S-ketamine promotes autophagy and alleviates neuropathic pain by inhibiting PI3K/Akt/mTOR signaling pathway

ConclusionS-ketamine could induce autophagy to alleviate neuropathic pain by inhibition of the PI3K/Akt/mTOR pathway. These findings facilitate understating on the molecular mechanism underlying the protective effects of S-ketamine on neuropathic pain.
Source: Molecular and Cellular Toxicology - Category: Cytology Source Type: research