Long-term Effect of Permanent Demyelination on Axonal Survival in Multiple Sclerosis

Discussion
Our study provides clear in vivo evidence that chronic demyelination significantly accelerates axonal loss. However, because this process is slow and its effect is mild, long-term monitoring is required to establish and confidently measure the neurodegenerative consequences of demyelination.

Source: Neurology Neuroimmunology and Neuroinflammation - March 3, 2022 Category: Neurology Authors: Klistorner, A., Klistorner, S., You, Y., Graham, S. L., Yiannikas, C., Parratt, J., Barnett, M. Tags: Optic nerve, Evoked Potentials/Visual, Multiple sclerosis, Optic neuritis; see Neuro-ophthalmology/Optic Nerve Article Source Type: research