Neuromics ' Human Brian Microvascular Endothelial Cells in Action

Fc-saxatilin inhibits VEGF-induced permeability by regulating claudin-5 expression in human brain microvascular endothelial cells (HBMVECs)Neuromics ' cells were at the heart of this study.Highlights: Fc-saxatilin prevents VEGF-induced permeability in human brain microvascular cells (HBMVECs). Fc-saxatilin inhibits VEGF-induced Src and Fak phosphorylation in HBMVECs. Fc-saxatilin blocks the downregulation of claudin-5 expression by VEGF in HBMVECs.Image: HMBECS in CultureProtocol: Human brain microvascular endothelial cells (HBMVECs) were purchased from Neuromics (HEC02; Minneapolis, MN, USA). HBMVECs were maintained in ENDO-growth medium (MED001; Neuromics). Here ' s a link to the full study: https://www.sciencedirect.com/science/article/pii/S0026286219301177#!
Source: Neuromics - Category: Neuroscience Tags: human brain microvascular cells Human microvascular endothelial cells Source Type: news