Dexmedetomidine reduces propofol-induced hippocampal neuron injury by modulating the miR-377-5p/Arc pathway

Propofol and dexmedetomidine (DEX) are widely used in general anesthesia, and exert toxic and protective effects on hippocampal neurons, respectively. The study sought to investigate the molecular mechanisms o...

Source: BMC Clinical Pharmacology - March 25, 2022 Category: Drugs & Pharmacology Authors: Zong Chen, Yong Ding, Ying Zeng, Xue-Ping Zhang and Jian-Yan Chen Tags: Research Source Type: research