Heart Rate Variability during Wake and Sleep in Huntington ’s Disease Patients: An Observational, Cross-Sectional, Cohort Study

Conclusion: Our results show that HD patients have higher heart rate than controls, during wake and NREM, but not during REM sleep. Among HRV parameters, the most relevant difference regarded the LF component, which reflects, at least partially, the ortho-sympathetic output. Our results confirm the involvement of autonomic nervous system in HD and demonstrate that it is evident during both wake and sleep.
Source: Neurodegenerative Diseases - Category: Neurology Source Type: research