The protective effect of hypericin on postpartum depression rat model by inhibiting the NLRP3 inflammasome activation and regulating glucocorticoid metabolism

CONCLUSION: All those data suggest that HY can effectively relieve PPD by reversing glucocorticoid metabolism, increasing ER expression, and then relieve neuroinflammation.PMID:35101848 | DOI:10.1016/j.intimp.2022.108560

Source: International Immunopharmacology - February 1, 2022 Category: Allergy & Immunology Authors: Xuejia Zhai Yan Chen Xuemei Han Ying Zhu Xixuan Li Yu Zhang Yongning Lu Source Type: research