subcellular structure, the heterogeneity, and the dynamics of SnCs require the integration of molecular and cellular techniques with data analysis packages to evaluate high throughput evidence from microscopy and flow cytometry. It is also necessary to develop new equip...
Source: Fight Aging! - April 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Does non -IRA lesion status confuse you : Try a blind primary PCI !
Primary PCI of IRA is a legally, & globally validated  (of course with lots of ifs & buts) coronary reperfusion strategy. What to do, if  we happen to detect, a significant or borderline lesion in non- IRA territory ? There are too many guidelines scattered across cardiology literature either to “help or confuse” us. They argue for either immediate intervention , defer transiently, postpone or just ignore it , based on clinical ,hemodynamic*, Individual, institutional , or some other non academic factors. (Permanently deferred PCI is other wise called medical management is practiced by s...
Source: Dr.S.Venkatesan MD - April 13, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs