Is there association of olanzapine and pulmonary embolism: A case report

This case report described a 36-year-old man who developed pulmonary embolism with 5  years' oral antipsychotic drugs. 3 days before being admitted, he was vaccinated with COVID-19 vaccine. He had risk factor of smoking, obesity, and hyperlipidemia for VTD. AbstractOlanzapine is a second-generation antipsychotic drug that is often used to treat schizophrenia and manic attacks. An increasing number of cases in recent years have shown that olanzapine is associated with vascular thromboembolic disease (VTD). Here, we reported a case of patient with history of taking aripiprazole, benzhexol, olanzapine, and sertraline for 5  years. He was admitted because of aggravated chest tightness, chest pain, and shortness of breath sustaining for 3 days. Laboratory examination and computed tomography angiography of the chest revealed new pulmonary embolus which involved the main trunk of the pulmonary artery and bilateral pulmo nary arteries, with pneumonic infiltration in the left upper lobe. After thrombolytic therapy, the patient was out of danger.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research