CSF-Derived CD4+ T-Cell Diversity Is Reduced in Patients With Alzheimer Clinical Syndrome

Discussion
Examination of CSF indicates that CD4+ T cell–mediated adaptive immune responses are altered in patients with ACS. Understanding the underlying mechanisms affecting adaptive immunity will help move us toward the goal of slowing cognitive decline.

Source: Neurology Neuroimmunology and Neuroinflammation - November 30, 2021 Category: Neurology Authors: Joshi, C., Sivaprakasam, K., Christley, S., Ireland, S., Rivas, J., Zhang, W., Sader, D., Logan, R., Lambracht-Washington, D., Rosenberg, R., Cullum, M., Hitt, B., Li, Q.-Z., Barber, R., Greenberg, B., Cowell, L., Zhang, R., Stowe, A., Huebinger, R., Kell Tags: All Immunology, Alzheimer's disease, Gene expression studies Article Source Type: research